CAS 4084-27-9

3-Desoxiglucosona

Descripción:

3-Desoxiglucosona (3-DG) es un compuesto dicarbonílico reactivo derivado del metabolismo de la glucosa. Se caracteriza por su estructura, que presenta un grupo funcional cetona y un grupo funcional aldehído, lo que lo convierte en un potente precursor en la formación de productos finales de glicación avanzada (AGEs). Estos AGEs están implicados en diversas condiciones patológicas, incluyendo la diabetes y las enfermedades cardiovasculares. Se conoce que el 3-DG tiene la capacidad de reaccionar con aminoácidos, proteínas y ácidos nucleicos, lo que lleva a modificaciones que pueden afectar la función celular y contribuir al estrés oxidativo. El compuesto suele estar presente en cantidades traza en los sistemas biológicos y puede formarse a través de procesos de glicación no enzimática. Su reactividad y efectos biológicos potenciales lo convierten en un tema de interés en la investigación relacionada con trastornos metabólicos y el envejecimiento. Además, 3-Desoxiglucosona puede ser analizado utilizando diversas técnicas, incluyendo cromatografía y espectrometría de masas, para estudiar su papel en la salud y la enfermedad.

Fórmula: C₆H₁₀O₅

InChI: InChI=1S/C6H10O5/c7-2-4(9)1-5(10)6(11)3-8/h2,5-6,8,10-11H,1,3H2/t5-,6+/m0/s1

Clave InChI: InChIKey=ZGCHLOWZNKRZSN-NTSWFWBYSA-N

SMILES: [C@H](CC(C=O)=O)([C@@H](CO)O)O

Sinónimos:

• 2-keto-3-Deoxyglucose
• 3-Deoxy-<span class="text-smallcaps">D</span>-erythro-hexos-2-ulose
• 3-Deoxy-<span class="text-smallcaps">D</span>-erythro-hexosulose
• 3-Deoxy-<span class="text-smallcaps">D</span>-glucosone
• 3-Deoxyglucosone
• <span class="text-smallcaps">D</span>-erythro-Hexos-2-ulose, 3-deoxy-
• <span class="text-smallcaps">D</span>-erythro-Hexosulose, 3-deoxy-
• D-erythro-hexos-2-ulose, 3-deoxy-
• 3-Deoxy-D-erythro-hexosulose
• D-erythro-Hexosulose, 3-deoxy-
• 3-Deoxy-D-erythro-hexos-2-ulose

3-Deoxy-D-glucosone, 95%

CAS: 4084-27-9

Frequently used as a reference for the analysis and detection of glucose degradation products and glycating agents. Also used for cross-linking studies as it readily reacts with protein amino groups. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfol

Fórmula: C₆H₁₀O₅

Pureza: 95%

Forma y color: Yellow, Powder or crystals or crystalline powder

Peso molecular: 162.14

Ref: 02-J66223

3-deoxy Glucosone

CAS: 4084-27-9

Fórmula: C₆H₁₂O₅

Pureza: 75%

Forma y color: Solid

Peso molecular: 164.1565

Ref: IN-DA00744B

3-Deoxy-D-glucosone

CAS: 4084-27-9

3-Deoxy-D-glucosone

Fórmula: C₆H₁₀O₅

Pureza: >95%

Forma y color: yellow amorphous solid

Peso molecular: 162.14g/mol

Ref: 54-BICL4267

3-Deoxy-D-erythro-hexos-2-ulose

CAS: 4084-27-9

3-Deoxy-D-erythro-hexos-2-ulose

Pureza: ≥95%

Forma y color: Pale Yellow Solid

Peso molecular: 162.14g/mol

Ref: 54-OR3915T

3-Deoxyglucosone

CAS: 4084-27-9

3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein

Fórmula: C₆H₁₀O₅

Pureza: 95%

Forma y color: Solid

Peso molecular: 162.14

Ref: TM-T19117

Fructose Glycerol Derivative 6 (3-Deoxyglucosone)

CAS: 4084-27-9

Fórmula: C₆H₁₀O₅

Peso molecular: 162.14

Ref: 4Z-F-161011

3-Deoxyglucosone

CAS: 4084-27-9

Fórmula: C₆H₁₀O₅

Pureza: One spot

Forma y color: Pale yellow to yellow powder or solid

Peso molecular: 162.14

Ref: 7W-GC0945

3-Deoxyglucosone

CAS: 4084-27-9

Stability Hygroscopic, Light Sensitive, Temperature Sensitive
Applications An intermediate in the Maillard reaction of proteins with glucose, which is metabolised to 3-Deoxyfructose. An intermediate in the formation of pyrraline, which might contribute to a pathological effect, such as carcinogenesis.
References Kato, H. et al.: Agric. Biol. Chem., 51, 683 (1987), Hayase, F. et al.: J. Biol. Chem., 264, 3758 (1989), Kato, H. et al.: Biochimica et Biophysica Acta, 1035, 71 (1990)

Fórmula: C₆H₁₀O₅

Forma y color: White To Yellow

Peso molecular: 162.14

Ref: TR-D239150

3-Deoxy-D-glucosone

CAS: 4084-27-9

3-Deoxy-D-glucosone is a compound that belongs to the group of monosaccharides and has a basic structure. It can be found in many types of biological samples, including blood. The x-ray diffraction data for 3-deoxy-D-glucosone shows an asymmetric unit of two molecules with a coordination geometry of 2.3. This compound is known to have high protein oxidation rates, which are caused by dna binding activity. 3-Deoxyglucosone has been shown to be involved in the pathogenic mechanism of many types of cancers.

Fórmula: C₆H₁₀O₅

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 162.14 g/mol

Ref: 3D-MD06669