CAS 38243-03-7

R-Ginsenoside Rg3

Descripción:

R-Ginsenoside Rg3 es un compuesto natural derivado del ginseng, específicamente un tipo de ginsenosido, que son saponinas esteroides conocidas por sus diversas propiedades farmacológicas. Se caracteriza por su fórmula molecular, que refleja su estructura compleja, presentando típicamente un esqueleto esteroide con moieties de azúcar. Rg3 existe en dos formas estereoisoméricas, siendo la forma R biológicamente activa. Este compuesto es reconocido por sus potenciales beneficios para la salud, incluyendo efectos anticancerígenos, antiinflamatorios y neuroprotectores. Rg3 ha sido estudiado por su capacidad para modular diversas vías biológicas, incluyendo la apoptosis y la proliferación celular, lo que lo hace de interés tanto en la medicina tradicional como en la farmacología moderna. Además, a menudo se explora en el contexto de mejorar la función inmunológica y la vitalidad general. Su solubilidad y estabilidad pueden variar según la formulación y las condiciones, que son consideraciones importantes para su aplicación en suplementos dietéticos y agentes terapéuticos. En general, R-Ginsenoside Rg3 representa un área significativa de investigación en la química de productos naturales y aplicaciones medicinales.

Fórmula: C₄₂H₇₂O₁₃

InChI: InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,51)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-37-35(33(49)31(47)25(20-44)53-37)55-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42+/m0/s1

Clave InChI: InChIKey=RWXIFXNRCLMQCD-CZIWJLDFSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]5[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@@H](CO)O5)CC4)[H])[H])[H]

Sinónimos:

• (20S)-Propanaxadiol
• (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxa
• (3Beta,12Beta)-12,20-Dihydroxydammar-24-En-3-Yl 2-O-Beta-D-Glucopyranosyl-Beta-D-Glucopyranoside
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranoside
• (5xi,8xi,9xi,12alpha,14beta,20R)-12,20-dihydroxylanost-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• (8xi,9xi,12alpha,14beta,17alpha)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,14-tetramethylgonan-3-yl 2-O-[3-deoxy-3-(hydroxymethyl)-beta-D-glucopyranosyl]-beta-D-glucopyranoside
• 20(R)-Ginsenoside Rg₃
• 20(R)-Propanaxadiol
• 20(S)-Ginsenoside-Rg3
• 20R-Ginsenoside Rg3
• Beta-D-Glucopyranoside,(3-Beta,12-Beta)-12,20-Dihydroxydammar-24-En-3-Yl2-O-B
• Dammar-24-Ene-12-Beta,20-Diol,3-Beta-((2-O-Beta-D-Glucopyranosyl-Beta-D-Gluc
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-D-
• Eta-D-Glucopyranosyl-
• Ginsenoside rg3(R)
• Opyransoyl)Oxy)-
• R-Ginsenoside Rg₃
• beta-D-Glucopyranoside,(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β,20R)-12,20-dihydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
• 20(R)-Ginsenoside Rg3
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside

20(R)-Propanaxadiol

CAS: 38243-03-7

Ref: 7W-GC5327

(20R)-Ginsenoside Rg3

CAS: 38243-03-7

(20R)-Ginsenoside Rg3

Pureza: ≥95%

Peso molecular: 785.01g/mol

Ref: 54-BUP00028

20(R)-Ginsenoside Rg3

CAS: 38243-03-7

20(R)-Ginsenoside Rg3 has shown multiple pharmacological activities and been considered as one of the most promising approaches for fatigue treatment, however, 20(R)-Ginsenoside Rg3 has a low bioavailability after oral administration in human, so, 20(R)-Rg3 can be by intranasal administration, the mechanism was related to the increase of the storage of hepatic glycogen, and the decrease of the accumulation of metabolite such as lactic acid and serum urea nitrogen.

Fórmula: C₄₂H₇₂O₁₃

Pureza: 95%~99%

Forma y color: White powder

Peso molecular: 785.025

Ref: BP-BP0040

20(R)-Ginsenoside Rg3

CAS: 38243-03-7

Fórmula: C₄₂H₇₂O₁₃

Pureza: >97.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 785.03

Ref: 3B-G0536

(20R)-Ginsenoside Rg3

CAS: 38243-03-7

(20R)-Ginsenoside Rg3 (20(R)-Propanaxadiol) is a compound with anti-aging and antifatigue activities.

Fórmula: C₄₂H₇₂O₁₃

Pureza: 97.03% - 99.67%

Forma y color: Solid

Peso molecular: 785.01

Ref: TM-T3812

20(R)-Ginsenoside Rg3

Producto controlado

CAS: 38243-03-7

Applications 20(R)-Ginsenoside Rg3 causes an inhibition of phosphatidylinositol 3-kinase/Akt activation that, in turn, results in modulations in Bcl-2 family proteins in such a way that the apoptosis of U87 cells are regulated. Elicits a significant inhibition of in vitro cell adhesion and invasion of U87 cells. in vitro stereoselective inhibition of ginsenosides toward UDP-glucuronosyltransferase isoforms and in vivo inhibition of tumor angiogenesis of lung cancer.
References Liu, Y., et al.: Chengdu Yixueyuan Xuebao, 9, 4 (2014); Liu, Y., et al.: Linchuang Junyi Zazhi, 42, 1138 (2014), Kim, D., et al.: Toxicol. Lett., 259, 1 92016); Geng, L., et al.: Zhonghua Zhongyiyao Zazhi, 29, 601 (2014)

Fórmula: C₄₂H₇₂O₁₃

Forma y color: Neat

Peso molecular: 785.01

Ref: TR-G387625

(20R)-Ginsenoside Rg3

CAS: 38243-03-7

(20R)-Ginsenoside Rg3 is a triterpenoid saponin, which is a bioactive compound isolated from the root of Panax ginseng. This product is an integral part of traditional medicine and is now being extensively studied in modern pharmacological research. As a ginsenoside, Rg3 exerts its effects primarily by modulating cellular pathways, inhibiting angiogenesis, and inducing apoptosis in cancer cells.

Fórmula: C₄₂H₇₂O₁₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 785.01 g/mol

Ref: 3D-OG15964

20(R)-Ginsenoside Rg3-d6

Producto controlado

CAS: 38243-03-7

Fórmula: C₄₂D₆H₆₆O₁₃

Forma y color: Neat

Peso molecular: 791.05

Ref: TR-G410288

20(R)-Propanaxadiol

CAS: 38243-03-7

Fórmula: C₄₂H₇₂O₁₃

Forma y color: Solid

Peso molecular: 785.0133

Ref: IN-DA00BXSG