CAS 37517-28-5
:Amikacina
Descripción:
Amikacina es un antibiótico aminoglucósido que se utiliza principalmente para tratar infecciones graves causadas por bacterias Gram-negativas, particularmente en casos donde otros antibióticos son ineficaces. Se deriva de la kanamicina y exhibe un amplio espectro de actividad contra varios patógenos, incluyendo Pseudomonas aeruginosa y ciertas cepas de Mycobacterium tuberculosis. Amikacina actúa inhibiendo la síntesis de proteínas bacterianas, lo que conduce a la muerte celular. Se administra típicamente por inyección, ya que se absorbe mal del tracto gastrointestinal. La sustancia se caracteriza por su toxicidad relativamente baja en comparación con otros aminoglucósidos, aunque aún puede causar nefrotoxicidad y ototoxicidad, lo que requiere un monitoreo cuidadoso de la función renal y los niveles de fármacos durante el tratamiento. Amikacina a menudo se reserva para infecciones severas o cuando hay resistencia a otros antibióticos. Su estructura química incluye un grupo amino, que contribuye a su mecanismo de acción y propiedades farmacológicas. Al igual que con todos los antibióticos, el uso apropiado es crucial para prevenir el desarrollo de resistencia.
Fórmula:C22H43N5O13
InChI:InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1
Clave InChI:InChIKey=LKCWBDHBTVXHDL-RMDFUYIESA-N
SMILES:O([C@H]1[C@H](NC([C@H](CCN)O)=O)C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]1O)[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O
Sinónimos:- (2R)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-2-{[(2xi)-3-amino-3-deoxy-alpha-D-arabino-hexopyranosyl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide disulfate (salt)
- (2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-4-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide
- (2S)-4-amino-N-{5-amino-2-[(3-amino-3-deoxyhexopyranosyl)oxy]-4-[(6-amino-6-deoxyhexopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide
- 1-N-(L(-)-gamma-Amino-alpha-hydroxybutyryl)kanamycin A
- 1-N-[<span class="text-smallcaps">L</span>-(-)-γ-Amino-α-hydroxybutyryl]kanamycin A
- 1-N-[L-(-)-γ-Amino-α-hydroxybutyryl]kanamycin A
- 4-amino-N-{5-amino-2-[(3-amino-3-deoxyhexopyranosyl)oxy]-4-[(6-amino-6-deoxyhexopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-N<sup>1</sup>-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)-
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-N<sup>1</sup>-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-
- Amicacin
- Amigasol
- Amiglyde-V
- Amikacillin
- Amikacin Inhalation Solution
- Amikacin [USAN:INN:BAN]
- Amikacina
- Amikacina [INN-Spanish]
- Amikacine
- Amikacine [INN-French]
- Amikacinum
- Amikacinum [INN-Latin]
- Amikavet
- Amikozit
- Amukin
- Antibiotic BB-K 8
- Arikace
- Arikayce
- Bay 41-6551
- Bay 416651
- Bay41-6551
- Bb-K 8
- D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4))-N(sup 1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)-
- D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4))-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)-
- D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1.fwdarw.6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1.fwdarw.4))-N1-((2S)-4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-
- D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)-
- D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-
- Hsdb 3583
- Kaminax
- Lukadin
- Mikavir
- Nsc 177001
- O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-6))-N(sup 3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine
- O-3-Amino-3-deoxy-α-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)]-N<sup>1</sup>-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-<smallcap>D</span>-streptamine
- Pierami
- Potentox
- Unii-84319Sgc3C
- Amikacin
- Amikacin
- Ver más sinónimos
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Encontrado 13 productos.
Amikacin
CAS:Amikacin (Amikacina) is a broad-spectrum antibiotic derived from kanamycin.Fórmula:C22H43N5O13Pureza:97.35% - 99.34%Forma y color:White Crystalline Powder From Methanol-Isopropanol SolidPeso molecular:585.6Amikacin
CAS:<p>Applications Amikacin is an antibacterial compound used in the treatment of diseases and illnesses arising from gram-negative bacterium. Antituberculosis agent.<br>References Villegas, M. et al.: Antimicrob. Agents Chemother., 51, 1553 (2007); Boshoff, H. et al.: J. Biol. CHem., 279, 40174 (2004);<br></p>Fórmula:C22H43N5O13Forma y color:NeatPeso molecular:585.60Amikacin anhydrous
CAS:<p>Inhibitor of protein synthesis; aminoglycoside</p>Fórmula:C22H43N5O13Pureza:Min. 95 Area-%Forma y color:White PowderPeso molecular:585.6 g/molAmikacin (AMK) free base, 98%
CAS:Fórmula:C22H43N5O13Pureza:min. 98%Forma y color:White to off-white, PowderPeso molecular:585.6
