CAS 470-40-6

Tujopseno

Descripción:

Tujopseno es un compuesto orgánico natural clasificado como un sesquiterpeno, derivado principalmente de los aceites esenciales de ciertos árboles coníferos, particularmente aquellos de la familia Cupressaceae. Se caracteriza por su compleja estructura bicíclica, que contribuye a sus propiedades físicas y químicas únicas. Tujopseno es típicamente un líquido incoloro a amarillo pálido con un aroma característico a madera y tierra, lo que lo hace valioso en las industrias de fragancias y sabores. Su fórmula molecular es C15H24, y tiene un punto de ebullición relativamente bajo, lo que permite que se vaporice fácilmente. Tujopseno exhibe propiedades hidrofóbicas, lo que lo hace insoluble en agua pero soluble en disolventes orgánicos. Además, se ha estudiado por sus posibles actividades biológicas, incluidos efectos antimicrobianos y antiinflamatorios, aunque se necesita más investigación para comprender completamente su potencial farmacológico. Debido a su origen natural y perfil de aroma único, Tujopseno se utiliza a menudo en perfumería y como agente saborizante natural.

Fórmula: C₁₅H₂₄

InChI: InChI=1/C15H24/c1-11-6-9-14(4)8-5-7-13(2,3)15(14)10-12(11)15/h6,12H,5,7-10H2,1-4H3/t12-,14-,15-/m0/s1

Clave InChI: InChIKey=WXQGPFZDVCRBME-QEJZJMRPSA-N

SMILES: C[C@@]12[C@@]3([C@@](C3)(C(C)=CC1)[H])C(C)(C)CCC2

Sinónimos:

• (1AS-(1aalpha,4abeta,8aR*))-1,1a,4,4a,5,6,7,8-octahydro-2,4a,8,8-tetramethylcyclopropa(d)naphthalene
• (1aS,4aS,8aS)-1,1a,4,4a,5,6,7,8-Octahydro-2,4a,8,8-tetramethylcyclopropa[d]naphthalene
• (1aS,4aS,8aS)-2,4a,8,8-tetramethyl-1,1a,4,4a,5,6,7,8-octahydrocyclopropa[d]naphthalene
• Cyclopropa(d)naphthalene, 1,1a,4,4a,5,6,7,8-octahydro-2,4a,8,8-tetramethyl-, (1aS,4aS,8aS)-
• Cyclopropa[d]naphthalene, 1,1a,4,4a,5,6,7,8-octahydro-2,4a,8,8-tetramethyl-, [1aS-(1aα,4aβ,8aR*)]-
• Nsc 44707
• Sesquichamene
• Thujopsen
• Thujopsene
• Widdrene
• cis-(-)-Thujopsene
• (1S,6S,10S)-2,2,6,9-TETRAMETHYL-TRICYCLO[8.1.0.0(1.6)]UNDEC-8-ENE
• cyclopropa[d]naphthalene,
• [1aS,4aS,8aS,(-)]-1,1a,4,4a,5,6,7,8-Octahydro-2,4aβ,8,8-tetramethylcyclopropa[d]naphthalene
• (1aS,8aS)-1,1aα,4,4a,5,6,7,8-Octahydro-2,4aβ,8,8-tetramethylcyclopropa[d]naphthalene
• 4abeta,8atheta)]-as-(1aalph
• (-)-Thujopsene >=97.0% (GC)
• (Z)-Thujopsene
• THUJOPSEN, (-)-(SG)(CALL)
• (1S,6S,10S)-2,2,6,9-Tetramethyl-1,10-methanobicyclo[4.4.0]deca-8-ene
• Einecs 207-426-8
• THUJOPSEN, (-)-(SG)
• 2,4a,8,8-Tetramethyl-1,1a,4,4a,5,6,7,8-octahydrocyclopropa[d]naphthalene
• Cyclopropa[d]naphthalene, 1,1a,4,4a,5,6,7,8-octahydro-2,4a,8,8-tetramethyl-, [1aS-(1aalpha,4abeta,8aR*)]-

(-)-Thujopsene

CAS: 470-40-6

Fórmula: C₁₅H₂₄

Forma y color: Clear, colourless liquid

Peso molecular: 204.35

Ref: 7W-GL4199

Thujopsene

CAS: 470-40-6

Thujopsene, a sesquiterpene found in T. dolabrata, exhibits a wide range of biological activities. It inhibits Na+/K+-ATPase and cytochrome P450 (CYP) isoform CYP2B6 with IC50 values of 25.9 µg/ml and Ki of 0.8 µM, respectively. Additionally, thujopsene demonstrates antimicrobial efficacy against both Gram-positive and Gram-negative bacteria, such as S. aureus, M. luteus, and S. typhimurium, with MICs ranging from 25-50 µg/ml. It also suppresses antigen-induced β-hexosaminidase release in IgE-sensitized RBL-2H3 mast cells (IC50= 25.1 µM) and shows cytotoxicity against A549 non-small cell lung cancer cells with an LC50 of 35.27 µg/ml. Furthermore, thujopsene causes mortality in mites D. farinae and T. putrescentiae, with LC50s of 9.82 and 10.92 µg/cm2, respectively.

Fórmula: C₁₅H₂₄

Forma y color: Solid

Peso molecular: 204.35

Ref: TM-TN7505

(-)-Thujopsene (>85%)

Producto controlado

CAS: 470-40-6

Fórmula: C₁₅H₂₄

Pureza: >85%

Forma y color: Colourless

Peso molecular: 204.35

Ref: TR-T910060

(-)-Thujopsene

CAS: 470-40-6

Thujopsene is a natural compound found in plants, such as Astragalus species. It has been shown to have antimicrobial properties against bacteria. Thujopsene is an alkanoic acid with a chemical formula of CH3(CH2)2OCH2CH=CH(CH3)CO2H. This compound is soluble in organic solvents and can be extracted from plants with methyl myristate or ether. Thujopsene also has been shown to have effects on the activity of enzymes, such as lipase and phospholipase, which may be due to its fatty acid chains. Thujopsene has been used as a starting point for the synthesis of other compounds for use in drug development and analysis techniques, such as gas chromatography-mass spectrometry (GC-MS).

Fórmula: C₁₅H₂₄

Pureza: Min. 85 Area-%

Forma y color: Clear Liquid

Peso molecular: 204.35 g/mol

Ref: 3D-FT171510