CAS 387-79-1

17-Hidroxipregnenolona

Descripción:

17-Hidroxipregnenolona es una hormona esteroide que sirve como precursor en la biosíntesis de otras hormonas esteroides, incluyendo progesterona y cortisol. Se deriva de la pregnenolona a través de la acción de la enzima 17α-hidroxilasa. Este compuesto se caracteriza por su estructura esteroide, que incluye un marco de carbono de cuatro anillos típico de los esteroides, con un grupo hidroxilo (-OH) en la posición 17 del carbono. Es un sólido cristalino incoloro a amarillo pálido que es soluble en disolventes orgánicos pero tiene una solubilidad limitada en agua. 17-Hidroxipregnenolona juega un papel significativo en la corteza adrenal y está involucrado en la regulación de varios procesos fisiológicos, incluyendo la respuesta al estrés y el metabolismo. Sus niveles pueden verse influenciados por factores como la edad, el sexo y el estado de salud. En entornos clínicos, puede medirse para evaluar la función adrenal o diagnosticar ciertos trastornos relacionados con la esteroidogénesis. Al igual que con muchas hormonas esteroides, es importante manejar 17-Hidroxipregnenolona con cuidado debido a su actividad biológica y sus posibles efectos en el equilibrio hormonal.

Fórmula: C₂₁H₃₂O₃

InChI: InChI=1S/C21H32O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4,15-18,23-24H,5-12H2,1-3H3/t15-,16+,17-,18-,19-,20-,21-/m0/s1

Clave InChI: InChIKey=JERGUCIJOXJXHF-TVWVXWENSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]

Sinónimos:

• (3Beta,14Xi)-3,17-Dihydroxypregn-5-En-20-One
• (3beta)-3,17-Dihydroxypregn-5-en-20-one
• (3β)-3,17-Dihydroxypregn-5-en-20-one
• 17-Hydroxy-Δ5-pregnenolone
• 17-Hydroxy-Δ⁵-pregnenolone
• 17-Hydroxypregnenolone
• 17alpha-Hydroxypregnenolone
• 3,17-Dihydroxypregn-5-En-20-One
• 3-Beta,17-Alpha-Dihydroxypregn-5-En-20-One
• 3-Β,17-Α-Dihidroxipregn-5-En-20-Ona
• 3-Β,17-Α-Dihydroxypregn-5-En-20-One
• 3-Β,17-Α-Dihydroxypregn-5-Ene-20-One
• 3-β,17-α-Dihydroxypregn-5-en-20-on
• 3b,17-Dihydroxy-5-pregnen-20-one
• 3b,17-dihydroxy-Pregn-5-en-20-one
• 3b,17a-Dihydroxypregn-5-en-20-one
• 3beta,17alpha-Dihydroxy-5-pregnen-20-one
• 5-Pregnen-3β,17α-diol-20-one
• Hydroxypregnenolone
• Nsc 63853
• Pregn-5-En-20-One, 3,17-Dihydroxy-, (3Beta)-
• Pregn-5-en-20-one, 3,17-dihydroxy-, (3.beta.)-
• Pregn-5-en-20-one, 3,17-dihydroxy-, (3β)-
• Pregn-5-en-20-one, 3.beta.,17-dihydroxy-
• Pregn-5-en-20-one, 3β,17-dihydroxy-
• 17α-Hydroxypregnenolone

Pregn-5-en-20-one, 3,17-dihydroxy-, (3b)-

CAS: 387-79-1

Fórmula: C₂₁H₃₂O₃

Pureza: 95%

Forma y color: Solid

Peso molecular: 332.4770

Ref: IN-DA00I7OD

17a-Hydroxypregnenolone

CAS: 387-79-1

17a-Hydroxypregnenolone

Pureza: ≥98%

Peso molecular: 332.48g/mol

Ref: 54-BUP11678

17-Hydroxy Pregnenolone

CAS: 387-79-1

Fórmula: C₂₁H₃₂O₃

Peso molecular: 332.48

Ref: 4Z-P-245001

17a-Hydroxypregnenolone

CAS: 387-79-1

17a-Hydroxypregnenolone is a pregnane steroid. It is a prohormone in the formation of dehydroepiandrosterone (DHEA).

Fórmula: C₂₁H₃₂O₃

Pureza: 99.38% - 99.76%

Forma y color: Solid

Peso molecular: 332.48

Ref: TM-T10048

17-Hydroxy Pregnenolone

Producto controlado

CAS: 387-79-1

Applications 17-Hydroxy Pregnenolone, is a metabolite of Pregnenolone (P712200).
References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),

Fórmula: C₂₁H₃₂O₃

Forma y color: White To Off-White

Peso molecular: 332.48

Ref: TR-H952320

17alpha-Hydroxypregnenolone

Producto controlado

CAS: 387-79-1

17alpha-Hydroxypregnenolone is a steroid hormone that has been shown to have effects on the metabolism of lipids, glucose and protein. This compound is synthesized from progesterone by the enzyme 17alpha-hydroxylase and is converted to 17beta-hydroxyprogesterone by the enzyme 17,20 lyase. It has been shown to have an effect on body mass index in humans and model organisms such as mice. The tissue culture studies showed that 17alpha-Hydroxypregnenolone led to an increase in serum bile acids. In adrenocortical carcinoma cell lines, this compound was found to inhibit the growth of cancer cells through inhibition of DNA synthesis and protein synthesis through inhibition of RNA polymerase II activity. It also inhibits infectious diseases by decreasing virus production and increasing the production of interferon alpha. When synthesized for use in experimental models, this compound can be used as a marker for metabolic disorders or cation

Fórmula: C₂₁H₃₂O₃

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 332.48 g/mol

Ref: 3D-FH40258

17-Hydroxy Pregnenolone

CAS: 387-79-1

Fórmula: C₂₁H₃₂O₃

Peso molecular: 332.48

Ref: ST-EA-CP-P135004