CAS 444-29-1

1-Iodo-2-(trifluorometil)benceno

Descripción:

1-Iodo-2-(trifluorometil)benceno, con el número CAS 444-29-1, es un compuesto aromático caracterizado por la presencia de un átomo de yodo y un grupo trifluorometilo (-CF3) unido a un anillo de benceno. Este compuesto es típicamente un líquido incoloro a amarillo pálido con un olor distintivo. Se conoce por su densidad relativamente alta y baja solubilidad en agua, lo que lo hace más soluble en disolventes orgánicos. La presencia del grupo trifluorometilo confiere propiedades electrónicas únicas, mejorando su reactividad en varias reacciones químicas, particularmente en sustitución nucleofílica y sustitución aromática electrofílica. Además, el átomo de yodo puede actuar como un grupo saliente en reacciones, facilitando la síntesis de otros compuestos. Debido a su naturaleza halogenada, 1-Iodo-2-(trifluorometil)benceno puede exhibir actividad biológica y es de interés en química medicinal y ciencia de materiales. El manejo y almacenamiento adecuados son esenciales, ya que puede representar riesgos para la salud y el medio ambiente.

Fórmula: C₇H₄F₃I

InChI: InChI=1/C7H4F3I/c8-7(9,10)5-3-1-2-4-6(5)11/h1-4H

Clave InChI: InChIKey=IGZGUYVVBABKOY-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=C(I)C=CC=C1

Sinónimos:

• .alpha.,.alpha.,.alpha.-Trifluoro-o-iodo toluene
• 1-Iod-2-(trifluormethyl)benzol
• 1-Iodo-2-(trifluoromethyl)benzene
• 1-Trifluoromethyl-2-iodobenzene
• 2-(Trifluoromethyl)iodobenzene
• 2-Iodo-1-trifluoromethylbenzene
• 2-Iodobenzotrifluoride
• 2-Trifluoromethylphenyl iodide
• Benzene, 1-iodo-2- (trifluoromethyl)-
• NSC 88291
• Toluene, alpha,alpha,alpha-trifluoro-o-iodo-
• Toluene, α,α,α-trifluoro-o-iodo-
• alpha,alpha,alpha-Trifluoro-2-iodotoluene
• o-(Trifluoromethyl)iodobenzene
• o-Iodobenzotrifluoride
• o-Trifluoromethyliodobenzene
• α,α,α-Trifluoro-o-iodotoluene
• 2-(Trifluoromethyl)iodobenzene, 2-Iodo-α,α,α-trifluorotoluene
• 2-Trifluoromethyliodobenzene
• 2-Iodobenztrifluoride
• 2-Iodobenzotrifluoride (stabilized with Copper chip)
• 2-IODOBENZOTRIFLUORIDE 99%
• alpha,alpha,alpha-Trifluoro-o-iodotoluene
• o-Iodo-alpha,alpha,alpha-trifluorotoluene
• 2-Iodobenzotrifluoride,99%
• 1-iodo-2-(trifluoromethyl)-benzen
• 2-IODO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE
• O-IODINE TRIFLUORO TOLUENE

2-Iodobenzotrifluoride (stabilized with Copper chip)

CAS: 444-29-1

Fórmula: C₇H₄F₃I

Pureza: >98.0%(GC)

Forma y color: Colorless to Light orange to Yellow clear liquid

Peso molecular: 272.01

Ref: 3B-I0383

2-Iodobenzotrifluoride, 99%

CAS: 444-29-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₇H₄F₃I

Pureza: 99%

Forma y color: Liquid, Clear colorless to yellow or pale green

Peso molecular: 272.01

Ref: 02-A15698

2-Iodobenzotrifluoride

CAS: 444-29-1

Fórmula: C₇H₄F₃I

Pureza: 98%

Forma y color: Liquid

Peso molecular: 272.0063

Ref: IN-DA0039E1

2-Iodobenzotrifluoride

CAS: 444-29-1

2-Iodobenzotrifluoride

Fórmula: C₇H₄F₃I

Pureza: 98%

Forma y color: colourless to light yellow liquid

Peso molecular: 272.01g/mol

Ref: 54-PC4890

2-Iodobenzotrifluoride

CAS: 444-29-1

2-Iodobenzotrifluoride is a chemical compound that inhibits protein synthesis by binding to the aryl boronic acid groups of proteins. This compound also has anti-inflammatory properties and can be used as a control agent for inflammatory diseases. 2-Iodobenzotrifluoride is soluble in hydrocarbon solvents and reacts with sodium ions to produce sodium-dependent glucose, which can be used as an energy source for cells. The trifluoromethyl group of 2-iodobenzotrifluoride binds to the amino acids serine and histidine, inhibiting their activity. It also inhibits other enzymes such as cholesteryl ester transfer protein and carbonic anhydrase, which are involved in the production of cholesterol.
2-Iodobenzotrifluoride is also able to inhibit nucleophilic groups such as cysteine thiols (SH) and glut

Fórmula: C₇H₄F₃I

Pureza: Min. 95%

Forma y color: Clear Liquid

Peso molecular: 272.01 g/mol

Ref: 3D-FI37781

2-Iodobenzotrifluoride

CAS: 444-29-1

Fórmula: C₇H₄F₃I

Pureza: 98%

Forma y color: Liquid

Peso molecular: 272.009

Ref: 10-F001194

2-Iodobenzotrifluoride

Producto controlado

CAS: 444-29-1

Applications 2-Iodobenzotrifluoride acts as a reagent in the preparation, cyclooxygenase-1 inhibitory activity, and docking studies of aminoalkoxyphenylbenzamides. Prepartion and SAR of tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors.
References Fukai, R., et al.: ChemMedChem, 6, 550 (2011); Muthukaman, N., et al.: Bioorg. Med. Chem. Lett., 27, 2594 (2017)

Fórmula: C₇H₄F₃I

Forma y color: Neat

Peso molecular: 272.01

Ref: TR-I685630