CAS 489-32-7
:Icarina
Descripción:
Icarina es un glucósido flavonoide derivado principalmente del género Epimedium, comúnmente conocido como Hierba de Cabra Apasionada. Se reconoce por sus posibles propiedades farmacológicas, incluyendo efectos antioxidantes, antiinflamatorios y neuroprotectores. Icarina exhibe una estructura compleja caracterizada por un esqueleto de flavona con un moiety glucósido, que contribuye a su actividad biológica. La sustancia se estudia a menudo por sus posibles beneficios en la mejora de la salud sexual y el aumento de la densidad ósea, lo que la hace de interés en la medicina tradicional y la investigación terapéutica moderna. Icarina se encuentra típicamente en varias formas, incluyendo polvos y extractos, y se utiliza a menudo en suplementos dietéticos. Su solubilidad en disolventes orgánicos y su solubilidad limitada en agua pueden influir en su biodisponibilidad y eficacia. Al igual que con muchos compuestos naturales, los efectos específicos y los mecanismos de acción de Icarina aún están bajo investigación, y su perfil de seguridad es una consideración importante para su uso en productos de salud.
Fórmula:C33H40O15
InChI:InChI=1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
Clave InChI:InChIKey=TZJALUIVHRYQQB-XLRXWWTNSA-N
SMILES:C(C=C(C)C)C1=C2C(C(=O)C(O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)=C(O2)C4=CC=C(OC)C=C4)=C(O)C=C1O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
Sinónimos:- 2,6-anhydro-1-deoxy-7-O-[7-(beta-D-glucopyranosyloxy)-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-4H-chromen-3-yl]-L-glycero-L-manno-heptitol
- 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
- 3-[(6-Deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)oxy]-7-(β-<smallcap>D</span>-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
- 3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside
- 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)oxy]-7-(β-<smallcap>D</span>-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
- 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)oxy]-7-(β-<smallcap>D</span>-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-
- Epimedium
- Epimedium PE
- Epimedium extract
- Horny goat weed extract
- Icariine
- Icariln
- Ieariline
- Epimediun P.E.
- 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-
- 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
- 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
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Encontrado 16 productos.
Icariin
CAS:Fórmula:C33H40O15Pureza:>96.0%(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:676.67Icariin, 98%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Fórmula:C33H40O15Pureza:98%Forma y color:Pale yellow, PowderPeso molecular:676.67Icariin
CAS:Icariin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C33H40O15Pureza:(HPLC) ≥99%Forma y color:PowderPeso molecular:676.67Icariin
CAS:Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator. Icariin has been reported to have anti-hypoxic, phytoestrogenic, anti-osteoporotic, anti-inflammatory, neuroprotective, and anti-depressant-like activities. Icariin is effective in the attenuation of AHR and chronic airway inflammatory changes in OVA-induced murine asthma model, and this effect is associated with regulation of Th17/Treg responses. Icariin inhibited NF-κB signaling activation and the NLRP3-inflammasome/caspase-1/IL-1β axis.Fórmula:C33H40O15Pureza:95%~99%Peso molecular:676.668Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Fórmula:C33H40O15Pureza:97.82% - 98.3%Forma y color:SolidPeso molecular:676.66Icariin
CAS:Fórmula:C33H40O15Pureza:≥ 96.0%Forma y color:Pale yellow to yellow powderPeso molecular:676.66Icariin
CAS:Natural glycosideFórmula:C33H40O15Pureza:≥ 90.0 % (HPLC)Forma y color:PowderPeso molecular:676.67Icariin
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications Icariin inhibits the ROS-dependent JNK and p38 pathways.<br>References Zhou, H., et al.: Exp. Ther. Med., 7, 1116 (2014)<br></p>Fórmula:C33H40O15Forma y color:NeatPeso molecular:676.66Icariin
CAS:<p>Icariin is a bioactive flavonoid compound, which is primarily derived from plants in the genus Epimedium, commonly known as Horny Goat Weed. This compound is a prenylated flavonol glycoside that is found in varying concentrations depending on the specific species of Epimedium used. Icariin exerts its effects through multiple biochemical pathways, most notably by inhibiting phosphodiesterase type 5 (PDE5), which leads to an increase in nitric oxide levels and the subsequent vasodilation of blood vessels.</p>Fórmula:C33H40O15Pureza:Min. 95%Forma y color:Slightly Yellow PowderPeso molecular:676.66 g/mol
