CAS 516-05-2

Ácido metilmalónico

Descripción:

Ácido metilmalónico (MMA) es un ácido dicarboxílico con la fórmula química C5H8O4 y un número CAS de 516-05-2. Es un sólido cristalino incoloro que es soluble en agua y en disolventes orgánicos polares. El MMA se caracteriza por la presencia de dos grupos ácidos carboxílicos (-COOH) y una cadena de carbono ramificada, lo que contribuye a su reactividad y significado biológico. Juega un papel crucial en el metabolismo, particularmente en la conversión de ciertos aminoácidos y ácidos grasos, y es un intermediario clave en el metabolismo de la vitamina B12. Niveles elevados de Ácido metilmalónico en el cuerpo pueden indicar una deficiencia de vitamina B12, lo que lleva a varios trastornos metabólicos. Además de su importancia biológica, Ácido metilmalónico también se utiliza en síntesis orgánica y como un bloque de construcción para varios compuestos químicos. Sus derivados tienen aplicaciones en farmacéutica y ciencia de materiales, destacando su versatilidad en contextos biológicos e industriales.

Fórmula: C₄H₆O₄

InChI: InChI=1/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)/p-2

Clave InChI: InChIKey=ZIYVHBGGAOATLY-UHFFFAOYSA-N

SMILES: C(C(O)=O)(C(O)=O)C

Sinónimos:

• 1,1-Ethanedicarboxylic acid
• 2-Methylmalonic acid
• 2-Methylpropanedioic acid
• Acide Methylmalonique
• Acido Metilmalonico
• Isosuccinic acid
• Malonic acid, methyl-
• Methylmalonic Acid
• Methylmalonsaeure
• Methylpropanedioic acid
• Nsc 25201
• Propanedioic acid, 2-methyl-
• Propanedioic acid, methyl-
• 3-methoxy-3-oxopropanoic acid
• methylpropanedioate
• Methylmalonicacid
• Methyl (Ethoxy Methylene) Cyanoacetate
• isosuccinicacid
• Methylmalonic
• methyl-malonicaci
• 2-methylmalonicacid
• 1,1-ethanedicarboxylicacid

Methylmalonic Acid

CAS: 516-05-2

Fórmula: C₄H₆O₄

Pureza: >98.0%(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 118.09

Ref: 3B-M0568

2-Methylmalonic acid

CAS: 516-05-2

Fórmula: C₄H₆O₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 118.0880

Ref: IN-DA003S46

Methylmalonic acid

CAS: 516-05-2

Methylmalonic acid

Pureza: ≥95%

Peso molecular: 118.09g/mol

Ref: 54-BUP18432

Methylmalonic acid

CAS: 516-05-2

Methylmalonic acid

Pureza: 97%

Forma y color: Solid

Peso molecular: 118.09g/mol

Ref: 54-OR911347

2-Methylmalonic acid 100 µg/mL in Acetonitrile

CAS: 516-05-2

Fórmula: C₄H₆O₄

Forma y color: Single Solution

Peso molecular: 118.09

Ref: 04-A15089080AL-100

Methylmalonic Acid

CAS: 516-05-2

Fórmula: C₄H₆O₄

Peso molecular: 118.09

Ref: 4Z-M-213001

Methylmalonic acid

CAS: 516-05-2

Methylmalonic acid (Isosuccinic acid) is a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A.

Fórmula: C₄H₆O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 118.09

Ref: TM-T4817

Methylmalonic Acid

Producto controlado

CAS: 516-05-2

Applications Binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.
References Pedersen, T., et al.: J. Chromatogr., B: Anal. Technol. Biomed. Life Sci., 879, 1502 (2011),

Fórmula: C₄H₆O₄

Forma y color: Neat

Peso molecular: 118.09

Ref: TR-M318860

Methylmalonic acid

CAS: 516-05-2

Methylmalonic acid is a metabolite of the vitamin B12. It is formed from homocysteine via the enzyme methylmalonyl-CoA mutase, which converts it to methylmalonic acid. Methylmalonic acid can be detected in the blood and urine and is used as a diagnostic tool for metabolic diseases such as bowel disease and cobalamin deficiency. The rate constant (k) for the conversion of methylmalonic acid to methylmalonate has been determined by gas chromatography with mass spectrometry analysis. The analytical method involves derivatization with an organic solvent, followed by chromatographic analysis. This compound has been shown to cause neuronal death in rats and may lead to peripheral neuropathy in humans.

Fórmula: C₄H₆O₄

Forma y color: Powder

Peso molecular: 118.09 g/mol

Ref: 3D-FM25870

Methylmalonic acid

CAS: 516-05-2

Fórmula: C₄H₆O₄

Pureza: 95%

Forma y color: Solid, Crystalline

Peso molecular: 118.088

Ref: 10-F080319