CAS 52-67-5

(-)-Penicilamina

Descripción:

(-)-Penicilamina es un agente quelante y un derivado de la penicilina, utilizado principalmente en el tratamiento de condiciones como la artritis reumatoide y la enfermedad de Wilson, donde ayuda a eliminar el exceso de cobre del cuerpo. Es un aminoácido con un grupo tiol, que le permite formar complejos con iones metálicos, mejorando sus efectos terapéuticos. La sustancia se caracteriza por su naturaleza quiral, existiendo como un solo enantiómero, que es la forma biológicamente activa. (-)-Penicilamina se administra típicamente por vía oral y es conocido por su capacidad para unirse a metales pesados, facilitando su excreción. Tiene una solubilidad relativamente baja en agua y es sensible a la luz y al aire, lo que requiere condiciones de almacenamiento adecuadas. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales y reacciones cutáneas, y su uso requiere monitoreo debido a la posible toxicidad e interacciones con otros medicamentos. En general, (-)-Penicilamina desempeña un papel significativo en el manejo de condiciones médicas específicas a través de sus propiedades químicas únicas.

Fórmula: C₅H₁₁NO₂S

InChI: InChI=1/C5H11NO2S/c1-6(2)4(3-9)5(7)8/h4,9H,3H2,1-2H3,(H,7,8)

Clave InChI: InChIKey=VVNCNSJFMMFHPL-VKHMYHEASA-N

SMILES: [C@@H](C(C)(C)S)(C(O)=O)N

Sinónimos:

• (-)-Penicillamine
• (2S)-2-Azaniumyl-3-methyl-3-sulfanylbutanoate
• (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
• (S)-3,3-Dimethylcysteine
• (S)-Penicillamine
• 2-Amino-3-mercapto-3-methylbutanoic acid
• 3,3-Dimethyl-D-cysteine
• 3-Mercapto-<span class="text-smallcaps">D</span>-valine
• 3-Mercapto-D-valine
• <span class="text-smallcaps">D</span>-(-)-Penicillamine
• <span class="text-smallcaps">D</span>-3-Mercaptovaline
• <span class="text-smallcaps">D</span>-Mercaptovaline
• <span class="text-smallcaps">D</span>-Penamine
• <span class="text-smallcaps">D</span>-Valine, 3-mercapto-
• Artamin
• Cuprenil
• Cuprimine
• Cupripen
• D-3-Mercaptovaline
• D-Mercaptovaline
• D-Penamine
• D-Penicillin
• D-Valine, 3-mercapto-
• D-minus-penicillamine free base
• DPA
• Depamine
• Depen
• Dimethylcysteine
• H-D-Pen-OH
• Kuprenil
• Mercaptyl
• Metalcaptase
• N,N-dimethylcysteine
• Nsc 81549
• Pendramine
• Penicilamina
• Penicillamin
• Penicillamine, D-(-)-
• Penicilllamine
• Perdolat
• Reduced <span class="text-smallcaps">D</span>-penicillamine
• Reduced D-penicillamine
• Reduced penicillamine
• Sufirtan
• Trolovol
• Valine, 3-mercapto-, <span class="text-smallcaps">D</span>-
• Valine, 3-mercapto-, D-
• β-Thiovaline
• D-(-)-Penicillamine
• D-Penicillamine
• 3-mercapto-d-valin
• D(-)-2-AMINO-3-MERCAPTO-3-METHYLBUTANOIC ACID
• DISTAMINE
• (S)-2-AMINO-3-MERCAPTO-3-METHYL-BUTYRIC ACID
• alpha-amino-beta-methyl-beta-mercaptobutyricacid
• D-BETA,BETA-DIMETHYLCYSTEINE
• (S)-Penicillamin
• D[-]-2-AMINO-3-MERCAPTO-3-METHYLBUTANOIC ACID
• 3-Sulfanylvaline
• D-BETA-MERCAPTOVALINE

D-Penicillamine

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: >98.0%(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 149.21

Ref: 3B-P0147

D-(-)-Penicillamine, 98%

CAS: 52-67-5

It is used mainly as chelating agent in heavy metal poisoning as in lead, mercury and copper poisoning. It is used in Wilson's disease. It  is used in pharmacy as chelating agent and as immunosuppressant for treating rheumatoid arthritis by reducing the number of T cells, inhibiting the macrophages,

