CAS 43200-80-2

Zopiclona

Descripción:

Zopiclona es un agente hipnótico no benzodiazepínico utilizado principalmente para el tratamiento del insomnio. Pertenece a la clase de compuestos de ciclopirrolona y se caracteriza por sus propiedades sedantes y ansiolíticas. La fórmula química de Zopiclona es C17H17ClN6O3, y presenta una estructura única que incluye un anillo de pirrolona, que contribuye a sus efectos farmacológicos. Zopiclona actúa sobre el sistema nervioso central al aumentar la actividad del ácido gamma-aminobutírico (GABA), un neurotransmisor que promueve el sueño y la relajación. Se administra típicamente en forma de tabletas y es conocido por su rápido inicio de acción, lo que lo hace efectivo para el manejo a corto plazo de los trastornos del sueño. Los efectos secundarios comunes pueden incluir somnolencia, mareos y posible dependencia con el uso prolongado. Debido a sus efectos sedantes, se aconseja precaución al operar maquinaria o conducir después de tomar Zopiclona. Al igual que con cualquier medicamento, es importante usar Zopiclona bajo la guía de un profesional de la salud para mitigar riesgos y garantizar un uso seguro.

Fórmula: C₁₇H₁₇ClN₆O₃

InChI: InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3

Clave InChI: InChIKey=GBBSUAFBMRNDJC-UHFFFAOYSA-N

SMILES: O(C(=O)N1CCN(C)CC1)C2N(C(=O)C=3C2=NC=CN3)C4=CC=C(Cl)C=N4

Sinónimos:

• (.+-.)-Zopiclone
• 5H-Pyrrolo[3,4-b]pyrazine, 1-piperazinecarboxylic acid deriv.
• Amoban
• Amovane
• Hypnor
• Imoclone
• Imovance
• Imovane
• Rp 27267
• Sopivan
• Zimovane
• Zopiclon
• Zopiclona
• 1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
• 4-({[(5R)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl]oxy}carbonyl)-1-methylpiperazin-1-ium
• 4-({[(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl]oxy}carbonyl)-1-methylpiperazin-1-ium
• 4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
• 27267r.p.
• 27267 R.P.
• 4-methyl-,6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-1-piperazinecarboxylicaci
• 4-Methyl-1-piperazinecarboxylic acid ester with 6-(5-chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one
• Zopicclone
• 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate
• 4-Methyl-1-piperazine-carboxylic Acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl Ester
• 4-METHYLPIPERAZINE-1-CARBOXYLIC ACID 6-(5-CHLORO-PYRIDIN-2-YL)-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-B]PY

Zopiclone 1.0 mg/ml in Acetonitrile

CAS: 43200-80-2

Forma y color: Single Solution

Ref: 61-AMP0149.00-11

Zopiclone

CAS: 43200-80-2

Forma y color: Neat

Ref: 61-FOR0149.00

Zopiclone, 1mg/ml in Acetonitrile

CAS: 43200-80-2

Forma y color: Single Solution

Ref: LP-ZOP-921-FB-1LA

Zopiclone

Producto controlado

CAS: 43200-80-2

Forma y color: Neat

Ref: LP-ZOP-921-FB-10

Zopiclone

CAS: 43200-80-2

Fórmula: C₁₇H₁₇ClN₆O₃

Peso molecular: 388.81

Ref: 4Z-Z-0637

Zopiclone

CAS: 43200-80-2

Fórmula: C₁₇H₁₇ClN₆O₃

Peso molecular: 388.81

Ref: 7W-GP1081

(±)-Zopiclone-d3 (N-methyl-d3)

Producto controlado

CAS: 1398066-10-8, 43200-80-2

Pureza: 99 atom % D

Forma y color: White Solid

Peso molecular: 391.83

Ref: 3U-D7385

Zopiclone

CAS: 43200-80-2

Forma y color: White To Off-White

Ref: 86-MM0149.00

Zopiclone

Producto controlado

CAS: 43200-80-2

Fórmula: C₁₇H₁₇ClN₆O₃

Forma y color: Neat

Peso molecular: 388.81

Ref: 04-C17978000

Zopiclone-d4

CAS: 43200-80-2

Fórmula: C₁₇H₁₃D₄ClN₆O₃

Peso molecular: 392.84

Ref: 4Z-Z-0615

Zopiclone

Producto controlado

CAS: 43200-80-2

Stability Hygroscopic
Applications Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic.
References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),

Fórmula: C₁₇H₁₇ClN₆O₃

Forma y color: White To Off-White

Peso molecular: 388.81

Ref: TR-Z700500

Zopiclone

Producto controlado

CAS: 43200-80-2

Zopiclone is a benzodiazepine that has been shown to have potent inducers of hepatic enzymes. It is used for the treatment of insomnia, but long-term use may lead to tolerance and dependence. Zopiclone binds to the receptor site for GABA, which is a neurotransmitter. It also affects other neurotransmitters such as monoamines, which are involved in mood control and arousal. Zopiclone has been shown to be beneficial in patients with congestive heart failure, although it can cause orthostatic hypotension. The matrix effect of zopiclone is significant, leading to drug interactions with other drugs taken at the same time. Zopiclone has been shown to be effective in treating chronic insomnia and its long-term efficacy appears to be good.

Fórmula: C₁₇H₁₇ClN₆O₃

Peso molecular: 388.81 g/mol

Ref: 3D-W-106239

Zopiclone

Producto controlado

CAS: 43200-80-2

Antagonist of GABA(A); hypnotic agent

Fórmula: C₁₇H₁₇ClN₆O₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 388.81 g/mol

Ref: 3D-FZ156793

ZOPICLONE CRS - * PSY

Producto controlado

CAS: 43200-80-2

ZOPICLONE CRS - * PSY

Fórmula: C₁₇H₁₇ClN₆O₃

Forma y color: Powder

Peso molecular: 388.8083

Ref: 41-Z3000000

Zopiclone

Producto controlado

CAS: 43200-80-2

Zopiclone

Fórmula: C₁₇H₁₇CIN₆O₃

Pureza: 99.8%

Forma y color: White To Off-White

Peso molecular: 492.04069

Ref: 47-812

Zopiclone (1 mg/mL in Acetonitrile)

Producto controlado

CAS: 43200-80-2

Fórmula: C₁₇H₁₇ClN₆O₃

Forma y color: Colourless

Peso molecular: 388.81

Ref: TR-KIT0130