CAS 51-48-9

(-)-Tiroxina

Descripción:

(-)-Tiroxina, también conocido como L-tiroxina o T4, es una hormona producida por la glándula tiroides que juega un papel crucial en la regulación del metabolismo, el crecimiento y el desarrollo en el cuerpo. Es un derivado tetraiodado del aminoácido tirosina, caracterizado por la presencia de cuatro átomos de yodo en su estructura. La fórmula química de (-)-Tiroxina es C15H11I4N0, y tiene un peso molecular de aproximadamente 776.87 g/mol. Este compuesto se encuentra típicamente como un polvo cristalino blanco a blanco amarillento y es soluble en agua y alcohol, pero menos soluble en disolventes orgánicos. (-)-Tiroxina funciona al unirse a los receptores de hormonas tiroideas, influyendo en la expresión génica y los procesos metabólicos. Se utiliza comúnmente en entornos clínicos para tratar el hipotiroidismo y otros trastornos relacionados con la tiroides. Su actividad se monitorea de cerca, ya que tanto la deficiencia como el exceso pueden llevar a problemas de salud significativos. El número CAS 51-48-9 identifica de manera única este compuesto en bases de datos químicas, facilitando la investigación y el cumplimiento normativo.

Fórmula: C₁₅H₁₁I₄NO₄

InChI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1

Clave InChI: InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N

SMILES: O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(C[C@@H](C(O)=O)N)C=C2I

Sinónimos:

• (-)-Thyroxine
• 3,3',5,5'-Tetraiodo-L-thyronine
• 3,3′,5,5′-Tetraiodo-<span class="text-smallcaps">L</span>-thyronine
• 3,5,3',5'-Tetraiodothyronine
• 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-alanine
• <span class="text-smallcaps">L</span>-T₄
• <span class="text-smallcaps">L</span>-Thyroxin
• <span class="text-smallcaps">L</span>-Thyroxine
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
• Beta-[(3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl]Alanine
• DL-thyroxin
• DL-thyroxine
• DL-tiroxina
• Henning
• L-3,5,3',5'-Tetraiodothyronine
• L-T4
• L-Thyroxin
• L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
• Levothyroxine
• Levotiron
• Nsc 36397
• O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosin
• O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodotyrosine
• O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-<span class="text-smallcaps">L</span>-tyrosine
• O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
• SK&amp;F 1-6528
• T4
• T4(Hormone)
• T₄
• T₄ (hormone)
• THX
• Tetraiodothyronine
• Thyrax
• Thyreoideum
• Thyroxin
• Thyroxinal
• Thyroxine, <span class="text-smallcaps">L</span>-

Levothyroxine

CAS: 51-48-9

Amino-acid derivatives

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: Yellow Off-White Crystalline Powder

Peso molecular: 776.6867

Ref: 45-1365000

L-Thyroxine, 98%

CAS: 51-48-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: 98%

Forma y color: Powder, Pale cream to cream

Peso molecular: 776.87

Ref: 02-J62606

LIOTHYRONINE FOR PEAK IDENTIFICATION CRS

CAS: 1041-01-6, 300-39-0, 51-24-1, 51-48-9, 67-30-1

LIOTHYRONINE FOR PEAK IDENTIFICATION CRS

Fórmula: C₁₅H₁₁I₃NNaO₄

Forma y color: Added

Peso molecular: 672.9553

Ref: 41-Y0000860

L-Thyroxine

CAS: 51-48-9

L-Thyroxine

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: ≥95%

Peso molecular: 776.87

Ref: 54-BUP17744

L-Thyroxine

CAS: 51-48-9

L-Thyroxine, major thyroid hormone, is made by iodinating tyrosine and coupling it in thyroglobulin, then secreted into blood.

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: 97.63% - 99.56%

Forma y color: Crystals Solid

Peso molecular: 776.87

Ref: TM-T0864

L-Thyroxine

CAS: 51-48-9

L-Thyroxine

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: >97%

Forma y color: Solid

Peso molecular: 776.87

Ref: 54-OR1030066

L-Thyroxine (Liothyronine EP Impurity A, Levothyroxine, Tetraiodothyronine)

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: White To Off-White Solid

Peso molecular: 776.87

Ref: 4Z-T-421

L-Thyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: ≥ 98.0% (dried basis)

Forma y color: White to off-white crystalline powder

Peso molecular: 776.87

Ref: 7W-GP9966

L-Thyroxine

Producto controlado

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: Neat

Peso molecular: 776.87

Ref: 04-C17575300

L-Thyroxine (Standard)

CAS: 51-48-9

L-Thyroxine (Standard) is the standard substance of L-Thyroxine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: Solid

Peso molecular: 776.87

Ref: TM-TMSM-1492

O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: 97%

Forma y color: Liquid

Peso molecular: 776.8700

Ref: IN-DA0038OW

Thyroxine

Producto controlado

CAS: 51-48-9

Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: Neat

Peso molecular: 776.87

Ref: TR-T425600

Levothyroxine Lactose Adduct >85%

Producto controlado

CAS: 51-48-9

Fórmula: C₂₇H₃₁I₄NO₁₄

Pureza: >85%

Forma y color: Neat

Peso molecular: 1101.151

Ref: TR-L378053

Thyroxine (100% pure T4 reference standard (free of T3))

CAS: 51-48-9

Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: Neat

Peso molecular: 776.87

Ref: TR-T425650

Levothyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Peso molecular: 776.87

Ref: ST-EA-CP-L18000

Liothyronine EP Impurity A

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Peso molecular: 776.9

Ref: ST-EA-CP-L45001

L-Thyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: Solid

Peso molecular: 776.87

Ref: BE-BePure-26042

L-Thyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: Solid

Peso molecular: 776.87

Ref: BE-MU-2445

L-Thyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: Solid

Peso molecular: 776.87

Ref: BE-RMCT176001

L-Thyroxine-[13C6] Hydrochloride(T4)

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Forma y color: Solid

Peso molecular: 776.87

Ref: BE-MC-2535C6