CAS 38916-34-6

somatostatina

Descripción:

somatostatina es una hormona peptídica compuesta por 14 aminoácidos, conocida principalmente por su papel en la inhibición de la secreción de varias otras hormonas, incluyendo la hormona del crecimiento y la insulina. Se produce en varios tejidos, notablemente en el hipotálamo y el tracto gastrointestinal. somatostatina funciona como una hormona reguladora, desempeñando un papel crucial en el sistema endocrino al modular la actividad de otras hormonas y neurotransmisores. Su número CAS, 38916-34-6, lo identifica de manera única en bases de datos químicas. La sustancia se caracteriza por su vida media relativamente corta en circulación, lo que requiere una administración cuidadosa en contextos terapéuticos. Los análogos de somatostatina se utilizan a menudo en entornos clínicos para manejar condiciones como la acromegalia, ciertos tipos de tumores y trastornos gastrointestinales. El péptido exhibe un alto grado de especificidad en su acción, uniéndose a los receptores de somatostatina, que están distribuidos por todo el cuerpo, influyendo en varios procesos fisiológicos. En general, somatostatina es un componente vital de la regulación hormonal, con implicaciones significativas tanto para la salud como para el manejo de enfermedades.

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

InChI: InChI=1/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)

Sinónimos:

• 1: PN: US20020156010 PAGE: 3 unclaimed protein
• 15: PN: WO2007081792 SEQID: 30 claimed protein
• 15-28-Somatostatin-28
• 243: PN: EP1170021 SEQID: 2 claimed protein
• 34: PN: WO2007058336 SEQID: 34 claimed protein
• Cyclic growth hormone release-inhibiting hormone
• Cyclic ovine somatostatin
• Cyclic somatostatin
• Cyclic somatostatin-14
• Cyclic somatotropin release-inhibitor factor
• Cyclic tetradecapeptide somatostatin
• Lampetra fluviatilis somatostatin-14
• Somatostatin
• Somatostatin (Amphiuma tridactylum)
• Somatostatin (Anguilla anguilla)
• Somatostatin (Gopherus agassizii)
• Somatostatin (human)
• Somatostatin (Lophius americanus)
• Somatostatin (Myxine glutinosa)
• Somatostatin (pigeon)
• Somatostatin (rat)
• Somatostatin (sheep reduced), cyclic (3→14)-disulfide
• Somatostatin I (Lophius americanus)
• Somatostatin SS-14
• Somatostatin-14 (Gopherus agassizii)
• Somatostatin-14 (sheep)
• Somatostatina
• Somatostatine
• Sr 9357
• Sst 14
• Stilamin
• Synthetic cyclic growth hormone release-inhibiting factor
• Synthetic cyclic growth hormone release-inhibiting hormone
• Synthetic growth hormone release-inhibiting hormone
• Synthetic somatostatin-14
• Somatostatin 14
• Somatostatin Acetate
• somatostatin gamma-irradiated*cell culture tested
• H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bond)
• alanyl-N-[19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide

Somatostatin 14

CAS: 38916-34-6

For cellular and molecular biology applications

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Peso molecular: 1637.89

Ref: 02-J66168

Somatostatin-14

CAS: 38916-34-6

Somatostatin-14 (SRIF) was originally isolated from ovine hypothalamic extracts on the basis of its ability to inhibit the secretion of radioimmunoassayable growth hormone by primary cultures of enzymatically dispersed rat anterior pituitary cells. SRIF is a small cyclic neuropeptide hormone with broad inhibitory effects on endocrine secretions such as the production of GH, glucagon, and insulin.

