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CAS 41078-70-0
:3-(2-cloroetil)-2-metil-4H-pirido[1,2-a]pirimidin-4-ona
Descripción:
3-(2-cloroetil)-2-metil-4H-pirido[1,2-a]pirimidin-4-ona, con el número CAS 41078-70-0, es un compuesto orgánico heterocíclico caracterizado por su estructura de pirido-pirimidina. Este compuesto presenta un grupo cloroetilo, que contribuye a su reactividad y potencial actividad biológica. La presencia del grupo metilo mejora su lipofilia, lo que puede influir en sus propiedades farmacocinéticas. Típicamente, los compuestos de esta clase pueden exhibir diversas actividades biológicas, incluyendo propiedades antimicrobianas o anticancerígenas, debido a su capacidad para interactuar con objetivos biológicos como enzimas o receptores. La estructura molecular sugiere que puede participar en enlaces de hidrógeno y otras interacciones, que son cruciales para su función biológica. Además, la estabilidad y solubilidad del compuesto pueden variar según las condiciones ambientales, como el pH y la polaridad del disolvente. En general, 3-(2-cloroetil)-2-metil-4H-pirido[1,2-a]pirimidin-4-ona representa una clase de compuestos que pueden tener implicaciones significativas en la química medicinal y el desarrollo de fármacos.
Fórmula:C11H11ClN2O
InChI:InChI=1S/C11H11ClN2O/c1-8-9(5-6-12)11(15)14-7-3-2-4-10(14)13-8/h2-4,7H,5-6H2,1H3
Clave InChI:InChIKey=LFTGLYCNMGGMKL-UHFFFAOYSA-N
SMILES:O=C1N2C(=NC(C)=C1CCCl)C=CC=C2
Sinónimos:- 3-(2-Chloroethyl)-2-Methylpyrido[1,2-A]Pyrimidin-4-One
- 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-2-methyl-
- 3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
- :3-(2-chloroethyl)-2-methyl-4h-pyrido-[1,2-a]pyrimidin-4-one
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Encontrado 9 productos.
3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Fórmula:C11H11ClN2OPureza:98%Forma y color:SolidPeso molecular:222.67083-(2-Chloroethyl)-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One
CAS:3-(2-Chloroethyl)-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-OnePureza:98%Peso molecular:222.67g/molRisperidone Impurity 3
CAS:Fórmula:C11H11ClN2OForma y color:White To Off-White SolidPeso molecular:222.673-(2-Chloro-ethyl)-2-methyl-pyrido[1,2-a]pyrimidin-4-one
CAS:Fórmula:C11H11ClN2OPureza:98%Forma y color:SolidPeso molecular:222.673-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>Applications An intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, T., et al.: J. Med. Chem., 33, 527 (1990), Yapi, A., et al.: Chem. Pharm. Bull., 48, 1886 (2000), Yapi, A., et al.: Arch. Pharm., 339, 201 (2006); Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988); Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990); Green, B.: Curr. Med. Res. Opin., 16, 57 (2000);<br></p>Fórmula:C11H11ClN2OForma y color:NeatPeso molecular:222.673-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a chemical compound that is used to synthesize the drug paliperidone. The reaction time of this synthesis reaction is high and the yield is high. The conformation of the product can be predicted with theory. The hydrochloride salt of the product has a higher solubility in water than does the free base form. The reactants are 3-(2-chloroethyl) pyridine and 2-methyl 4H pyrido[1,2-a]pyrimidin-4-one, which are both cheap and easily accessible. This synthesis can be carried out using solvents such as phosphorus oxychloride or carbonyl oxychloride. The dihedral angle for this molecule is around 100 degrees, which makes it a planar molecule. This compound reacts with pyridine</p>Fórmula:C11H11ClN2OPureza:Min. 95%Peso molecular:222.67 g/mol3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Fórmula:C11H11ClN2OPureza:>98.0%(GC)(T)Forma y color:White to Light yellow powder to crystalPeso molecular:222.67
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0073CI.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR1010637.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0491.29-0025.jpg&w=3840&q=75)
![3-(2-Chloro-ethyl)-2-methyl-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF036503.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FC366150.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FFC20228.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FC2716.jpg&w=3840&q=75)
