CAS 4465-65-0

(1R,4aS,12aS)-3-[amino(hidroxi)metilideno]-4a,6,7-trihidroxi-N,N,11-trimetil-2,4,5-trioxo-1,2,3,4,4a,5,12,12a-octahidrotetracen-1-amonio

Descripción:

La sustancia química con el nombre "(1R,4aS,12aS)-3-[amino(hidroxi)metilideno]-4a,6,7-trihidroxi-N,N,11-trimetil-2,4,5-trioxo-1,2,3,4,4a,5,12,12a-octahidrotetracen-1-amonio" y el número CAS 4465-65-0 es un compuesto orgánico complejo caracterizado por su intrincada estructura policíclica y múltiples grupos funcionales. Presenta un marco tetracíclico con varios grupos hidroxilo (-OH) y amino (-NH2), lo que contribuye a su posible solubilidad en disolventes polares y actividad biológica. La presencia de grupos trioxo indica un alto grado de oxidación, lo que puede influir en su reactividad y estabilidad. La estereoquímica específica, denotada por las configuraciones R y S, sugiere que el compuesto puede exhibir propiedades quirales, lo que podría afectar sus interacciones en sistemas biológicos. Este compuesto puede ser de interés en la química medicinal debido a su complejidad estructural y la presencia de grupos funcionales que podrían participar en diversas interacciones bioquímicas. Sin embargo, serían necesarios estudios detallados para comprender completamente sus propiedades, reactividad y posibles aplicaciones.

Fórmula: C₂₂H₂₃N₂O₇

InChI: InChI=1/C22H22N2O7/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28/h4-6,11,16,25-26,30-31H,7,23H2,1-3H3/p+1/t11-,16+,22-/m0/s1

4-EPIANHYDROTETRACYCLINE HYDROCHLORIDE CRS

CAS: 4465-65-0

4-EPIANHYDROTETRACYCLINE HYDROCHLORIDE CRS

Fórmula: C₂₂H₂₃ClN₂O₇

Forma y color: Orange. Powder.

Peso molecular: 462.8802

Ref: 41-E0400000

4-Epianhydrotetracycline Hydrochloride

CAS: 4465-65-0

Tetracyclines and their derivatives; salts thereof

Fórmula: C₂₂H₂₂N₂O₇·HCl

Forma y color: Dark Yellow Brown Solid

Peso molecular: 426.1427

Ref: 45-1236506

4-Epianhydrotetracycline hydrochloride

CAS: 4465-65-0

EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.

Fórmula: C₂₂H₂₃ClN₂O₇

Forma y color: Solid

Peso molecular: 462.88

Ref: TM-T36599

4-Epianhydrotetracycline hydrochloride

Producto controlado

CAS: 4465-65-0

Fórmula: C₂₂H₂₂N₂O₇·ClH

Forma y color: Neat

Peso molecular: 462.88

Ref: 04-C13174500

Tetracycline EP Impurity D HCl (Chlortetracycline EP Impurity I HCl , Lymecycline EP Impurity D HCl , 4-Epianhydrotetracycline HCl )

CAS: 4465-65-0

Fórmula: C₂₂H₂₂N₂O₇·HCl

Peso molecular: 426.43 36.46

Ref: 4Z-T-4035

4-Epianhydrotetracycline Hydrochloride Hydrate (>85%)

Producto controlado

CAS: 4465-65-0

Applications An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study. This compound is a contaminant of emerging concern (CECs).
References Simmons, D., et al.: J. Pharm. Sci., 55, 1313 (1966), Paemen, L., et al.: Biochem. Pharmacol., 52, 105 (1996),

Fórmula: C₂₂H₂₂N₂O₇·HCl·H₂O

Pureza: >85%

Forma y color: Neat

Peso molecular: 462.88

Ref: TR-E578070

4-Epianhydrotetracycline hydrochloride

CAS: 4465-65-0

4-Epianhydrotetracycline hydrochloride is a chemically modified antibiotic derivative, originating from the structural transformation of tetracycline. It is derived through epimerization and dehydration processes, which alter the parent compound's structure.

Fórmula: C₂₂H₂₃ClN₂O₇

Pureza: Min. 95%

Peso molecular: 462.9 g/mol

Ref: 3D-EAA46565

Tetracycline EP Impurity D

CAS: 4465-65-0

Fórmula: C₂₂H₂₂N₂O₇HCl

Peso molecular: 426.4 : 36.46

Ref: ST-EA-CP-T200006

4-Epianhydrotetracycline hydrochloride hydrate

CAS: 4465-65-0, 7518-17-4

4-Epianhydrotetracycline hydrochloride hydrate is a chemical compound that inhibits the activation of protein kinase C (PKC) and blocks the apoptosis pathway. It has been shown to induce apoptosis in prostate cancer cells and also inhibits the proliferation of human microvessel endothelial cells. 4-Epianhydrotetracycline hydrochloride hydrate is stable in both human serum and wastewater, which makes it an ideal drug for treating many types of cancers. It is also used in pharmaceutical drugs as a cytochalasin, which are used to treat angina pectoris by reducing oxygen uptake by erythrocytes, thereby inhibiting oxidative phosphorylation. 4-Epianhydrotetracycline hydrochloride hydrate prevents mitochondrial cytochrome c release, thus blocking the apoptotic pathway in cells. This chemical compound may act as a regulatory molecule that affects energy metabolism and epidermal growth factor (EGF)

Fórmula: C₂₂H₂₃ClN₂O₇

Pureza: Min. 95%

Peso molecular: 462.88 g/mol

Ref: 3D-FE22716