CAS 49745-95-1

Clorhidrato de dobutamina

Descripción:

Clorhidrato de dobutamina es una catecolamina sintética y un potente agente inotrópico que se utiliza principalmente en el tratamiento de la insuficiencia cardíaca y el shock cardiogénico. Actúa principalmente sobre los receptores adrenérgicos beta-1, lo que lleva a un aumento de la contractilidad miocárdica y a una mejora del gasto cardíaco sin aumentar significativamente la frecuencia cardíaca. La sustancia se administra típicamente por vía intravenosa debido a su rápido inicio de acción y corta vida media. Clorhidrato de dobutamina es un polvo cristalino blanco a blanco amarillento que es soluble en agua y tiene un rango de pH que es generalmente neutro. Su fórmula química es C18H23N3O3·HCl, y tiene un peso molecular de aproximadamente 345.86 g/mol. El compuesto se utiliza a menudo en entornos clínicos para la ecocardiografía de estrés y para manejar pacientes con insuficiencia cardíaca aguda. Al igual que con cualquier medicamento, es esencial monitorear a los pacientes por posibles efectos secundarios, incluyendo arritmias e hipotensión, durante su administración.

Fórmula: C₁₈H₂₃NO₃·ClH

InChI: InChI=1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H

Clave InChI: InChIKey=BQKADKWNRWCIJL-UHFFFAOYSA-N

SMILES: C(CNC(CCC1=CC=C(O)C=C1)C)C2=CC(O)=C(O)C=C2.Cl

Sinónimos:

• 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride
• 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride (1:1)
• 4-(2-{[4-(4-Hydroxyphenyl)Butan-2-Yl]Amino}Ethyl)Benzene-1,2-Diol Hydrochloride (1:1)
• <span class="text-smallcaps">DL</span>-Dobutamine hydrochloride
• Benzene-1,2-Diol Hydrochloride
• Dobutamine Hydrochloride
• Dobutrex
• Inotrex
• NSC 299583
• dl-Dobutamine hydrochloride

Dobutamine Hydrochloride

CAS: 34368-04-2, 49745-95-1

Fórmula: C₁₈H₂₃NO₃·HCl

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow to Light orange powder to crystal

Peso molecular: 337.84

Ref: 3B-D4335

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride is a catecholamine that acts as a -adrenergic receptor agonist. It has its strongest effects on 1 receptors, with lesser but significant 2 receptor activation and only weak 1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic,

Fórmula: C₁₈H₂₄ClNO₃

Forma y color: Powder, White to off-white

Peso molecular: 337.84

Ref: 02-J61333

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride

Fórmula: C₁₈H₂₃NO₃ / C₁₈H₂₃NO₃HCl

Pureza: 89.1% / 99.9%

Forma y color: Off-White

Peso molecular: 301.16779

Ref: 47-674

DOBUTAMINE HYDROCHLORIDE CRS

CAS: 49745-95-1

DOBUTAMINE HYDROCHLORIDE CRS

Ref: 41-D2954000

Dobutamine Hydrochloride

CAS: 49745-95-1

Amino-naphthols and other amino-phenols, their ethers and esters, other than those cont more than one kind of oxygen function; salts thereof nesoi

Fórmula: C₁₈H₂₃NO₃·HCl

Forma y color: White Off-White Crystalline Powder

Peso molecular: 337.14447

Ref: 45-1224507

Dobutamine Hydrochloride

CAS: 49745-95-1

Dobutamine Hydrochloride

Pureza: 98%

Peso molecular: 337.84g/mol

Ref: 54-OR1024667

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride

Pureza: ≥95%

Peso molecular: 337.84g/mol

Ref: 54-BUP11279

Dobutamine hydrochloride

CAS: 49745-95-1

Fórmula: C₁₈H₂₃NO₃HCl

Peso molecular: 337.85

Ref: 7W-GP1178

Dobutamine Hydrochloride

Producto controlado

CAS: 49745-95-1

Fórmula: C₁₈H₂₃NO₃·ClH

Forma y color: Neat

Peso molecular: 337.84

Ref: 86-MM0675.00

Dobutamine hydrochloride

CAS: 49745-95-1

Fórmula: C₁₈H₂₄ClNO₃

Pureza: 95%~99%

Peso molecular: 337.844

Ref: BP-BP4215

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride (Dobutamine (hydrochloride)) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.

Fórmula: C₁₈H₂₄ClNO₃

Pureza: 97.15% - 99.94%

Forma y color: Solid

Peso molecular: 337.84

Ref: TM-T8149

Dobutamine Hydrochloride RS

CAS: 49745-95-1

Forma y color: White To Very Pale Orange

Ref: 2K-1091000021

rac Dobutamine Hydrochloride

CAS: 49745-95-1

Stability Hygroscopic
Applications A sympathomimetic drug used to treat heart failure by inhibiting β1 receptors in the sympathetic nervous system. Cardiotonic.
References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005), Abdel F., et al.: J. Drug Res., 29, 83 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Fórmula: C₁₈H₂₃NO₃·ClH

Forma y color: Off-White

Peso molecular: 337.84

Ref: TR-D494445

Dobutamine Hydrochloride

CAS: 49745-95-1

Fórmula: C₁₈H₂₃NO₃HCl

Peso molecular: 301.38 : 36.46

Ref: ST-EA-CP-D59000

4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol hydrochloride

CAS: 49745-95-1

Dobutamine is a beta-adrenergic agonist that causes the heart to contract and increase blood pressure. It is used for pharmacological treatment of congestive heart failure and ventricular arrhythmias, as well as during angiography of the coronary arteries. Dobutamine stimulates dopamine receptors in the heart, which increases the systolic pressure. Dobutamine has been shown to be effective in improving myocardial contractility, left ventricle function, and cardiac output in patients with chronic congestive heart failure. This drug also improves left ventricular regional wall motion, papillary muscle function, and mitral valve regurgitation. Dobutamine may cause side effects such as nausea, vomiting, headache, or chest pain.

Fórmula: C₁₈H₂₄ClNO₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 337.84 g/mol

Ref: 3D-FH27507

Dobutamine hydrochloride

CAS: 49745-95-1

Fórmula: C₁₈H₂₄ClNO₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 337.84

Ref: 10-F240166