CAS 37682-72-7

L-Valinamida, N2-[[[(1S)-1-carboxi-2-feniletil]amino]carbonil]-L-arginil-N-[4-[(aminoiminometil)amino]-1-formilbutil]-, clorhidrato (1:2)

Descripción:

L-Valinamida, N2-[[[(1S)-1-carboxi-2-feniletil]amino]carbonil]-L-arginil-N-[4-[(aminoiminometil)amino]-1-formilbutil]-, clorhidrato (1:2) es un compuesto orgánico complejo caracterizado por su estructura multifuncional, que incluye derivados de aminoácidos y una forma de sal hidroclorídica. Esta sustancia presenta una combinación de un esqueleto de L-valinamida y un moiety de L-arginina, lo que indica su posible papel en sistemas biológicos, particularmente en la síntesis de péptidos o como un intermedio farmacéutico. La presencia de múltiples grupos funcionales, como ácidos carboxílicos, aminas e iminas, sugiere que puede exhibir diversas propiedades de reactividad y solubilidad. La forma hidroclorídica mejora su estabilidad y solubilidad en entornos acuosos, haciéndola adecuada para diversas aplicaciones en química medicinal. Además, la estereoquímica del compuesto, particularmente la configuración (1S), es crucial para su actividad biológica, influyendo en las interacciones con los objetivos biológicos. En general, la intrincada estructura y diversidad funcional de este compuesto lo posicionan como una entidad significativa en el estudio de moléculas bioactivas y agentes terapéuticos.

Fórmula: C₂₇H₄₄N₁₀O₆·2ClH

InChI: InChI=1S/C27H44N10O6.2ClH/c1-16(2)21(23(40)34-18(15-38)10-6-12-32-25(28)29)37-22(39)19(11-7-13-33-26(30)31)35-27(43)36-20(24(41)42)14-17-8-4-3-5-9-17;;/h3-5,8-9,15-16,18-21H,6-7,10-14H2,1-2H3,(H,34,40)(H,37,39)(H,41,42)(H4,28,29,32)(H4,30,31,33)(H2,35,36,43);2*1H

Clave InChI: InChIKey=YAHXZYICKJUJEO-UHFFFAOYSA-N

SMILES: C(C(NC(C(NC(CCCNC(=N)N)C=O)=O)C(C)C)=O)(NC(NC(CC1=CC=CC=C1)C(O)=O)=O)CCCNC(=N)N.Cl

Sinónimos:

• <span class="text-smallcaps">L</smallcap>-Valinamide, N²-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-<smallcap>L</span>-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, dihydrochloride
• <span class="text-smallcaps">L</smallcap>-Valinamide, N²-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-<smallcap>L</span>-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, hydrochloride (1:2)
• Antipain dihydrochloride
• L-Valinamide, N(sup 2)-(((1-carboxy-2-phenylethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, dihydrochloride
• N-({(1S)-4-[(diaminomethylidene)amino]-1-[(N-{4-[(diaminomethylidene)amino]-1-formylbutyl}-L-valyl)carbamoyl]butyl}carbamoyl)phenylalanine dihydrochloride
• L-Valinamide, N2-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, dihydrochloride
• L-Valinamide, N2-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, hydrochloride (1:2)

Antipain dihydrochloride

CAS: 37682-72-7

Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases. This Thermo Scientific brand product was originally part of the Alfa

Fórmula: C₂₇H₄₄N₁₀O₆•2HCl

Forma y color: White, Powder

Peso molecular: 677.6

Ref: 02-J63680

Antipain dihydrochloride

CAS: 37682-72-7

Antipain dihydrochloride

Forma y color: White To Pale Yellow Powder

Peso molecular: 677.62g/mol

Ref: 54-BIA0201

Antipain dihydrochloride

CAS: 37682-72-7

Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes with analgesic activity.

Fórmula: C₂₇H₄₆Cl₂N₁₀O₆

Pureza: 95%

Forma y color: White To Off-White Powder

Peso molecular: 677.62

Ref: TM-T26637

Antipain dihydrochloride

CAS: 37682-72-7

Fórmula: C₂₇H₄₄N₁₀O₆₂HCl

Peso molecular: 677.60

Ref: 7W-GL6582

Antipain dihydrochloride

CAS: 37682-72-7

Antipain 2HCI is a cytosolic and bound form of antipain. It binds to ATP-binding cassette transporter proteins, which are involved in the transport of substances across cell membranes, and inhibits their enzymatic activity. Antipain 2HCI also has inhibitory properties on enzymes such as DNA polymerase II and pyruvate kinase. It has been shown to have an effect on biochemical properties such as protein synthesis, enzyme activities, and polymerase chain reactions. This drug has been shown to be effective in preventing myocardial infarcts and cellular apoptosis by inhibiting the release of cytochrome c from mitochondria. Antipain 2HCI may also have some anti-inflammatory effects due to its inhibition of prostaglandin synthesis.

Fórmula: C₂₇H₄₄N₁₀O₆•(HCl)₂

Pureza: Min. 95%

Peso molecular: 677.62 g/mol

Ref: 3D-FA29612

Antipain (Synthetic)

CAS: 37682-72-7

Antipain (supplied as the HCl salt) is a cytosolic and bound form of antipain. It binds to ATP-binding cassette transporter proteins, which are involved in the transport of substances across cell membranes, and inhibits their enzymatic activity. Antipain 2HCI also has inhibitory properties on enzymes such as DNA polymerase II and pyruvate kinase. It has been shown to have an effect on biochemical properties such as protein synthesis, enzyme activities, and polymerase chain reactions. This drug has been shown to be effective in preventing myocardial infarcts and cellular apoptosis by inhibiting the release of cytochrome c from mitochondria. Antipain 2HCI may also have some anti-inflammatory effects due to its inhibition of prostaglandin synthesis.

Fórmula: C₂₇H₄₄N₁₀O₆·2HCl

Pureza: Min. 95%

Peso molecular: 604.7 g/mol

Ref: 3D-IAP-3996-PI