CAS 50-36-2

Cocaína

Descripción:

Cocaína, con el número CAS 50-36-2, es un potente estimulante y anestésico local derivado de las hojas de la planta de coca, Erythroxylum coca. Se clasifica como un alcaloide tropano y tiene una estructura química compleja, que presenta un marco bicíclico que incluye un átomo de nitrógeno. Cocaína es conocido por su capacidad para bloquear la recaptación de neurotransmisores, particularmente dopamina, norepinefrina y serotonina, lo que lleva a niveles aumentados de estas sustancias químicas en el cerebro, contribuyendo a sus efectos eufóricos. En su forma pura, Cocaína aparece como un polvo cristalino blanco o como un cristal sólido conocido como "crack" cuando se procesa. Es altamente adictivo y tiene un alto potencial de abuso, lo que conlleva varios riesgos para la salud, incluidos problemas cardiovasculares y efectos neurológicos. Cocaína también se utiliza en entornos médicos como anestésico local, particularmente en ciertos tipos de cirugía ocular, debido a sus propiedades vasoconstrictoras. Sin embargo, su uso recreativo es ilegal en muchos países y está clasificado como una sustancia controlada de la Lista II en los Estados Unidos.

Fórmula: C₁₇H₂₁NO₄

InChI: InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1

Clave InChI: InChIKey=ZPUCINDJVBIVPJ-LJISPDSOSA-N

SMILES: C(OC)(=O)[C@@H]1[C@@]2(N(C)[C@](C[C@@H]1OC(=O)C3=CC=CC=C3)(CC2)[H])[H]

Sinónimos:

• (-)-Cocaine
• (R)-Cocaine
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropane-2β-carboxylic acid, 3β-hydroxy-, methyl ester, benzoate (ester)
• 1αH,5αH-Tropane-2β-carboxylic acid, 3β-hydroxy-, methyl ester, benzoate (ester)
• 2β-Carbomethoxy-3β-(benzoyloxy)tropane
• 3β-Hydroxy-2β-tropanecarboxylic acid methyl ester benzoate (ester)
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, [1R-(exo,exo)]-
• <span class="text-smallcaps">L</span>-Cocaine
• Benzoylmethylecgonine
• Cocain
• Cocaina
• Ecgonine methyl ester benzoate (ester)
• Neurocaine
• l-Cocaine
• Bernice [Street Name]
• "C" Carrie
• Jam
• Star-spangled powder
• Cocaine [BAN]
• Dama blanca
• Gold dust [Street Name]
• Green gold
• UNII-I5Y540LHVR
• Blow [Street Name]
• methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
• Bernies
• Nose candy
• Pimp's drug
• Coke
• 1-alpha-H,5-alpha-H-Tropane-2-beta-carboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate
• Toot [Street Name]
• Eritroxilina
• 2-beta-Carbomethoxy-3-beta-benzoxytropane
• 2beta-Carbomethoxy-3beta-benzoxytropane
• Erytroxylin
• Star dust
• Kokayeen
• Cholly
• Corine
• 1-Cocaine
• Crack cocaine
• 3-(Benzoyloxy)-8-methyl-8-azabicyclo-(3.2.1)octane-2-carboxylic acid methyl ether
• 3beta-Hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylic acid methyl ester benzoate
• 2-beta-Tropanecarboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate (ester)
• Burese
• DEA No. 9041
• Kokan
• Cocaine, l-
• 3-Tropanylbenzoate-2-carboxylic acid methyl ester
• (1R,2R,3S,5S)-2-Methoxycarbonyltropan-3-yl benzoate
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R,2R,3S,5S)-
• Girl [Street Name]
• Rock [Street Name]
• Crack
• Snow
• White girl or lady
• Kokain
• Leaf
• HSDB 6469
• Happy trails
• Methyl 3-beta-hydroxy-1-alpha-H,5-alpha-H-tropane-2-beta-carboxylate benzoate (ester)
• Happy dust [Street Name]
• Methyl 3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester)
• Methyl Benzoylecgonine
• Lady [Street Name]
• Flake [Street Name]

Cocaine 0.1 mg/ml in Acetonitrile

Producto controlado

CAS: 50-36-2

Forma y color: Single Solution

Ref: 61-AMP1345.05-12

Cocaine

Producto controlado

CAS: 50-36-2

Forma y color: Neat

Ref: 61-FOR1345.05

Cocaine, 1mg/ml in Acetonitrile

Producto controlado

CAS: 50-36-2

Forma y color: Single Solution

Ref: LP-COC-156-FB-1LA

Cocaine

Producto controlado

CAS: 50-36-2

Forma y color: Neat

Ref: LP-COC-156-FB-10

Cocaine 1.0 mg/ml in Acetonitrile

Producto controlado

CAS: 50-36-2

Forma y color: Single Solution

Ref: 61-AMP1345.05-11

L-Cocaine

Producto controlado

CAS: 50-36-2

Applications L-Cocaine, inhibits the dopamine, norepinephrine, and serotonin transporters. Unlike amphetamines, it has no effect on catecholamine release. Controlled substance. Anesthetic (local).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blakely, R.D., et al.: Curr. Opin. Neurobiol., 10, 328 (2000); Cowell, R. M., et al.: Eur. J. Pharmacol., 389, 59 (2000); Fleckenstein, A.E., Eur. J. Pharmacol., 406, 1 (2000), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003);

Fórmula: C₁₇H₂₁NO₄

Forma y color: Neat

Peso molecular: 303.35

Ref: TR-C633495

L-Cocaine (1 mg/ml in Methanol)

Producto controlado

CAS: 50-36-2

Fórmula: C₁₇H₂₁NO₄

Forma y color: Single Solution

Peso molecular: 303.35

Ref: TR-KIT2480

Cocaine

Producto controlado

CAS: 50-36-2

Cocaine is a small-molecule drug that acts as an indirect agonist to the neurotransmitter dopamine, which is involved in reward and motivation. Cocaine binds to the response element in the promoter region of the gene for the enzyme human erythrocyte membrane protein band 3 (hEPB3). This binding inhibits transcription of hEPB3 mRNA by preventing RNA polymerase from reading through to the start codon. Cocaine also prevents reuptake of catecholamines, which prolongs their effects on postsynaptic cells. Cocaine has been used as a pharmacological treatment for attention deficit hyperactivity disorder, although it is not currently approved by the FDA for this use. The physiological effects of cocaine are similar to those seen with other stimulants such as amphetamine and methyl ethylamphetamine. These include increased heart rate and blood pressure, anxiety, insomnia, paranoia, anorexia, and reduced pain sensitivity.

Fórmula: C₁₇H₂₁NO₄

Pureza: Min. 95%

Peso molecular: 303.35 g/mol

Ref: 3D-FC111889