![[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-benzenebutanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F19813-boc-r-3-amino-4-245-trifluoro-phenyl-butyric-acid.webp&w=3840&q=75)
CAS 486460-00-8
:ácido [(1,1-dimetiletoxicarbonil)amino]-2,4,5-trifluoro-(R)-bencenobutanoico
Descripción:
La sustancia química conocida como "ácido [(1,1-dimetiletoxicarbonil)amino]-2,4,5-trifluoro-(R)-bencenobutanoico," con el número CAS 486460-00-8, es un compuesto orgánico complejo caracterizado por sus grupos funcionales y características estructurales únicas. Contiene un grupo amino, un ácido carboxílico y un grupo trifluorometilo, que contribuyen a su reactividad y posibles aplicaciones en química medicinal. La presencia del grupo 1,1-dimetiletoxicarbonilo sugiere que puede servir como un grupo protector en rutas sintéticas. Los sustituyentes trifluorometilo mejoran la lipofilia y pueden influir en la actividad biológica, lo que hace que este compuesto sea de interés en el diseño de fármacos. Además, la quiralidad indicada por la configuración (R) sugiere que el compuesto puede exhibir propiedades estereoespecíficas, lo que puede ser crucial para su interacción con objetivos biológicos. En general, las características distintivas de este compuesto lo convierten en un tema valioso para la investigación en síntesis orgánica y desarrollo farmacéutico.
Fórmula:C15H18F3NO4
InChI:InChI=1/C15H18F3NO4/c1-15(2,3)23-14(22)19-9(6-13(20)21)4-8-5-11(17)12(18)7-10(8)16/h5,7,9H,4,6H2,1-3H3,(H,19,22)(H,20,21)/t9-/m1/s1
SMILES:CC(C)(C)OC(=N[C@H](Cc1cc(c(cc1F)F)F)CC(=O)O)O
Sinónimos:- Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)-butyric acid
- (3R)-N-(Tert-Butoxycarbonyl)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid
- (3R)-3-(1,1-Dimethylethoxy Carbonyl) Amino]-4-(2,4,5-Trifluorophenyl) Butanoic Acid
- Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid
- (R)-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
- (R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
- (3R)-3-[(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid
- Benzenebutanoic acid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-, (3R)-
- Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid
- (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
- (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid
- (R)-3-(tert-butoxy carbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
- 3(R)-tert-Butoxycarbonylamino-4-(2,4,5-trifluoro-phenyl)-butyric acid
- (R)-3-[(Tert-Butoxycarbonyl)amino]-4-(2,4,5-Trifluoro Phenyl)butanoic Acid
- (Tert-Butoxy)Carbonyl (R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid
- 5-TRIFLUORO-PHENYL)-BUTYRIC ACID
- Sitagliptin interMediate
- (3R)-N-Boc-3-amin
- Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid / Sitagliptin Intermediate
- Parecoxib SodiuM API
- (3R)-3-{[(tert-butoxy)carbonyl]amino}-4-(2,4,5-trifluorophenyl)butanoic acid
- N-Boc Sitagliptin Acid Impurity
- Sitagliptin EP Impurity 15
- (R)-3-(Tert-Butoxycarbonyl)-4-(2,4,5-Trifluorophenyl)Butanoic Acid
- (R)-N-Boc-3-AMino-4-(2,4,5-trifluorophenyl)butanoic 
- Sitagliptin N-BOC Carboxylic Acid
- Sitagliptin Impurity 19
- Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,(bR)-
- (3R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BU
- [[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-be...
- Sitagliptin Intermediate 1
- Sitagliptin interMediateB
- Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
- Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-ButyricAci
- (βR)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-trifluorobenzenebutanoic acid
- [[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-(R)-benzenebuta
- Sitagliptin Acid Boc Impurity (Impurity A)
- BOC-(R-)3-Amino-4(2,4,5-triflurophenyl)Butanoic acid
- BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID ISO 9001：2015 REACH
- (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluoro phenyl)butanoic acid [Sita Acid]
- butanoic acid (BOC acid)
- (R)-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid
- Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (Boc acid)
- (3R)-N-(tert-Butoxycarbonyl)-3-aMino-4-(2,4,5-trifluorophenyl)-butanoic acid- Boc-(R)-3-AMino-4-(2,4,5-trifluorophenyl)
- Benzenebutanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-, (βR)-
- Sitagliptin Impurity 78
- BOC-(R)-3-AMINO-4-(2
- (R)-Sitagliptin N-Boc-Acid IMpurity
- [[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-benzenebutanoic acid
- (3R)-3-((1,1-DIMETHYLETHOXYCARBONYL)AMINO)-4-(2,4,5-TRIFLUROPHENYL)-BUTANOIC ACID
- 4-(6-{[(tert-butoxy)carbonyl]aMino}-1,2,5-trifluorocyclohexa-2,4-dien-1-yl)butanoic acid
- Boc-(R)-3-Amino-4-(2,4,5-trifluorphenyl)butanoic acid
- SITAGLIPTIN CAS 654671-78-0 INTERMEDIATES
- BOC- Butanoic Acid
- Sitagliptin N-BOC Carboxylic acid Impurity
- (3R)-N-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
- Sitagliptin Imp-1(sitagliptin Impurity-A)
- Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid, >=99%
- BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENY
- Sitagliptin Impurity 19 ((R)-Sitagliptin N-Boc-Acid Impurity)
- (R)-3-(Boc-aMino)-4-(2,4,5-trifluorophenyl)butanoic acid
- (3R) - N - (tert butoxycarbonyl) -3-amino-4- (2,4,5-trifluorophenyl) butyric acid
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Encontrado 8 productos.
(3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:Fórmula:C15H18F3NO4Pureza:97%Forma y color:SolidPeso molecular:333.3029Sitagliptin Impurity 19 ((R)-Sitagliptin N-Boc-Acid Impurity)
CAS:Fórmula:C15H18F3NO4Forma y color:White To Off-White SolidPeso molecular:333.31(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acidPureza:98%Peso molecular:333.306g/mol(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
CAS:Producto controlado<p>Applications (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin.<br>References Kim, H.J., et. al.: Bioorg. Med. Chem. Lett., 22, 5545 (2012)<br></p>Fórmula:C15H18F3NO4Forma y color:NeatPeso molecular:333.30(R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:Fórmula:C15H18F3NO4Pureza:95%Forma y color:SolidPeso molecular:333.307Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:<p>Intermediate in the synthesis of sitagliptin</p>Fórmula:C15H18F3NO4Pureza:Min. 95%Peso molecular:333.3 g/mol
![(3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0038OZ.jpg&w=3840&q=75)
![(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FPC99712.jpg&w=3840&q=75)
