CAS 500-38-9

Ácido nordihidroguaiarético

Descripción:

Ácido nordihidroguaiarético (NDGA) es un compuesto fenólico que se encuentra de forma natural, derivado principalmente del arbusto de creosota (Larrea tridentata). Se caracteriza por sus propiedades antioxidantes, que se atribuyen a su capacidad para eliminar radicales libres e inhibir la peroxidación lipídica. NDGA tiene una fórmula molecular de C15H14O4 y presenta una estructura compleja que incluye dos grupos metoxi y un moiety de catecol. Este compuesto ha sido estudiado por sus posibles aplicaciones terapéuticas, incluyendo efectos antiinflamatorios y anticancerígenos, aunque su uso es limitado debido a la toxicidad potencial y los efectos secundarios. NDGA también es conocido por exhibir propiedades antimicrobianas y se ha investigado por su papel en la conservación de alimentos. En términos de solubilidad, es moderadamente soluble en disolventes orgánicos, pero menos en agua. Debido a su estructura química única y actividad biológica, NDGA sigue siendo de interés tanto en la investigación farmacológica como en aplicaciones industriales. Sin embargo, las consideraciones de seguridad y regulación son esenciales al manipular este compuesto.

Fórmula: C₁₈H₂₂O₄

InChI: InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3

Clave InChI: InChIKey=HCZKYJDFEPMADG-UHFFFAOYSA-N

SMILES: C(C(C(CC1=CC(O)=C(O)C=C1)C)C)C2=CC(O)=C(O)C=C2

Sinónimos:

• 1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane
• 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis(pyrocatechol)
• 4,4'-(2,3-Dimethyltetramethylen)dibrenzcatechin
• 4,4'-(2,3-Dimethyltetramethylene)Dipyrocatechol
• 4,4'-(2,3-Dimetiltetrametilen)Dipirocatecol
• 4,4′-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol]
• 4-[4-(3,4-Dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
• Butane, 1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethyl-
• Dihydronorguaiaretic acid
• Dinorguaiaretic acid, dihydro-
• Ndga
• Nordihydroguaiaretic acid
• Nordihydroguaiaretinsaeure
• Norguaiaretic acid, dihydro-
• Nsc 4291
• Pyrocatechol, 4,4'-(2,3-dimethyltetramethylene)di-
• β,γ-Dimethyl-α,δ-bis(3,4-dihydroxyphenyl)butane
• 1,2-Benzenediol, 4,4′-(2,3-dimethyl-1,4-butanediyl)bis-
• 4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]dibenzene-1,2-diol
• NDGA, Larrea divaricata

Nordihydroguaiaretic acid, 97%

CAS: 500-38-9

Nordihydroguaiaretic acid is used in the treatment of multiple diseases, including cardiovascular diseases, neurological disorders and cancers. It is also used as an antioxidant. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentatio

Fórmula: C₁₈H₂₂O₄

Pureza: 97%

Forma y color: Crystals or powder or crystalline powder, White to cream to pale brown to pale yellow

Peso molecular: 302.37

Ref: 02-L03149

Nordihydroguaiaretic acid

CAS: 500-38-9

Nordihydroguaiaretic acid analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₈H₂₂O₄

Pureza: (HPLC) ≥95%

Forma y color: Powder

Peso molecular: 302.38

Ref: 11-6135

Nordihydroguaiaretic acid

CAS: 500-38-9

Fórmula: C₁₈H₂₂O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 302.3649

Ref: IN-DA003TAG

Nordihydroguaiaretic Acid

CAS: 500-38-9

Nordihydroguaiaretic Acid

Pureza: 95%

Peso molecular: 302.36g/mol

Ref: 54-OR1023910

Nordihydroguaiaretic acid

CAS: 500-38-9

Nordihydroguaiaretic acid

Pureza: ≥80%

Peso molecular: 302.36g/mol

Ref: 54-BUP14743

Nordihydroguaiaretic acid

CAS: 500-38-9

Fórmula: C₁₈H₂₂O₄

Pureza: ≥ 97.0%

Forma y color: White to off-white or faint yellow-beige powder or crystals

Peso molecular: 302.37

Ref: 7W-GE5483

Nordihydroguaiaretic Acid

CAS: 500-38-9

Fórmula: C₁₈H₂₂O₄

Pureza: >97.0%(HPLC)

Forma y color: White to Orange to Green powder to crystal

Peso molecular: 302.37

Ref: 3B-D0800

GB 5009.32-2016 Antioxidants Mixture 161 1000 mg/L in Acetonitrile

Producto controlado

CAS: 1034-01-1, 1166-52-5, 121-79-9, 128-37-0, 1421-63-2, 1948-33-0, 25013-16-5, 500-38-9, 88-26-6

Forma y color: Mixture

Ref: 04-A50000161AL

Nordihydroguaiaretic Acid

CAS: 500-38-9

Fórmula: C₁₈H₂₂O₄

Forma y color: Neat

Peso molecular: 302.36

Ref: 04-C15644200

Nordihydroguaiaretic acid

CAS: 500-38-9

Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.

Fórmula: C₁₈H₂₂O₄

Pureza: 97.82% - 99.91%

Forma y color: Solid

Peso molecular: 302.36

Ref: TM-TJS2190

Nordihydroguaiaretic acid

CAS: 500-38-9

Polyphenol

Fórmula: C₁₈H₂₂O₄

Pureza: ≥ 98.0 % (HPLC)

Forma y color: Powder

Peso molecular: 302.37

Ref: 5G-82880

Nordihydro Guaiaretic Acid (mixture of diastereomers)

Producto controlado

CAS: 500-38-9

Applications Nordihydro Guaiaretic Acid is a lipoxygenase inhibitor; polyphenol-bearing o-dihydroxy (catechol) structure. Inhibitor of broad bean lipoxygenase. The oxidation product from Resveratrol (R150000) showed a high inhibitory activity, whereas Resveratrol itself had no activity and its oxidation efficiency was low.
References Brash, A., et al.: J. Biol. Chem., 274, 23679 (1999), Fujimoto, A., et al.: Bioorg. Med. Chem. Lett., 20, 7393 (2010), Ridolfi, M., et al.: J. Agric. Food Chem., 50, 835 (2002),

Fórmula: C₁₈H₂₂O₄

Forma y color: White To Brown

Peso molecular: 302.36

Ref: TR-N673000

Nordihydroguaiaretic acid - mixture of diastereomers

CAS: 500-38-9

Nordihydroguaiaretic acid - mixture of diastereomers is a potent antioxidant compound, regarded as a lignan. This compound is primarily sourced from the creosote bush, known scientifically as *Larrea tridentata*. The mode of action of nordihydroguaiaretic acid involves its ability to scavenge free radicals, effectively neutralizing them and thus protecting cellular components from oxidative damage.

Fórmula: C₁₈H₂₂O₄

Forma y color: Powder

Peso molecular: 302.36 g/mol

Ref: 3D-FN26437

Nordihydroguaiaretic acid

CAS: 500-38-9

Nordihydroguaiaretic acid is a lignan-type compound, which is a naturally occurring product primarily sourced from the resin of the creosote bush, *Larrea tridentata*. It functions as a powerful antioxidant through the inhibition of lipid peroxidation and scavenging of free radicals, thereby preventing oxidative stress in biological systems.

Fórmula: C₁₈H₂₂O₄

Peso molecular: 302.37 g/mol

Ref: 3D-N-8500