CAS 4836-13-9

N4-benzoil-2'-desoxicitidina

Descripción:

N4-benzoil-2'-desoxicitidina, con el número CAS 4836-13-9, es un nucleósido modificado que presenta un grupo bencilo unido al átomo de nitrógeno en la posición 4 de la base de citidina. Este compuesto se caracteriza por sus componentes estructurales, que incluyen un azúcar de desoxirribosa y una base de pirimidina, específicamente citidina. La modificación bencilo mejora su lipofilia y puede influir en su actividad biológica, lo que lo hace de interés en la química medicinal y la biología molecular. N4-benzoil-2'-desoxicitidina se estudia a menudo por sus posibles aplicaciones en terapias antivirales y anticancerígenas, ya que las modificaciones a los nucleósidos pueden afectar su interacción con ácidos nucleicos y enzimas. Además, este compuesto puede exhibir propiedades únicas de solubilidad y estabilidad en comparación con los nucleósidos no modificados, lo que puede ser ventajoso en la formulación y entrega de medicamentos. Su síntesis generalmente implica la acilación de 2′-desoxi-citidina, y se puede analizar utilizando diversas técnicas espectroscópicas para confirmar su estructura y pureza.

Fórmula: C₁₆H₁₇N₃O₅

InChI: InChI=1/C16H17N3O5/c20-9-12-11(21)8-14(24-12)19-7-6-13(18-16(19)23)17-15(22)10-4-2-1-3-5-10/h1-7,11-12,14,20-21H,8-9H2,(H,17,18,22,23)/t11-,12+,14+/m1/s1

Clave InChI: InChIKey=MPSJHJFNKMUKCN-OUCADQQQSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=CC(NC(=O)C3=CC=CC=C3)=N1

Sinónimos:

• 4-(benzoylamino)-1-(2-deoxy-beta-L-erythro-pentofuranosyl)pyrimidin-2(1H)-one
• 4-N-Benzoyldeoxycytidine
• Benzamide, N-[1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-
• Cytidine, N-benzoyl-2′-deoxy-
• N-Benzoyl-2′-deoxycytidine
• N-Benzoyldeoxycytidine
• N4-Benzoyl-2'-deoxycytidine
• N⁴-Benzoyl-2′-deoxycytidine
• N⁴-Benzoyldeoxycytidine
• Benzamide, N-[1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-
• N4-Benzoyldeoxycytidine
• N-Benzoyl-2-Deoxy-Cytidine
• Bz-dC
• DC-N-BZ
• n-benzoyl-2’-deoxy-cytidin
• N(sup 4)benzoyl-2'-deoxycytidine
• NBZ-2'-DC
• N-BZ-DC
• N-[1-(2-Deoxy-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide
• N4-BZ-2'-DEOXYCYTIDINE
• DC-BZ 99.0%
• 4-(Benzoylamino)-1-(2-deoxy-beta-L-erythro-pentofuranosyl)-2(1H)-pyrimidinone
• DC-BZ/N-BENZOYL-2''-DEOXY-CYTIDIN
• DC-BZ

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Fórmula: C₁₆H₁₇N₃O₅

Pureza: >98.0%(HPLC)(N)

Forma y color: White to Almost white powder to crystal

Peso molecular: 331.33

Ref: 3B-B3102

N-Benzoyl-2'-deoxycytidine, 98+%

CAS: 4836-13-9

N-Benzoyl-2'-deoxycytidine, 98+%

Fórmula: C₁₆H₁₇N₃O₅

Pureza: 98+%

Peso molecular: 331.33

Ref: 02-H52298

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Fórmula: C₁₆H₁₇N₃O₅

Pureza: 97%

Forma y color: Solid

Peso molecular: 331.3233

Ref: IN-DA006WUB

N-Benzoyl-2-Deoxy-Cytidine

CAS: 4836-13-9

N-Benzoyl-2-Deoxy-Cytidine

Pureza: 98%

Peso molecular: 331.32g/mol

Ref: 54-OR1014255

N4-Benzoyl-2′-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2′-deoxycytidine

Pureza: ≥98%

Peso molecular: 331.32g/mol

Ref: 54-BUP16481

N4-Benzoyl-2''-deoxycytidine

CAS: 4836-13-9

Fórmula: C₁₆H₁₇N₃O₅

Peso molecular: 331.33

Ref: 7W-GN9700

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Pureza: 98.0%

Forma y color: Solid, No data available.

Peso molecular: 331.3280029296875

Ref: 10-F434668

N4-Benzoyl-2′-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase.

Fórmula: C₁₆H₁₇N₃O₅

Pureza: 99.41%

Forma y color: Solid

Peso molecular: 331.32

Ref: TM-T7961

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.

Fórmula: C₁₆H₁₇N₃O₅

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 331.33 g/mol

Ref: 3D-NB02991

N4-Benzoyl-2'-deoxy-a-cytidine

CAS: 4836-13-9

N4-Benzoyl-2'-deoxy-a-cytidine is a novel, modified nucleoside that has shown anticancer and antiviral activity. It is synthesized by the enzymatic oxidation of 2'-deoxyadenosine with benzoyl chloride and sodium bicarbonate. N4-Benzoyl-2'-deoxy-a-cytidine has been shown to activate transcription, increase DNA synthesis, and inhibit virus replication. It also inhibits bacterial growth, but does not appear to have any effect on mammalian cells.

Fórmula: C₁₆H₁₇N₃O₅

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 331.32 g/mol

Ref: 3D-NB08374

N-Benzoyldeoxycytidine

Producto controlado

CAS: 4836-13-9

Applications N-Benzoyldeoxycytidine is proetected Deoxycytidine (2’-deoxy, D232615) which is a Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity.
References Hecht, S., et al.: Chem. Res. Toxicol., 17, 588 (2004), Choi, J., et al.: J. Biol. Chem., 281, 38244 (2006), Lao, Y., et al.: Chem. Res. Toxicol., 20, 246 (2007)

Fórmula: C₁₆H₁₇N₃O₅

Forma y color: Neat

Peso molecular: 331.32

Ref: TR-B208000