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Pureza: 99.7%

Forma y color: White Powder

Peso molecular: 1637.9

Ref: 01-4033009

SOMATOSTATIN CRS

CAS: 38916-34-6

SOMATOSTATIN CRS

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Peso molecular: 1637.878

Ref: 41-S0945000

Somatostatin acetate

CAS: 38916-34-6

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Peso molecular: 1637.89

Ref: 7W-GM7474

Somatostatin Diacetate

CAS: 38916-34-6

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂·2C₂H₄O₂

Peso molecular: 1637.90 2*60.05

Ref: 4Z-PS-219001

Somatostatin Acetate

CAS: 38916-34-6

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Pureza: 95%~99%

Forma y color: White to Off-white Powder

Peso molecular: 1637.88

Ref: BP-BPPG058

Somatostatin Acetate

CAS: 38916-34-6

Applications Growth hormone-release inhibiting factor; treatment of severe, acute hemorrhage of gastroduodenal ulcers; experimental antidiabetic.
References Brazeau, P., et al.: Science, 179, 77 (1973), Siler, T.M., et al.: J. Clin. Endocrinol. Metab., 37, 632 (1973), Pradayrol, L., et al.: Biochem. Biophys. Res. Commun., 85, 701 (1978), Mandarino, L., et al.: Nature, 291, 76 (1981),

Fórmula: C₇₈H₁₀₈N₁₈O₂₁S₂

Forma y color: Neat

Peso molecular: 1697.93

Ref: TR-S676750

Cyclic somatostatin

CAS: 38916-34-6

Cyclic somatostatin (SRIF-14) is a cyclic tetradecapeptide regulating many endocrine and nervous system functions.

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Pureza: 96.86%

Forma y color: Powder

Peso molecular: 1637.88

Ref: TM-TP1035

Somatostatin extrapure, 97%

CAS: 38916-34-6

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Pureza: min. 97%

Forma y color: White to off-white, Powder

Peso molecular: 1637.88

Ref: SR-54281

Somatostatin (Human, Ovine, Porcine, Rat, Mouse)

CAS: 38916-34-6

Somatostatin is a peptide hormone that has been found to inhibit pituitary growth hormone release as well as endocrine, pancreatic and GI secretions. It is widely expressed throughout the body for example in the gastrointestinal (GI) tract, hypothalamus, pancreas and the central nervous system. In the central nervous system somatostatin plays a role in neurotransmission modification and it has also demonstrated to be effective against a number of cancers such as squamous carcinoma. This product contains disulfide bonds between Cys3-Cys14 and is available as a 0.5mg vial.

Fórmula: C₇₆H₁₀N₁₈O₁₉S₂

Pureza: Min. 95%

Peso molecular: 1,637.9 g/mol

Ref: 3D-PSI-4023-V

Somatostatin

CAS: 38916-34-6

Somatostatin is a peptide hormone that is produced by the hypothalamus and inhibits the release of growth hormones, stimulates the release of insulin from the pancreas, and inhibits the release of glucagon from the pancreas. Somatostatin also has biological properties that inhibit neuronal death in combination therapy groups. It has been shown to have cell factor activity which may contribute to its antitumor activity. Somatostatin also has pro-apoptotic properties in vitro assays at physiological levels, making it an excellent target for cancer therapy.

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Pureza: Min. 95%

Peso molecular: 1,637.9 g/mol

Ref: 3D-HOR-299

Somatostatin

CAS: 38916-34-6

Somatostatin is a polypeptide hormone that is produced by the body to inhibit the release of other hormones in the body. It has also been used to treat diseases such as carcinoid syndrome, intestinal disorders, and diabetes mellitus type I. Somatostatin binds to somatostatin receptors on cells, which leads to inhibition of cell growth and secretion of hormones. Somatostatin has been shown to block basic protein synthesis and energy metabolism in rat liver cells. Its receptor activity is mediated by binding with signal peptide sequences and response elements.

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 1,637.88 g/mol

Ref: 3D-FS27855

Cyclic Somatostatin

CAS: 38916-34-6

Fórmula: C₇₆H₁₀₄N₁₈O₁₉S₂

Pureza: 97%

Forma y color: Liquid

Peso molecular: 1637.8781599999995

Ref: IN-DA00IMLT