CAS 438-59-5

Clorhidrato de 10,11-didehidronortriptilina

Descripción:

Clorhidrato de 10,11-didehidronortriptilina es un compuesto químico que pertenece a la clase de los antidepresivos tricíclicos. Es un derivado de la nortriptilina, que es conocida por su uso en el tratamiento de la depresión y ciertos tipos de dolor. El compuesto presenta una estructura tricíclica, que se caracteriza por tres anillos interconectados, contribuyendo a su actividad farmacológica. Como sal de clorhidrato, es típicamente más soluble en agua, facilitando su uso en formulaciones farmacéuticas. El compuesto actúa principalmente inhibiendo la recaptación de neurotransmisores como la norepinefrina y la serotonina, mejorando así el estado de ánimo y aliviando los síntomas depresivos. Sus propiedades químicas incluyen un peso molecular específico y un punto de fusión definido, que son esenciales para su caracterización y control de calidad en aplicaciones farmacéuticas. Los perfiles de seguridad y eficacia son críticos, y al igual que otros antidepresivos tricíclicos, puede tener efectos secundarios, incluyendo sedación y efectos anticolinérgicos. El manejo y la dosificación adecuados son esenciales para minimizar los riesgos asociados con su uso.

Fórmula: C₁₉H₂₀ClN

InChI: InChI=1/C19H19N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-13,20H,6,14H2,1H3;1H

Clave InChI: InChIKey=UZMPCPFDZYTEJG-UHFFFAOYSA-N

SMILES: C(CCNC)=C1C=2C(C=CC=3C1=CC=CC3)=CC=CC2.Cl

Sinónimos:

• 1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-, hydrochloride (9CI)
• 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride
• 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride (1:1)
• 10,11-Didehydronortriptyline hydrochloride
• 10,11-thelda-Nortriptyline hydrochloride
• 3-(5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine hydrochloride (1:1)
• 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, N-methyl-, hydrochloride
• 5H-Dibenzo[a,d]cycloheptene-Δ^5,γ-propylamine, N-methyl-, hydrochloride
• N 7068 hydrochloride
• Norproheptatriene hydrochloride
• Ro 4-6011
• 3-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)propyl(methyl)ammonium chloride
• 5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, N-methyl-, hydrochloride
• Nortriptyline Impurity 2 (Nortriptyline EP Impurity B)
• Cyclobenzaprine USP RC B Q: What is the storage condition of
• 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine Hydrochloride
• Einecs 207-118-3
• Cyclobenzaprine USP RC B
• Desmethyl Cyclobenzaprine Hydrochloride
• 3-(5H-Dibenzo[a,d][7]annulen-5-ylid
• Cyclobenzaprine Related CoMpound B
• Cyclobenzaprine Impurity 2(Cyclobenzaprine USP RC B)
• Cyclobenzaprine USP Related Compound B as Hydrochloride
• N-desmethyl Cyclobenzaprine HCl (USP RC B)
• Nortriptyline EP Impurity B HCl
• Cyclobenzaprine impurity 2/Cyclobenzaprine USP Related Compound B/Desmethyl Cyclobenzaprine Hydrochloride/3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine hydrochloride
• NORTRIPTYLINE EP IMPURITY B
• Cyclobenzaprine USP RC B Q: What is the CAS Number of
• Nortriptyline EP Impurity B HCl (N-Desmethyl Cyclobenzaprine HCl)
• Nortriptyline Hydrochloride Impurity B as Hydrochloride
• N-Desmethyl Cyclobenzaprine
• 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N-methylpropan-1-amine
• N-Desmethyl Cyclobenzaprine Hydrochloride
• Nortriptyline Hydrochloride EP Impurity B as Hydrochloride
• Cyclobenzaprine USP Related Compound B
• Cyclobenzaprine DesMethyl HCl
• N-Desmethylcyclobenzaprine hydrochloride solution
• N-Desmethyl Cyclobenzaprine-d3
• Cyclobenzaprine Related Compound B (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine (1154525)
• Cyclobenzaprine Related Compound B (10 mg) (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, hydrochloride)
• Cyclobenzaprine USP RC B Q: What are the applications of
• Desmethylcyclobenzaprine hydrochloride salt
• Cyclobenzaprine USP RC BQ: What is
• Cyclobenzaprine Related Compound B as Hydrochloride

N-Desmethylcyclobenzaprine Hydrochloride (Norcyclobenzaprine Hydrochloride) 1.0 mg/ml in Methanol (as free base)

CAS: 438-59-5

Forma y color: Single Solution

Ref: 61-AMP0079.01-01

Cyclobenzaprine Related Compound B (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, hydrochloride)

CAS: 438-59-5

Aromatic monoamines and their derivatives, salts thereof, nesoi

Fórmula: C₁₉H₁₉N·HCl

Forma y color: White Powder

Peso molecular: 261.15175

Ref: 45-1154525

1-Propanamine,3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-,hydrochloride (1:1)

CAS: 438-59-5

Fórmula: C₁₉H₂₀ClN

Forma y color: Solid

Peso molecular: 297.8218

Ref: IN-DA0037GQ

Nortriptyline EP Impurity B HCl (Cyclobenzaprine USP Related Compound B, N-Desmethyl Cyclobenzaprine HCl)

CAS: 438-59-5

Fórmula: C₁₉H₁₉N·HCl

Peso molecular: 261.37 36.46

Ref: 4Z-N-3621

3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine Hydrochloride (Norcyclobenzaprine Hydrochloride)

Producto controlado

CAS: 438-59-5

Fórmula: C₁₉H₁₉N·ClH

Forma y color: Neat

Peso molecular: 297.82

Ref: 86-MM0079.01

Desmethyl Cyclobenzaprine Hydrochloride

CAS: 438-59-5

Impurity Cyclobenzaprine USP Related Compound B
Applications Desmethyl Cyclobenzaprine (Cyclobenzaprine USP Related Compound B) is a metabolite of Cyclobenzaprine.
References Wang, R.W., et al.: Drug Metab. Dispos., 24, 786 (1996),

Fórmula: C₁₉H₁₉N·ClH

Forma y color: Off-White

Peso molecular: 297.82

Ref: TR-D291560

Nortriptyline EP Impurity B

CAS: 438-59-5

Fórmula: C₁₉H₁₉NHCl

Peso molecular: 261.37 : 36.46

Ref: ST-EA-CP-N15002

Desmethyl cyclobenzaprine hydrochloride

CAS: 438-59-5

Desmethyl cyclobenzaprine hydrochloride is a metabolite of cyclobenzaprine, a drug used for the treatment of muscle spasms. Desmethyl cyclobenzaprine hydrochloride has been shown to have an increased potency for the termination of nerve impulses. These results were determined by in vivo studies using an assay on rat sciatic nerve and a study on human adrenergic receptors. This metabolite also shows potentiation effects with other drugs such as clonidine and prazosin, which are used to treat hypertension and anxiety, respectively. However, clinical relevance is still unknown due to the lack of data on desmethyl cyclobenzaprine hydrochloride's uptake and enhancement in humans.

Fórmula: C₁₉H₂₀ClN

Pureza: Min. 95%

Forma y color: White To Off-White Solid

Peso molecular: 297.82 g/mol

Ref: 3D-FD21256