CAS 446-86-6

Azatioprina

Descripción:

Azatioprina es un medicamento inmunosupresor que se utiliza principalmente para prevenir el rechazo de órganos en pacientes trasplantados y para tratar enfermedades autoinmunitarias como la artritis reumatoide y la enfermedad de Crohn. Su fórmula química es C7H10N4OS, y presenta un anillo de tiazol, que es integral para su mecanismo de acción. Azatioprina es un profármaco que se metaboliza en 6-mercaptopurina, que interfiere con la síntesis de ácidos nucleicos, inhibiendo así la proliferación de linfocitos. Esta acción ayuda a suprimir la respuesta inmune. La sustancia se administra típicamente por vía oral y es conocida por sus posibles efectos secundarios, que incluyen supresión de la médula ósea, trastornos gastrointestinales y mayor susceptibilidad a infecciones. Debido a sus propiedades inmunosupresoras, es esencial un monitoreo cuidadoso de los recuentos sanguíneos durante el tratamiento. Azatioprina se clasifica como una sustancia peligrosa, y se deben tomar las precauciones adecuadas al manejarla en un laboratorio o entorno clínico. Su uso requiere un entendimiento profundo de la historia médica del paciente y de las posibles interacciones medicamentosas.

Fórmula: C₉H₇N₇O₂S

InChI: InChI=1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)

Clave InChI: InChIKey=LMEKQMALGUDUQG-UHFFFAOYSA-N

SMILES: S(C1=C2C(N=CN2)=NC=N1)C3=C(N(=O)=O)N=CN3C

Sinónimos:

• 1H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-
• 6-((1-Methyl-4-Nitroimidazol-5-Yl)Thio)Purine
• 6-(1-Methyl-4-Nitroimidazol-5-Ylthio)Purine
• 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
• 6-(1-Methyl-4-nitromidazol-5-ylthio)purine
• 6-(Methyl-P-Nitro-5-Imidazolyl)-Thiopurine
• 6-[(1-Methyl-4-Nitro-1H-Imidazol-5-Yl)Thio]-1H-Purine
• 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
• 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-5H-purine
• 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
• 9H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-
• Azafor
• Azamune
• Azanin
• Azasan
• Azathioprin
• Azathioprine
• Azathioprine Crystalline
• Azathiopurine
• Azathropine
• Azatioprina
• Azoran
• Azothioprine
• Bw 57-322
• Imuran
• Imurek
• Imurel
• Muran
• Nsc 39084

Azathioprine

CAS: 446-86-6

Azathioprine is an immunosuppressive purine antimetabolite. The mechanism of action of azathioprine is as a nucleic acid synthesis inhibitor. It has shown promise in treatment of alopecia areata (autoimmune hair loss), with no difference in effectiveness between genders. This Thermo Scientific Chemi

Fórmula: C₉H₇N₇O₂S

Peso molecular: 277.26

Ref: 02-J62314

AZATHIOPRINE CRS

CAS: 446-86-6

AZATHIOPRINE CRS

Fórmula: C₉H₇N₇O₂S

Forma y color: Added

Peso molecular: 277.2626

Ref: 41-A1500000

AZATHIOPRINE RS

CAS: 446-86-6

AZATHIOPRINE RS

Fórmula: C₉H₇N₇O₂S

Forma y color: Added

Peso molecular: 277.2626

Ref: 41-ICRS0216

Azathioprine

CAS: 446-86-6

Azathioprine

Fórmula: C₉H₇N₇O₂S

Pureza: 99.5%

Forma y color: Light Yellow

Peso molecular: 277.03819

Ref: 47-26

Azathioprine

CAS: 446-86-6

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Fórmula: C₉H₇N₇O₂S

Forma y color: Light Yellow Powder Clumpy

Peso molecular: 277.03819

Ref: 45-1046001

Azathioprine

CAS: 446-86-6

Fórmula: C₉H₇N₇O₂S

Pureza: 98%

Forma y color: Solid

Peso molecular: 277.2626

Ref: IN-DA003NXT

Azathioprine

CAS: 446-86-6

Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.

Fórmula: C₉H₇N₇O₂S

Pureza: 99.89% - >99.99%

Forma y color: Pale Yellow Crystals From 50% Aq Acetone For The Treatment Of Rheumatoid Arthritis A Known Carcinogen

Peso molecular: 277.26

Ref: TM-T1237

Azathioprine

CAS: 446-86-6

Fórmula: C₉H₇N₇O₂S

Pureza: ≥ 98.0% (dried basis)

Forma y color: Pale yellow to yellow-green powder

Peso molecular: 277.26

Ref: 7W-GP1145

Azathioprine

CAS: 446-86-6

Azathioprine

Pureza: ≥98%

Peso molecular: 277.26g/mol

Ref: 54-BUP18464

Azathioprine

CAS: 446-86-6

Fórmula: C₉H₇N₇O₂S

Peso molecular: 277.26

Ref: 4Z-A-154006

Azathioprine

Producto controlado

CAS: 446-86-6

Fórmula: C₉H₇N₇O₂S

Forma y color: Neat

Peso molecular: 277.26

Ref: 86-MM1532.00

Azathioprine

Producto controlado

CAS: 446-86-6

Fórmula: C₉H₇N₇O₂S

Forma y color: Neat

Peso molecular: 277.26

Ref: 04-C10341000

Azathioprine-13C2-15N

CAS: 446-86-6

Fórmula: C₇₁₃C₂H₇N₆₁₅NO₂S

Peso molecular: 280.24

Ref: 4Z-A-154007

Azathioprine RS

CAS: 446-86-6

Forma y color: Light Yellow

Ref: 2K-1001000021

Azathioprine-d3

Producto controlado

CAS: 446-86-6

Applications Azathioprine-d3, is the labeled analogue of Azathioprine (A803350), an immunosuppressive antimetabolite, also active as disease modifying antirheumatic drug (DMARD).
References Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979), Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979), Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987), Sandborn, W.J., et al.: : Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998,)

Fórmula: C₉H₄D₃N₇O₂S

Forma y color: Neat

Peso molecular: 280.28

Ref: TR-A803353

Azathioprine

Producto controlado

CAS: 446-86-6

Fórmula: C₉H₇N₇O₂S

Forma y color: Neat

Peso molecular: 277.26

Ref: TR-A803350

6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine

CAS: 446-86-6

Pureza: 95.0%

Forma y color: Solid

Peso molecular: 277.260009765625

Ref: 10-F448203

Azathioprine - Bio-X ™

CAS: 446-86-6

Azathioprine belongs to the group of immunosuppressant drugs that suppress the immune system by inhibiting the production of white blood cells (leukocytes). It is used to treat inflammatory diseases, such as rheumatoid arthritis, lupus, and Crohn's disease. Azathioprine is metabolized in the liver. Additionally, this drug inhibits DNA synthesis by binding to nuclear DNA, preventing RNA transcription and protein synthesis in susceptible cells.

Fórmula: C₉H₇N₇O₂S

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 277.26 g/mol

Ref: 3D-BA166065

Azathioprine

CAS: 446-86-6

Immunosuppressant

Fórmula: C₉H₇N₇O₂S

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 277.26 g/mol

Ref: 3D-FA18064

Azathioprine

CAS: 446-86-6

Fórmula: C₉H₇N₇O₂S

Pureza: >98.0%(T)(HPLC)

Forma y color: Light yellow to Yellow to Green powder to crystal

Peso molecular: 277.26

Ref: 3B-A2069