CAS 484598-36-9

ProTx II

CAS: 484598-36-9

Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.

Fórmula: C₁₆₈H₂₅₀N₄₆O₄₁S₈

Pureza: 98%

Forma y color: Solid

Peso molecular: 3826.59

Ref: TM-TP1680

ProTx-II

CAS: 484598-36-9

ProTx-II is a synthetic peptide that activates the TRPV1 receptor, a member of the capsaicin receptor family. ProTx-II has been shown to inhibit NGF-induced neurite outgrowth, and can be used as a research tool in studying the structure and function of TRPV1 receptors. ProTx-II is also an inhibitor of protein interactions with the TNF receptor, and has been shown to selectively inhibit NFκB activation by inhibiting IKK kinase activity.

Fórmula: C₁₆₈H₂₅₀N₄₆O₄₁S₈

Pureza: Min. 95%

Peso molecular: 3,826.6 g/mol

Ref: 3D-PTX-4450-S

ProTx-II

CAS: 484598-36-9

A spider venom-derived peptide whose sequence is derived from the Tarantula, Thrixopelma pruriens which can be applied as a Na+ Channel (Especially Nav1.7) / Ca2+ Ion Channel Blocker (Gating Modifier). This product has disulfide bonds between Cys2-Cys16, Cys9-Cys21, and Cys15-Cys25 and is available as a trifluoroacetate salt. For a smaller quantity in acetate form, see PTX-4450-S.

Fórmula: C₁₆₈H₂₅₀N₄₆O₄₁S₈

Pureza: Min. 95%

Peso molecular: 3,826.66 g/mol

Ref: 3D-PTX-3995-PI

ProTx II

CAS: 484598-36-9

ProTx II is a synthetic, non-steroidal compound that has been shown to inhibit the Na+ channel and to have an inhibitory effect on amines. ProTx II is being investigated as a treatment for diabetic neuropathy and as a possible chemotherapeutic agent.

Fórmula: C₁₆₈H₂₅₀N₄₆O₄₁S₈

Pureza: Min. 95%

Peso molecular: 3,827 g/mol

Ref: 3D-JUA59836