CAS 3902-71-4

Trimetilpsoraleno

Descripción:

Trimetilpsoraleno (TMP) es un compuesto químico que pertenece a la clase de los psoralenos, conocidos por su capacidad para intercalarse con el ADN y formar enlaces cruzados al exponerse a la luz ultravioleta (UV). Se caracteriza por su estructura molecular, que incluye tres grupos metilo unidos al núcleo del psoraleno, lo que mejora su solubilidad y reactividad. TMP es típicamente un sólido cristalino incoloro a amarillo pálido y es soluble en disolventes orgánicos como el etanol y el dimetilsulfóxido (DMSO), pero tiene una solubilidad limitada en agua. Este compuesto se utiliza principalmente en fototerapia, particularmente para tratar afecciones cutáneas como la psoriasis y el vitiligo, ya que potencia los efectos de la terapia con luz UV. Además, TMP tiene aplicaciones en investigación, especialmente en estudios que involucran interacciones del ADN y fotobiología. Debido a sus propiedades fotosensibilizantes, se recomienda precaución al manipular TMP, ya que puede causar sensibilización de la piel y otros efectos adversos al exponerse a la luz UV.

Fórmula: C₁₄H₁₂O₃

InChI: InChI=1S/C14H12O3/c1-7-4-12(15)17-14-9(3)13-10(6-11(7)14)5-8(2)16-13/h4-6H,1-3H3

Clave InChI: InChIKey=FMHHVULEAZTJMA-UHFFFAOYSA-N

SMILES: CC=1C2=C(C=C3C1OC(C)=C3)C(C)=CC(=O)O2

Sinónimos:

• 5-Benzofuranacrylic acid, 6-hydroxy-β,2,7-trimethyl-, δ-lactone
• 4,5′,8-Trimethylpsoralen
• 2,5,9-Trimethyl-7H-furo[3,2-g][1]benzopyran-7-one
• Trioxsalen
• 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-

Trioxsalen

CAS: 3902-71-4

Fórmula: C₁₄H₁₂O₃

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 228.25

Ref: 3B-T2267

4,5',8-Trimethylpsoralen, 99%

CAS: 3902-71-4

4,5',8-Trimethylpsoralen is used for treatment of psoriasis, and as a photochemical crosslinker of DNA used as a probe for nucleic acid structure, used to crosslink DNA onto mica surfaces, mutagenesis of N2 worms. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar p

Fórmula: C₁₄H₁₂O₃

Pureza: 99%

Peso molecular: 228.25

Ref: 02-J63226

TRIOXSALEN

CAS: 3902-71-4

Fórmula: C₁₄H₁₂O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 228.2433

Ref: IN-DA003V59

Trioxsalen

CAS: 3902-71-4

Trioxsalen

Pureza: 98%

Peso molecular: 228.25g/mol

Ref: 54-OR1024247

Trioxsalen

CAS: 3902-71-4

Trioxsalen

Pureza: ≥98%

Peso molecular: 228.24g/mol

Ref: 54-BUP13950

Trioxsalen

CAS: 3902-71-4

Fórmula: C₁₄H₁₂O₃

Peso molecular: 228.25

Ref: 7W-GL4271

Trioxysalen

CAS: 3902-71-4

Fórmula: C₁₄H₁₂O₃

Forma y color: Neat

Peso molecular: 228.24

Ref: 04-C17892400

Trioxsalen

CAS: 3902-71-4

Fórmula: C₁₄H₁₂O₃

Peso molecular: 228.25

Ref: 4Z-T-434001

Trioxsalen

CAS: 3902-71-4

Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema.

Fórmula: C₁₄H₁₂O₃

Pureza: 98.96% - 99.41%

Forma y color: Crystalline Powder

Peso molecular: 228.24

Ref: TM-T4558

Trioxsalen

CAS: 3902-71-4

Lactone

Fórmula: C₁₄H₁₂O₃

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 228.25

Ref: 5G-80322

2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one

CAS: 3902-71-4

Pureza: 99.0%

Forma y color: Solid

Peso molecular: 228.2469940185547

Ref: 10-F358125

Trioxysalen

Producto controlado

CAS: 3902-71-4

Applications Trioxysalen, is used for visualization of genomic interstrand cross-links localized by laser photoactivation. It has been also been used to crosslink DNA onto mica surfaces.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Thazhathveetill, et al.: Bioconjugare Chem., 18 (2), 431 (2007); Musdal, Y., et al.: Chem. Bio. Interac., 205, 53 (2013);

Fórmula: C₁₄H₁₂O₃

Forma y color: Neat

Peso molecular: 228.24

Ref: TR-T806580

4,5',8-Trimethylpsoralen

CAS: 3902-71-4

4,5',8-Trimethylpsoralen is a fatty acid that can be synthesized from para-aminobenzoic acid. It has been shown to have carcinogenic potential in vitro and in vivo. 4,5',8-Trimethylpsoralen inhibits transcription by binding to DNA polymerase II and III. This inhibition prevents the production of RNA and protein synthesis, leading to cell death. 4,5',8-Trimethylpsoralen also inhibits DNA synthesis by binding to the enzyme DNA gyrase and topoisomerase IV. It is not active against some bacteria that are resistant to other drugs due to the presence of mutations in their genes encoding for the target enzymes. 4,5',8-Trimethylpsoralen has been shown to inhibit autoimmune diseases such as arthritis and lupus erythematosus.br>br>4,5',8-Trimethylpsoralen is most commonly used as

Fórmula: C₁₄H₁₂O₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 228.24 g/mol

Ref: 3D-FT47227

Trioxsalen (DISCONTINUED)

CAS: 3902-71-4

Aromatic heterocyclic pesticides with oxygen hetero-atom(s) only, nesoi

Fórmula: C₁₄H₁₂O₃

Forma y color: White Crystals

Peso molecular: 228.07864

Ref: 45-1693009