CAS 51-15-0

cloruro de pralidoxima

Descripción:

cloruro de pralidoxima, con el número CAS 51-15-0, es un compuesto químico utilizado principalmente como antídoto para el envenenamiento por organofosforados, particularmente en casos de exposición a agentes nerviosos. Funciona reactivando la acetilcolinesterasa, una enzima inhibida por los organofosforados, restaurando así la neurotransmisión normal. El compuesto es una sal de amonio cuaternario, lo que contribuye a su solubilidad en agua y limita su capacidad para cruzar la barrera hematoencefálica. cloruro de pralidoxima se administra típicamente por inyección y a menudo se utiliza junto con atropina para contrarrestar los efectos de la toxicidad colinérgica. Su estructura química incluye un anillo de piridina y un grupo hidroxilo, que son esenciales para su mecanismo de reactivación. La sustancia se considera generalmente que tiene un perfil de baja toxicidad cuando se usa adecuadamente, pero puede causar efectos secundarios como debilidad muscular o problemas respiratorios si se usa incorrectamente. El almacenamiento y manejo adecuados son cruciales, ya que debe mantenerse en un lugar fresco y seco, alejado de sustancias incompatibles.

Fórmula: C₇H₉N₂O·Cl

InChI: InChI=1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H

Clave InChI: InChIKey=HIGSLXSBYYMVKI-UHFFFAOYSA-N

SMILES: C(=NO)C=1[N+](C)=CC=CC1.[Cl-]

Sinónimos:

• (E)-(1-methylpyridin-2(1H)-ylidene)-N-oxomethanaminium chloride
• 1-Methyl-2-aldoximinopyridinium chloride
• 1-Methylpyridinium-2-aldoxime chloride
• 2-Formyl-1-methylpyridinium chloride oxime
• 2-Hydroxyiminomethyl-1-Methylpyridinium Chloride
• 2-PAM chloride
• 2-Pralidoxime chloride
• 2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium chloride
• 2-[(Hydroxyimino)methyl]-1-methylpyridin-1-ium chloride
• N-Methylpyridinium-2-aldoxime chloride
• N-Methylpyridinium-2-carboxaldoxime chloride
• Pralidoxime chloride
• Protopam chloride
• Pyraloxime Methylchloride
• Pyridine-2-aldoxime methochloride
• Pyridine-2-carbaldoxime methochloride
• Pyridinium, 2-[(hydroxyimino)methyl]-1-methyl-, chloride
• Pyridinium, 2-[(hydroxyimino)methyl]-1-methyl-, chloride (1:1)
• Pyridinium, 2-formyl-1-methyl-, chloride, oxime

1-Methylpyridinium-2-aldoxime Chloride

CAS: 51-15-0

Fórmula: C₇H₉ClN₂O

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 172.61

Ref: 3B-M0819

Pyridine-2-carboxaldoxime methochloride, 97%

CAS: 51-15-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₇H₉ClN₂O

Pureza: 97%

Forma y color: Crystals or powder or crystalline powder or fused/lumpy solid, White to pale cream

Peso molecular: 172.61

Ref: 02-B23890

Pralidoxime Chloride

CAS: 51-15-0

Pralidoxime Chloride (2-PAM chloride) is a agent in the treatment of organophosphate poisoning, which binds to organophosphate-inactivated acetylcholinesterase.

Fórmula: C₇H₉ClN₂O

Pureza: 99.84%

Forma y color: Solid

Peso molecular: 172.61

Ref: TM-T1111

1-​Methylpyridinium-​2-​aldoxime chloride

CAS: 51-15-0

Fórmula: C₇H₉ClN₂O

Pureza: 98%

Forma y color: Solid

Peso molecular: 172.6122

Ref: IN-DA003HX2

Pyridine-2-aldoxime methochloride

CAS: 51-15-0

Fórmula: C₇H₉N₂O·Cl

Pureza: ≥ 98.0%

Forma y color: White to off-white or light yellow crystalline powder

Peso molecular: 172.61

Ref: 7W-GE1467

Pralidoxime Chloride

CAS: 51-15-0

Pralidoxime Chloride

Pureza: ≥98%

Peso molecular: 172.61g/mol

Ref: 54-BUP17362

2-((Hydroxyimino)Methyl)-1-Methylpyridin-1-Ium Chloride

CAS: 51-15-0

2-((Hydroxyimino)Methyl)-1-Methylpyridin-1-Ium Chloride

Pureza: 99%

Peso molecular: 172.61g/mol

Ref: 54-OR1009629

Pralidoxime Chloride

CAS: 51-15-0

Forma y color: Neat

Ref: 86-MM1067.00

Pralidoxime Chloride

CAS: 51-15-0

Fórmula: C₇H₉N₂O·Cl

Peso molecular: 137.16 35.45

Ref: 4Z-P-253001

Pralidoxime Chloride

Producto controlado

CAS: 51-15-0

Applications This compound binds to inactivated acetylcholinesterases and is used to combat poisoning from organophosphates and nerve agents
References Lajmanovich, R., et al.: Toxicol. Env. Chem., 90, 1145 (2008), Eyer, P., et al.: Brit. J. Clin. Pharmacol., 66, 450 (2008), Goncalves, L., et al.: J. Pharm. Sci., 98, 1040 (2009),

Fórmula: C₇H₉N₂O·Cl

Forma y color: White Solid

Peso molecular: 172.61

Ref: TR-P701120

Pralidoxime chloride - Bio-X ™

CAS: 51-15-0

Pralidoxime is a cholinesterase reactivator that is used for the treatment of organophosphate poisoning. When organophosphate binds to the esteratic site of acetylcholinesterase, it results in a reversible inactivation of the enzyme. However, by rupturing the phosphate-ester link that has been formed between the organophosphate and acetylcholinesterase, pralidoxime is able to reactivate the cholinesterase enzyme.

Fórmula: C₇H₉ClN₂O

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 172.61 g/mol

Ref: 3D-BP164283

Pralidoxime chloride

CAS: 51-15-0

Reactivates acetylcholinesterases; treats organophosphate poisoning

Fórmula: C₇H₉ClN₂O

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 172.61 g/mol

Ref: 3D-FP27115

2-[(1E)-(hydroxyimino)methyl]-1-methylpyridin-1-ium chloride

CAS: 51-15-0

Fórmula: C₇H₉ClN₂O

Pureza: ≥98%(HPLC)

Peso molecular: 172.61

Ref: 10-F358359

Pralidoxime Chloride

CAS: 51-15-0

Fórmula: C₇H₉N₂OCl

Peso molecular: 137.16 : 35.45

Ref: ST-EA-CP-P187001