CAS 475-25-2

Hematina

Descripción:

Hematina, con el número CAS 475-25-2, es un compuesto químico derivado de la hematoxilina, un tinte natural extraído del tronco del árbol Haematoxylum campechianum. Es conocido principalmente por su uso como un tinte histológico en laboratorios biológicos y médicos, particularmente para teñir núcleos celulares en secciones de tejido. Hematina exhibe un color azul profundo a púrpura cuando se oxida, lo que mejora la visibilidad de las estructuras celulares bajo un microscopio. El compuesto es soluble en alcohol y agua, lo que lo hace versátil para varios protocolos de tinción. Hematina funciona al unirse a ácidos nucleicos, permitiendo la diferenciación de componentes celulares durante el examen microscópico. Además, es importante manejar Hematina con cuidado, ya que puede ser un irritante potencial. Sus aplicaciones se extienden más allá de la histología e incluyen su uso en varios campos como la bioquímica y la biología molecular, donde ayuda en la visualización de la morfología y patología celular. En general, Hematina es una herramienta valiosa en la investigación científica y el diagnóstico.

Fórmula: C₁₆H₁₂O₆

InChI: InChI=1S/C16H12O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,17,19-21H,5-6H2

Clave InChI: InChIKey=HLUCICHZHWJHLL-UHFFFAOYSA-N

SMILES: OC12C(=C3C(C1)=CC(=O)C(O)=C3)C=4C(OC2)=C(O)C(O)=CC4

Sinónimos:

• (6aR)-3,4,6a-trihydroxy-6a,11-dihydroindeno[2,1-c]chromene-9,10(6H,7H)-dione
• (6aS)-3,4,6a,10-tetrahydroxy-6a,7-dihydroindeno[2,1-c]chromen-9(6H)-one
• (6aS)-3,4,6a-trihydroxy-6a,11-dihydroindeno[2,1-c]chromene-9,10(6H,7H)-dione
• 3,4,6a,10-Tetrahydroxy-6a,7-dihydrobenz(b)indeno(1,2-d)pyran-9(6H)-one
• 3,4,6a,10-tetrahydroxy-6a,7-dihydroindeno[2,1-c]chromen-9(6H)-one
• Ai3-63013
• Benz(b)indeno(1,2-d)pyran-9(6H)-one, 6a,7-dihydro-3,4,6a,10-tetrahydroxy-
• Brn 0093039
• Haematein
• Hematein
• Hematine
• Nsc 7333
• Unii-88Q1Syd10B

Hematein

CAS: 475-25-2

Fórmula: C₁₆H₁₂O₆

Forma y color: Solid

Peso molecular: 300.2629

Ref: IN-DA00DDWV

Hematein

CAS: 475-25-2

Hematein blocks Akt/PKB, Wnt signaling, promotes apoptosis in lung cancer, is a dye from hematoxylin, and inhibits casein kinase II (IC50: 0.74 μM).

Fórmula: C₁₆H₁₂O₆

Pureza: 98%

Forma y color: Dark Brown Crystalline Powder

Peso molecular: 300.26

Ref: TM-T15469

Hematein

CAS: 475-25-2

Hematein

Pureza: ≥95%

Peso molecular: 300.26g/mol

Ref: 54-BUP17537

Hematein

CAS: 475-25-2

Fórmula: C₁₆H₁₂O₆

Forma y color: Brown to dark brown powder

Peso molecular: 300.26

Ref: 7W-GT7429

Hematein

CAS: 475-25-2

Fórmula: C₁₆H₁₂O₆

Forma y color: Dark Brown Solid

Peso molecular: 300.27

Ref: 4Z-H-050001

Hematein (Technical Grade)

CAS: 475-25-2

Applications Hematein is a stain for the cell nuclei of animal tissue. Also suggested to possess use as a stain for myelin sheaths and nerve fibers. An oxidized version of hematoxylin. Color index: 75290. Dyes and metabolites.

Fórmula: C₁₆H₁₂O₆

Forma y color: Neat

Peso molecular: 300.28

Ref: TR-H245653

Hematein

CAS: 475-25-2

Hematein is an extract of the traditional Chinese herb, Alisma plantago-aquatica. Hematein has been shown to exhibit antioxidant and anti-inflammatory activities in vitro and in vivo. It's mechanism of action appears to be related to its ability to inhibit the activity of several enzymes, including xanthine oxidase, nitric oxide synthase (NOS), cyclooxygenase (COX), lipoxygenases (LOX), 5'-nucleotidase, and protein kinases. Hematein also binds to cell nuclei and inhibits staining with hematoxylin, which may account for its ability to inhibit DNA synthesis. Hematein has been shown to protect cells from oxidative damage induced by hydrogen peroxide in a dose-dependent manner. The protective effects were observed as early as 30 minutes after treatment with hematein and were concentration dependent up to a concentration of 10 μM. In addition, hematein showed significant protection

Fórmula: C₁₆H₁₂O₆

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 300.26 g/mol

Ref: 3D-FH59506