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CAS 37933-66-7

:

Tevetina A

Descripción:
Tevetina A es un compuesto tóxico derivado principalmente de las semillas de la planta Thevetia peruviana, comúnmente conocida como el adelfa amarilla. Pertenece a la clase de los glucósidos cardíacos, que son conocidos por su capacidad para afectar la función cardíaca. Tevetina A exhibe una estructura caracterizada por un núcleo esteroide con un moiety de azúcar, lo que contribuye a su actividad biológica. Este compuesto es reconocido por sus potentes efectos cardiotóxicos, que pueden llevar a síntomas como arritmias y trastornos gastrointestinales tras la ingestión. Su mecanismo de acción implica la inhibición de la enzima Na+/K+ ATPasa, lo que lleva a un aumento de los niveles de sodio y calcio intracelular, afectando en última instancia la contractilidad cardíaca. Debido a su toxicidad, Tevetina A no se utiliza terapéuticamente y presenta riesgos significativos si se consume. Las precauciones de seguridad son esenciales al manejar esta sustancia, ya que puede ser letal en pequeñas dosis. La investigación continúa explorando sus posibles aplicaciones en farmacología, pero su naturaleza peligrosa limita su uso práctico.
Fórmula:C42H64O19
InChI:InChI=1S/C42H64O19/c1-18-35(61-38-33(51)31(49)29(47)26(60-38)16-56-37-32(50)30(48)28(46)25(14-43)59-37)36(54-3)34(52)39(57-18)58-21-6-10-41(17-44)20(13-21)4-5-24-23(41)7-9-40(2)22(8-11-42(24,40)53)19-12-27(45)55-15-19/h12,17-18,20-26,28-39,43,46-53H,4-11,13-16H2,1-3H3/t18-,20+,21-,22+,23-,24+,25+,26+,28+,29+,30-,31-,32+,33+,34-,35-,36-,37+,38-,39-,40+,41+,42-/m0/s1
Clave InChI:InChIKey=WPNLWBRKPZXVGD-QMFRUYISSA-N
SMILES:C(=O)[C@@]12[C@@]3([C@]([C@]4(O)[C@](C)(CC3)[C@H](CC4)C=5COC(=O)C5)(CC[C@@]1(C[C@@H](O[C@H]6[C@@H](O)[C@H](OC)[C@@H](O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)[C@H](C)O6)CC2)[H])[H])[H]
Sinónimos:
  • (3beta,5beta)-3-((O-beta-D-glucopyranosyl-(1.6)-O-D-glucopyranosyl-(1.4)-6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy)-14-hydroxy-19-oxocard-20(22)-enolide
  • (3beta,5beta)-3-{[beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl-(1->4)-6-deoxy-3-O-methyl-alpha-L-glucopyranosyl]oxy}-14-hydroxy-19-oxocard-20(22)-enolide
  • (3β,5β)-3-[(O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-<smallcap>L</span>-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
  • 3-{[hexopyranosyl-(1->6)hexopyranosyl-(1->4)-6-deoxy-3-O-methylhexopyranosyl]oxy}-14-hydroxy-19-oxocard-20(22)-enolide
  • 5-beta-Card-20(22)-enolide, 3-beta-((O-beta-D-glucopyranosyl-(1-6)-O-D-glucopyranosyl-(1-4)-6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy)-14-hydroxy-19-oxo-
  • Cannogenin + L-thevetose + 2-glucose
  • Cannogenin + L-thevetose + 2-glucose [German]
  • Card-20(22)-enolide, 3-[(O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-<smallcap>L</span>-glucopyranosyl)oxy]-14-hydroxy-19-oxo-, (3β,5β)-
  • Thevetin A
  • Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxo-, (3β,5β)-
  • (3β,5β)-3-[(O-β-D-Glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
Ordenar por
Pureza (%)
0
100
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0
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50
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90
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95
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100
Encontrado 4 productos.
  • Thevetin A
    Glentham
    + Info

    Thevetin A

    CAS:
    Fórmula:C42H64O19
    Peso molecular:872.95

    Ref: 7W-GL2522

    ne
    A consultar
  • Thevetin A
    Biopurify
    + Info

    Thevetin A

    CAS:
    Fórmula:C42H64O19
    Pureza:95%~99%
    Peso molecular:872.955

    Ref: BP-BP4809

    5mg
    730,00€
  • Thevetin A
    Targetmol
    + Info

    Thevetin A

    CAS:
    <p>Thevetin A is a useful organic compound for research related to life sciences. The catalog number is T124930 and the CAS number is 37933-66-7.</p>
    Fórmula:C42H64O19
    Forma y color:Solid
    Peso molecular:872.955

    Ref: TM-T124930

  • Thevetin A
    Biosynth
    + Info

    Thevetin A

    CAS:
    Thevetin A is an extract from the cascabela tree that contains hydroxy groups. This extract has been shown to have a potent effect in clinical studies as a control agent for congestive heart failure. Thevetin A has also been shown to be effective in treating trigeminal neuralgia and cardiac effects. It is believed that it may be due to its ability to increase the release of norepinephrine and serotonin, which are neurotransmitters that affect pain perception and mood.
    Fórmula:C42H64O19
    Pureza:Min. 95%
    Peso molecular:872.9 g/mol

    Ref: 3D-MBA93366

    1mg
    863,00€
    2mg
    1.036,00€
    5mg
    2.112,00€