Fórmula: C₅H₁₁NO₂S

Pureza: 98%

Forma y color: Powder, White to pale cream

Peso molecular: 149.21

Ref: 02-A11446

PENICILLAMINE CRS

CAS: 52-67-5

PENICILLAMINE CRS

Fórmula: C₅H₇NO₃

Forma y color: Powder

Peso molecular: 129.114

Ref: 41-P0310000

Penicillamine

CAS: 52-67-5

Thioglycolic acid and mercaptocarboxylic acids

Fórmula: C₅H₁₁NO₂S

Forma y color: White Off-White Powder

Peso molecular: 149.21 g/mol

Ref: 45-1501006

Penicillamine

CAS: 52-67-5

Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper

Fórmula: C₅H₁₁NO₂S

Pureza: 99.69% - 99.8%

Forma y color: Fine White Or Practically White Crystalline Powder Solid

Peso molecular: 149.21

Ref: TM-T0983

D-Penicillamine

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: 98%

Forma y color: Solid

Peso molecular: 149.2113

Ref: IN-DA0038OE

D-Penicillamine, Ph. Eur. grade

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: ≤ 0.1%

Forma y color: White or almost white crystalline powder

Peso molecular: 149.21

Ref: 7W-GA1554

Penicillamine

CAS: 52-67-5

Penicillamine

Pureza: ≥98%

Peso molecular: 149.21g/mol

Ref: 54-BUP19801

D-Penicillamine

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: 98.0 - 101.0 % (dried basis)

Forma y color: White to off-white powder

Peso molecular: 149.21

Ref: 7W-GA2413

3-Thio-D-valine

CAS: 52-67-5

3-Thio-D-valine

Fórmula: C₅H₁₁NO₂S

Pureza: 98%

Forma y color: white solid

Peso molecular: 149.21g/mol

Ref: 54-OR18365

D-Penicillamine, USP grade

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Pureza: 97.0 - 102.0 %

Forma y color: White to off-white powder or solid

Peso molecular: 149.21

Ref: 7W-GA5612

D-Penicillamine

CAS: 52-67-5

Fórmula: C₅H₁₁NO₂S

Peso molecular: 149.21

Ref: 4Z-P-891

D-Penicillamine-d6

Producto controlado

CAS: 52-67-5

Applications D-Penicillamine-d6 is the isotope labelled analog of D-Penicillamine which is a Penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010), Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010),

Fórmula: C₅D₆H₅NO₂S

Forma y color: Neat

Peso molecular: 155.248

Ref: TR-P223002

D-Penicillamine

CAS: 52-67-5

Applications A Penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010); Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010);

Fórmula: C₅H₁₁NO₂S

Forma y color: Neat

Peso molecular: 149.21

Ref: TR-P223000

D-Penicillamine

CAS: 52-67-5

D-Penicillamine is a nonsteroidal anti-inflammatory drug that is used to treat bowel disease, including ulcerative colitis and Crohn's disease. It has also been used as a treatment for schizophrenia that is unresponsive to other treatments. D-Penicillamine binds covalently to reactive oxygen species (ROS), thereby preventing their interaction with proteins and DNA. The binding of ROS by D-penicillamine can be monitored using electrochemical impedance spectroscopy (EIS). The compound has also been shown to reduce the expression of bcl-2 protein in human cells, which may result in increased oxidative injury and rates of cell proliferation. D-Penicillamine has been shown to have therapeutic benefits for patients with primary sclerosing cholangitis, myocardial infarcts, or preparative high performance liquid chromatography (HPLC) analysis.

Fórmula: C₅H₁₁NO₂S

Pureza: Min 97%

Forma y color: White Powder

Peso molecular: 149.21 g/mol

Ref: 3D-FP26792

H-D-Pen-OH

CAS: 52-67-5

M06142 - H-D-Pen-OH

Fórmula: C₅H₁₁NO₂S

Pureza: 95%

Forma y color: Solid, White to off-white crystalline powder

Peso molecular: 149.21

Ref: 10-M06142

D-Penicillamine-d6 (Racemic)

Producto controlado

CAS: 1795786-79-6, 2714436-24-3, 52-67-5

Fórmula: C₅H₅D₆NO₂S

Forma y color: Neat

Peso molecular: 155.25

Ref: TR-P223006