CAS 481-42-5

Plumbagina

Descripción:

Plumbagina, con el número CAS 481-42-5, es un compuesto de naftoquinona que se encuentra de forma natural, derivado principalmente de las raíces de la planta *Plumbago*, en particular de *Plumbago zeylanica*. Se caracteriza por su apariencia cristalina de color amarillo a naranja y tiene una fórmula molecular de C11H8O3. Plumbagina exhibe una variedad de actividades biológicas, incluyendo propiedades antimicrobianas, anticancerígenas y antioxidantes, lo que lo hace de interés en la investigación farmacológica. Se sabe que el compuesto interactúa con diversas vías celulares, potencialmente influyendo en la apoptosis y la proliferación celular. Además, se ha estudiado Plumbagina por su capacidad para inhibir ciertas enzimas y su papel en la medicina tradicional. Su solubilidad es generalmente mayor en disolventes orgánicos que en agua, lo cual es una característica común de muchos compuestos orgánicos. Sin embargo, debido a su naturaleza reactiva, Plumbagina puede sufrir oxidación y otras transformaciones químicas, lo que puede afectar su estabilidad y eficacia en diversas aplicaciones. En general, Plumbagina representa un compuesto significativo tanto en la química de productos naturales como en la investigación medicinal.

Fórmula: C₁₁H₈O₃

InChI: InChI=1/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3

Clave InChI: InChIKey=VCMMXZQDRFWYSE-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)C=C1C)=C(O)C=CC2

Sinónimos:

• 1,4-Naphthalenedione, 5-hydroxy-2-methyl-
• 1,4-Naphthoquinone, 5-hydroxy-2-methyl-
• 2-Methyl-5-hydroxy-1,4-naphthalenedione
• 2-Methyl-5-hydroxy-1,4-naphthoquinone
• 2-Methyljuglone
• 5-Hydroxy-2-Methylnaphthalene-1,4-Dione
• 5-Hydroxy-2-methyl-1,4-naphthalenedione
• 5-Hydroxy-2-methyl-1,4-naphthoquinone
• NSC 236613
• NSC 688284
• Plumbagin from Plumbago indica
• Plumbagin,95%
• Plumbagine
• Plumbagone
• Plumbagin
• Plumbagin, 99+%
• Ophioxylin
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene, 5-Hydroxy-2-methyl-1,4-naphthoquinone, Plumbagin
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene, 5-Hydroxy-2-methyl-1,4-naphthoquinone
• PLUMBAGIN(RG)
• PLUMBAGIN PRACTICAL GRADE
• SPECS AP-782/41885488
• RARECHEM BW GA 0426
• 5-hydroxy-2-methyl-4-naphthoquinone
• plumbapin
• 5-HYDROXY-2-METHYL-1,4-NAPTHOQUINONE
• Plumbagin (natural)
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene
• PLANT STEROLS KIT
• 5-hydroxy-2-methyl-4-naphthalenedione
• PLUMBAGIN FROM FROM PLUMBAGO INDICA
• PLUMBAGAN

Plumbagin

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Pureza: >98.0%(T)(HPLC)

Forma y color: Orange to Brown powder to crystal

Peso molecular: 188.18

Ref: 3B-P1139

Plumbagin

CAS: 481-42-5

Plumbagin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₁H₈O₃

Pureza: (HPLC) ≥90%

Forma y color: Powder

Peso molecular: 188.18

Ref: 11-0444

5-Hydroxy-2-methylnaphthalene-1,4-dione

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 188.1794

Ref: IN-DA003TTF

Plumbagin

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Peso molecular: 188.18

Ref: 7W-GL1138

Plumbagin

CAS: 481-42-5

Plumbagin

Pureza: ≥98%

Peso molecular: 188.18g/mol

Ref: 54-BUP11118

plumbapin

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Pureza: 95%~99%

Peso molecular: 188.182

Ref: BP-BP1113

5-Hydroxy-2-methylnaphthalene-1,4-dione

CAS: 481-42-5

5-Hydroxy-2-methylnaphthalene-1,4-dione

Fórmula: C₁₁H₈O₃

Pureza: 95%

Forma y color: reddish orange/tan powder

Peso molecular: 188.18g/mol

Ref: 54-OR1174

Plumbagin

CAS: 481-42-5

Plumbagin, a yellow dye from naphthoquinone, is isolated from Plumbago and found in Drosera, Nepenthes, and black walnut drupe.

Fórmula: C₁₁H₈O₃

Pureza: 99.7% - 99.95%

Forma y color: Soild

Peso molecular: 188.18

Ref: TM-T2841

Plumbagin

CAS: 481-42-5

Plumbagin

Fórmula: C₁₁H₈O₃

Pureza: By hplc: 99.4% by area (210nm) (Typical Value in Batch COA)

Forma y color: reddish orange/tan powder

Peso molecular: 188.18g/mol

Ref: 54-BIDF1037

Plumbagin

CAS: 481-42-5

Quinone

Fórmula: C₁₁H₈O₃

Pureza: ≥ 98.0 % (HPLC)

Forma y color: Powder

Peso molecular: 188.18

Ref: 5G-80267

Plumbagin

CAS: 481-42-5

Applications Plumbagin induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

Fórmula: C₁₁H₈O₃

Forma y color: Dark Orange

Peso molecular: 188.18

Ref: TR-P627000

Plumbagin

CAS: 481-42-5

Plumbagin is a quinonoid compound, which is a secondary metabolite found in the roots of Plumbago species. This compound is characterized by its naphthoquinone structure, which is responsible for its diverse biological activities. Plumbagin exerts its effects primarily through the generation of reactive oxygen species (ROS), modulation of cellular signaling pathways, and inhibition of specific enzyme functions, such as topoisomerases. These actions result in the modulation of cell proliferation, apoptosis, and inflammation, making Plumbagin a compound of interest for various biomedical applications.

Fórmula: C₁₁H₈O₃

Pureza: Min. 95%

Forma y color: Orange Powder

Peso molecular: 188.18 g/mol

Ref: 3D-FP13778

5-Hydroxy-2-methyl-[1,4]naphthoquinone

CAS: 481-42-5

Fórmula: C₁₁H₈O₃

Pureza: 98%

Forma y color: No data available.

Peso molecular: 188.182

Ref: 10-F032384

Plumbagin-d3

Producto controlado

CAS: 481-42-5

Applications Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

Fórmula: C₁₁H₅D₃O₃

Forma y color: Neat

Peso molecular: 191.2

Ref: TR-P627002