CAS 500-62-9

Yangonina

Descripción:

Yangonina es un compuesto natural clasificado como un derivado de benzopirano, que se encuentra principalmente en la especie vegetal *Piper methysticum*, comúnmente conocida como kava. Se reconoce por sus propiedades psicoactivas y se ha estudiado por sus posibles efectos terapéuticos, particularmente en relación con la ansiedad y el alivio del estrés. Yangonina exhibe una estructura química única que contribuye a su actividad biológica, incluyendo interacciones con el sistema endocannabinoide. Se conoce que el compuesto tiene una naturaleza lipofílica, lo que le permite cruzar fácilmente las membranas biológicas. En términos de solubilidad, Yangonina es generalmente soluble en disolventes orgánicos, pero tiene una solubilidad limitada en agua. Su perfil farmacológico sugiere que puede influir en los sistemas de neurotransmisores, aunque se necesita más investigación para elucidar completamente sus mecanismos de acción y posibles beneficios para la salud. Al igual que con muchos productos naturales, la seguridad y eficacia de Yangonina en aplicaciones clínicas requieren una cuidadosa consideración y una investigación adicional.

Fórmula: C₁₅H₁₄O₄

InChI: InChI=1S/C15H14O4/c1-17-12-6-3-11(4-7-12)5-8-13-9-14(18-2)10-15(16)19-13/h3-10H,1-2H3/b8-5+

Clave InChI: InChIKey=XLHIYUYCSMZCCC-VMPITWQZSA-N

SMILES: C(=C/C1=CC=C(OC)C=C1)\C2=CC(OC)=CC(=O)O2

Sinónimos:

• (E)-4-Methoxy-6-[2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one
• 2H-Pyran-2-one, 4-methoxy-6-(p-methoxystyryl)-
• 2H-Pyran-2-one, 4-methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-
• 2H-Pyran-2-one, 4-methoxy-6-[2-(4-methoxyphenyl)ethenyl]-, (E)-
• 2H-pyran-2-one, 4-methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]-
• 4-Methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one
• 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]-2H-pyran-2-on
• 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]-2H-pyran-2-one
• 4-Methoxy-6-[b-(p-anisyl)vinyl]-a-pyrone
• 4-Méthoxy-6-[(E)-2-(4-méthoxyphényl)éthènyl]-2H-pyran-2-one
• 5-Hydroxy-3-methoxy-7-(p-methoxyphenyl)-2,4,6-heptatrienoic Acid d-Lactone
• 6-(p-Methoxystyryl)-4-methoxy-a-pyrone

Yangonin

CAS: 500-62-9

Yangonin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₅H₁₄O₄

Pureza: (HPLC) ≥95%

Forma y color: Powder

Peso molecular: 258.27

Ref: 11-4989

Yangonin

CAS: 500-62-9

Fórmula: C₁₅H₁₄O₄

Peso molecular: 258.27

Ref: 7W-GY4353

yangonin

CAS: 500-62-9

yangonin

Pureza: ≥98%

Peso molecular: 258.27g/mol

Ref: 54-BUP05071

Yangonin

CAS: 500-62-9

Fórmula: C₁₅H₁₄O₄

Pureza: 95%~99%

Peso molecular: 258.273

Ref: BP-BP1460

yangonin

CAS: 500-62-9

Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.

Fórmula: C₁₅H₁₄O₄

Pureza: 98.82% - 99.55%

Forma y color: Pale Yellow Powder

Peso molecular: 258.27

Ref: TM-T3S0738

Yangonin

CAS: 500-62-9

Fórmula: C₁₅H₁₄O₄

Peso molecular: 258.27

Ref: 4Z-Y-007001

Yangonin

CAS: 500-62-9

Lactone

Fórmula: C₁₅H₁₄O₄

Pureza: ≥ 95.0 % (HPLC)

Forma y color: Powder

Peso molecular: 258.27

Ref: 5G-89293

Yangonin

Producto controlado

CAS: 500-62-9

Applications A lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Fórmula: C₁₅H₁₄O₄

Forma y color: Neat

Peso molecular: 258.27

Ref: TR-Y100550

Yangonin

CAS: 500-62-9

Yangonin is a kavalactone, which is a type of compound found in the roots of the Piper methysticum plant, commonly known as kava. This product is derived through the extraction of kavalactones from the kava root, a process that isolates its active psychoactive components. Yangonin is known for its interaction with the brain's neuroreceptor systems, particularly the cannabinoid CB1 receptors. This interaction may contribute to its psychoactive effects, influencing mood and perception.

Fórmula: C₁₅H₁₄O₄

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 258.27 g/mol

Ref: 3D-FY137901

Yangonin-d3

Producto controlado

CAS: 500-62-9

Applications Isotope labelled analog of Yangonin (Y100550), a lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Fórmula: C₁₅H₁₁D₃O₄

Forma y color: Neat

Peso molecular: 261.29

Ref: TR-Y100552