CAS 51481-61-9
:Cimetidina
Descripción:
Cimetidina es un antagonista del receptor H2 de histamina que se utiliza principalmente para reducir la producción de ácido estomacal, siendo efectivo en el tratamiento de condiciones como úlceras pépticas, enfermedad por reflujo gastroesofágico (ERGE) y síndrome de Zollinger-Ellison. Su fórmula química es C10H13N5S, y presenta un grupo tiourea, que es crucial para su actividad farmacológica. Cimetidina es conocido por su capacidad para inhibir la secreción de ácido gástrico al bloquear la acción de la histamina en los receptores H2 de las células parietales en el revestimiento del estómago. Además, tiene una vida media relativamente corta y se metaboliza en el hígado, con cierto potencial de interacciones medicamentosas debido a su efecto sobre las enzimas del citocromo P450. Los efectos secundarios comunes pueden incluir mareos, dolor de cabeza y trastornos gastrointestinales. Cimetidina también es notable por sus efectos antiandrogénicos, que pueden llevar a ginecomastia en algunos pacientes. En general, sigue siendo un medicamento significativo en el manejo de trastornos relacionados con el ácido, aunque a menudo se prefieren agentes más nuevos con menos efectos secundarios en la práctica clínica.
Fórmula:C10H16N6S
InChI:InChI=1/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
Clave InChI:InChIKey=AQIXAKUUQRKLND-UHFFFAOYSA-N
SMILES:C(SCCN=C(NC#N)NC)C1=C(C)N=CN1
Sinónimos:- 1-Cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
- 2-Cyano-1-Methyl-3-(2-(((5-Methylimidazol-4-Yl)Methyl)Thio)Ethyl)Guanidine
- Acibilin
- Acinil
- Biomet
- Cimal
- Cimetag
- Cimetidin
- Cimetidina
- Cimetidine (base or and unspecifieds salts)
- Cimetidine A
- Cimetidine AB
- Cimetum
- Dyspamet
- Edalene
- Eureceptor
- Fremet
- Gastromet
- Guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-
- Guanidine, N-cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-
- Histodil
- N-Cyano-N'-methyl-N''-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidine
- N-Cyano-N′′-methyl-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine
- Nsc 335308
- Peptol
- Skf 92334
- Tagamet
- Tagamet HB
- Tagamet HB 200
- Tamagret
- Tametin
- Tratul
- Ulcedin
- Ulcedine
- Ulcerex
- Ulcerfen
- Ulcimet
- Ulcofalk
- Ulcomedina
- Ulcomet
- Ulhys
- Cimetidine
- CIMETIDINE A TYPE
- FPF 1002
- N-CYANO-N'-METHYL-N''-[[2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]THIO]ETHYL]GUANIDINE
- CIMITIDINE
- ALTRAMET
- 2-CYANO-1-METHYL-3-[2-(5-METHYL-1H-IMIDAZOL-4-YL-METHYLTHIO)ETHYL]GUANIDINE
- Ver más sinónimos
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Encontrado 22 productos.
Cimetidine
CAS:Fórmula:C10H16N6SPureza:>99.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:252.34Cimetidine, 98+%
CAS:<p>Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the g</p>Fórmula:C10H16N6SPureza:98+%Forma y color:White to off-white, PowderPeso molecular:252.34CIMETIDINE FOR PEAK IDENTIFICATION CRS
CAS:<p>CIMETIDINE FOR PEAK IDENTIFICATION CRS</p>Fórmula:C10H16N6SPeso molecular:252.3392Cimetidine
CAS:CimetidineFórmula:C10H16N6SPureza:99.6%Forma y color:White SolidPeso molecular:252.11572Cimetidine
CAS:Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoiFórmula:C10H16N6SForma y color:White Off-White Crystalline PowderPeso molecular:252.11572(Z)-3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
CAS:Fórmula:C10H16N6SPureza:98%Forma y color:SolidPeso molecular:252.3392Cimetidine
CAS:<p>Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS.</p>Fórmula:C10H16N6SPureza:99.82%Forma y color:Crystals Physical Description White Crystals With A Slight Sulfur-Mercaptan Odor (Ntp 1992)Peso molecular:252.34Cimetidine, USP grade
CAS:Fórmula:C10H16N6SPureza:≤ 0.2%Forma y color:White crystalline powderPeso molecular:252.34Cimetidine
CAS:Fórmula:C10H16N6SPureza:99.0 - 101.0 %Forma y color:White to off-white powderPeso molecular:252.34Cimetidine 100 µg/mL in Acetonitrile
CAS:Fórmula:C10H16N6SForma y color:Single SolutionPeso molecular:252.34Cimetidine
CAS:<p>Cimetidine is a histamine-2 receptor antagonist that inhibits gastric acid secretion and reduces the activity of stomach enzymes. It is used to treat peptic ulcers, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. Cimetidine has been shown to inhibit the activity of drug-metabolizing enzymes such as cytochrome P450. Cimetidine also inhibits the transport protein P-glycoprotein (P-gp), which leads to increased concentrations of some drugs in the blood and tissues. This inhibition may lead to an increase in cardiac effects with certain drugs, such as x-ray diffraction data with taxol or h1 antagonists.</p>Fórmula:C10H16N6SPureza:Min. 95%Forma y color:White PowderPeso molecular:252.34 g/molN-Cyano-N’-methyl-N”-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine
CAS:Fórmula:C10H16N6SPureza:98%Forma y color:SolidPeso molecular:252.34
![(Z)-3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00I97O.jpg&w=3840&q=75)
![N-Cyano-N’-methyl-N”-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF224139.jpg&w=3840&q=75)
