CAS 41294-56-8

Alfacalcidol

Descripción:

Alfacalcidol, con el número CAS 41294-56-8, es un análogo sintético de la vitamina D, específicamente una forma de vitamina D3 (colecalciferol). Se utiliza principalmente en el tratamiento de condiciones relacionadas con el metabolismo del calcio, como la osteoporosis y la osteodistrofia renal. Alfacalcidol se caracteriza por su capacidad para mejorar la absorción intestinal de calcio y fosfato, promoviendo así la salud ósea. Es un compuesto liposoluble, lo que significa que es soluble en lípidos y puede almacenarse en la grasa corporal. La sustancia se administra típicamente en su forma activa, lo que permite un efecto más rápido en comparación con otros compuestos de vitamina D que requieren conversión en el hígado y los riñones. Alfacalcidol se prefiere a menudo en pacientes con insuficiencia renal, ya que elude la necesidad de activación renal. Sus efectos farmacológicos incluyen la regulación de la homeostasis del calcio y la modulación del metabolismo óseo, lo que lo convierte en un agente terapéutico importante en el manejo de diversas enfermedades metabólicas óseas.

Fórmula: C₂₇H₄₄O₂

InChI: InChI=1/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23+,24-,25?,26-,27-/m1/s1

Clave InChI: InChIKey=OFHCOWSQAMBJIW-AVJTYSNKSA-N

SMILES: C[C@@]12[C@](\C(=C\C=C\3/C(=C)[C@@H](O)C[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]

Sinónimos:

• (1Alpha,3Beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-Triene-1,3-Diol
• (1Alpha,3Beta,5Z,7E)-Secocholesta-5,7,10(19)-Triene-1,3-Diol
• (1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
• (1R,3S,5Z,7E,14xi)-9,10-secocholesta-5,7,10-triene-1,3-diol
• (1S)-Hydroxycalciol
• (1S,3R,5E,7Z)-9,10-secocholesta-5,7,10-triene-1,3-diol
• (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3-diol
• 1(Alpha)-Hydroxyvitamin D3
• 1,2-Hydroxy Cholecalciferol
• 1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3R)-
• 1-Alpha-Hydroxycholecalciferol
• 1-Alpha-Hydroxyvitamin D
• 1-Hydroxycholecalciferol
• 1-Hydroxyvitamin D3
• 1-Hydroxyvitamin D₃
• 1-Hydroxyvitamind3
• 1-Α-Hydroxycholecalciferol
• 1Alpha-Oh-D3
• 1α(OH)D3
• 1α(OH)D₃
• 1α-Hydroxycholecalciferol
• 1α-Hydroxyvitamin D3
• 1α-Hydroxyvitamin D₃
• 7,10(19)-Triene-1,3-Diol,(1-Alpha,3-Beta,5Z,7E)-10-Secocholesta-5
• 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, (1α,3β,5Z,7E)-
• Alfacaicidol
• Alfacalcidol
• Alfarol
• Alpha Calcidol
• Alpha D3
• Alpha D₃
• Alpha-Hcl
• Alpharol
• Bondiol
• EinsAlpha
• Etalpha
• Hydroxyvitamin D3
• Oxydevit
• Tevabone
• Vitamin d3, 1alpha-hydroxy-
• α-Calcidol
• ALPHACALCIDOL
• 1(ALPHA)-HYDROXYVITAMIN D3 97+% HPLC
• 1-alpha-Hydroxycholecalciferol(1alpha,3beta,5Z,7E)-Secocholesta-5,7,10(19)-trie

Alfacalcidol

CAS: 41294-56-8

Fórmula: C₂₇H₄₄O₂

Pureza: >95.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 400.65

Ref: 3B-A3125

ALFACALCIDOL CRS

CAS: 41294-56-8

ALFACALCIDOL CRS

Ref: 41-A0325450

ALFACALCIDOL FOR SYSTEM SUITABILITY A CRS

CAS: 41294-56-8

ALFACALCIDOL FOR SYSTEM SUITABILITY A CRS

Forma y color: Powder

Ref: 41-Y0002125

Alfacalcidol

CAS: 41294-56-8

Fórmula: C₂₇H₄₄O₂

Peso molecular: 400.65

Ref: 4Z-A-401001

Alfacalcidol

CAS: 41294-56-8

Fórmula: C₂₇H₄₄O₂

Pureza: 97.0 - 102.0 %

Forma y color: White crystalline powder

Peso molecular: 400.6

Ref: 7W-GP9489

Alfacalcidol

CAS: 41294-56-8

Alfacalcidol

Pureza: ≥98%

Peso molecular: 400.64g/mol

Ref: 54-BUP02065

1a-hydroxy Vitamin D3

CAS: 41294-56-8

Fórmula: C27H44O2

Pureza: >95%

Forma y color: Solid

Peso molecular: 400.64

Ref: 48-60-1476

Alfacalcidol

Producto controlado

CAS: 41294-56-8

Fórmula: C₂₇H₄₄O₂

Forma y color: Neat

Peso molecular: 400.64

Ref: 86-MM3002.00

Alfacalcidol

CAS: 41294-56-8

Alfacalcidol (Etalpha) (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.

Fórmula: C₂₇H₄₄O₂

Pureza: 99.38%

Forma y color: Solid

Peso molecular: 400.64

Ref: TM-T6374

Alfacalcidol-d7

CAS: 41294-56-8

Fórmula: C₂₇H₃₇D₇O₂

Peso molecular: 407.69

Ref: 4Z-A-401005

Alfacalcidol

Producto controlado

CAS: 41294-56-8

Stability Light and Temperature Sensitive
Applications A synthetic analog of Calcitiol (the hormonal form of vitamin D3), which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Fórmula: C₂₇H₄₄O₂

Forma y color: Off White

Peso molecular: 400.64

Ref: TR-A524000

Alfacalcidol

CAS: 41294-56-8

Alfacalcidol is a form of vitamin D that is used to treat metabolic disorders such as hypocalcemia and hypoparathyroidism. It is a potent inducer of enzymes in the liver, which convert vitamin D into its active form. Alfacalcidol has been shown to be effective in the treatment of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. Alfacalcidol has also been shown to have calcium-regulating properties in the body. This drug may also be used for the treatment of congestive heart failure, high blood pressure, and diabetes mellitus type 2. Alfacalcidol is metabolized by hydroxylation to 25-hydroxycalcifediol and then to calcitriol, which binds with calcium ions in order to regulate serum calcium levels. This drug can be administered orally or intravenously.

Fórmula: C₂₇H₄₄O₂

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 400.64 g/mol

Ref: 3D-FA17275

Alfacalcidol-d7

Producto controlado

CAS: 41294-56-8

Fórmula: C₂₇D₇H₃₇O₂

Forma y color: Neat

Peso molecular: 407.68

Ref: TR-A524002

Alfacalcidol

CAS: 41294-56-8

Forma y color: Neat

Ref: 61-FOR3002.00