CAS 3847-29-8

Lactobionato de eritromicina

Descripción:

Lactobionato de eritromicina es un antibiótico macrólido derivado de la bacteria Saccharopolyspora erythraea. Se utiliza principalmente para tratar diversas infecciones bacterianas, particularmente aquellas causadas por bacterias Gram-positivas y algunos organismos Gram-negativos. La sustancia se caracteriza por su forma de sal lactobionato, que mejora su solubilidad en agua, haciéndola adecuada para la administración intravenosa. Lactobionato de eritromicina exhibe un amplio espectro de actividad contra infecciones del tracto respiratorio, infecciones cutáneas y ciertas enfermedades de transmisión sexual. Su mecanismo de acción implica la inhibición de la síntesis de proteínas bacterianas al unirse a la subunidad ribosomal 50S, impidiendo así el crecimiento y la reproducción de las bacterias. El compuesto generalmente es bien tolerado, aunque puede causar efectos secundarios gastrointestinales y tiene interacciones potenciales con otros medicamentos debido a su efecto sobre las enzimas hepáticas. Al igual que con todos los antibióticos, el uso apropiado es crucial para prevenir el desarrollo de resistencia a los antibióticos.

Fórmula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

InChI: InChI=1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3-10,12-20H,1-2H2,(H,21,22)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1

Clave InChI: InChIKey=NNRXCKZMQLFUPL-WBMZRJHASA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3.[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)([C@@H]([C@H](C(O)=O)O)O)[C@@H](CO)O

Sinónimos:

• (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexanoic acid - (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (1:1) (non-preferred name)
• 4-O-beta-D-Galactopyranosyl-D-gluconic acid compd. with erythromycin
• <span class="text-smallcaps">D</smallcap>-Gluconic acid, 4-O-β-<smallcap>D</span>-galactopyranosyl-, compd. with erythromycin (1:1)
• D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, compd. with erythromycin (1:1) (9CI)
• Erythrocin Lactobionate IV
• Erythrocin lactobionate
• Erythromycin lactobionate (1:1) (salt)
• Erythromycin mono(4-O-beta-D-galactopyranosyl-D-gluconate) (salt)
• Erythromycin, 4-O-beta-D-galactopyranosyl-D-gluconate (salt)
• Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (1:1)
• Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (salt)
• Erythromycin. compd. with lactobionic acid
• Lactobionic acid, compd. with erythromycin (1:1)
• Oxacyclotetradecane, erythromycin deriv.
• Erythromycin, 4-O-β-D-galactopyranosyl-D-gluconate (1:1)

ERYTHROMYCIN LACTOBIONATE CRS

CAS: 3847-29-8

ERYTHROMYCIN LACTOBIONATE CRS

Fórmula: C₄₉H₈₉NO₂₅

Peso molecular: 1092.223

Ref: 41-Y0001848

Erythromycin Lactobionate

CAS: 3847-29-8

Erythromycin and its derivatives; salts thereof

Fórmula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

Forma y color: White Off-White Powder

Peso molecular: 1091.57237

Ref: 45-1247003

Erythromycin Lactobionate

CAS: 3847-29-8

Fórmula: C₄₉H₈₉NO₂₅

Pureza: 98%

Forma y color: Solid

Peso molecular: 1092.2227

Ref: IN-DA0079PQ

Erythromycin lactobionate

CAS: 3847-29-8

Erythromycin, a macrolide antibiotic, inhibits bacterial protein synthesis, effective against Streptococcus and Staphylococcus, and affects CYP3A4 metabolism.

Fórmula: C₄₉H₈₉NO₂₅

Forma y color: Solid

Peso molecular: 1092.233

Ref: TM-T37433

Erythromycin Lactobionate

Producto controlado

CAS: 3847-29-8

Applications Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs.
References Kiso, S. et al.: Anticanc. Res., 20, 2827 (2000); Broad, J. et al.: Brit. J. Pharm., 168,1859 (2013); Itoh, Z., et al.: Antimicrob. Agents Chemother., 26, 863(1984)

Fórmula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

Forma y color: Neat

Peso molecular: 1092.22

Ref: TR-E650040

Erythromycin iactobionate

CAS: 3847-29-8

Erythromycin lactobionate is a macrolide antibiotic, which is derived from the bacterium *Saccharopolyspora erythraea*. Its mode of action involves binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis and leading to the suppression of bacterial growth. This mechanism effectively targets gram-positive bacteria and some gram-negative bacteria, making it a crucial agent in the fight against various bacterial infections.

Fórmula: C₄₉H₈₇NO₂₄

Pureza: Min. 95%

Forma y color: White To Off-White Solid

Peso molecular: 1,074.21 g/mol

Ref: 3D-AE37145

Erythromycin lactobioate A

CAS: 3847-29-8

Fórmula: C₃₇H₆₇NO₁₃C₁₂H₂₂O₁₂

Peso molecular: 733.94 : 358.3

Ref: ST-EA-CP-E18027