CAS 42946-36-1

9-Oxo-9,10-dihydroacridine-2-carboxylic acid

CAS: 42946-36-1

9-Oxo-9,10-dihydroacridine-2-carboxylic acid is a fatty acid oxidation product that has been shown to induce apoptosis in the mitochondria of tumor cells. This process is mediated by the release of cytochrome c from the mitochondria into the cytosol. It also binds to antigens in the extracellular matrix and induces autoantibodies against these antigens. 9-Oxo-9,10-dihydroacridine-2-carboxylic acid has been found to bind to caspase family members and potentiate their activity. 9oxoacridine 2 carboxylic acid is also a potential antitumor agent that shows histological evidence of tumor regression in rats injected with sarcoma 180 cells.
9oxoacridine 2 carboxylic acid also binds to DNA and inhibits protein synthesis by blocking transcriptional initiation at G

Fórmula: C₁₄H₉NO₃

Pureza: Min. 95%

Peso molecular: 239.23 g/mol

Ref: 3D-SBA94636