CAS 520-85-4

Medroxiprogesterona

Descripción:

Medroxiprogesterona es un progestágeno sintético, un tipo de hormona que imita los efectos de la progesterona natural. Se utiliza principalmente en diversas aplicaciones médicas, incluyendo la terapia de reemplazo hormonal, la anticoncepción y el tratamiento de ciertos trastornos menstruales. Medroxiprogesterona se caracteriza por su capacidad para regular la ovulación y la menstruación, lo que lo hace efectivo en el manejo de condiciones como la endometriosis y el sangrado uterino anormal. La sustancia se administra típicamente en formas orales o inyectables, siendo la forma inyectable la que a menudo proporciona efectos prolongados. Químicamente, es un derivado de la 17α-hidroxiprogesterona y presenta una estructura esteroidea modificada que mejora su estabilidad y biodisponibilidad. Medroxiprogesterona actúa uniéndose a los receptores de progesterona, influyendo en la expresión génica y la actividad celular en los tejidos objetivo. Su farmacocinética incluye una vida media relativamente larga, lo que permite una dosificación menos frecuente en entornos clínicos. Al igual que con cualquier medicamento, puede tener efectos secundarios, y su uso debe ser monitoreado por profesionales de la salud para garantizar la seguridad y eficacia.

Fórmula: C₂₂H₃₂O₃

InChI: InChI=1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1

Clave InChI: InChIKey=FRQMUZJSZHZSGN-HBNHAYAOSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]

Sinónimos:

• (6Alpha)-17-Hydroxy-6-Methylpregn-4-Ene-3,20-Dione
• (6Alpha,8Xi,9Xi,14Xi)-6-Methyl-3,20-Dioxopregn-4-En-17-Yl Acetate
• (6α)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione
• 17-Alpha-Hydroxy-6-Alpha-Methylpregn-4-Ene-3,20-Dione
• 17-Hydroxy-6α-methylpregn-4-ene-3,20-dione
• 17-Hydroxy-6α-methylpregn-4-ene-3,20dione
• 17-Hydroxy-6α-methylprogesterone
• 17α-Hydroxy-6α-methylprogesterone
• 6α-Methyl-17-hydroxyprogesterone
• 6α-Methyl-17R-hydroxyprogesterone
• 6α-Methyl-17α-hydroxypregn-4-ene-3,20-dione
• 6α-Methyl-4-pregnen-17-α-ol-3,20-dione
• 6α-Methyl-4-pregnen-17α-ol-3,20-dione
• Hydroxymethylprogesterone
• Medoxyprogesterone
• Medroxiprogesterona
• Medroxy progesterone Base
• Medroxyprogesteron
• Medroxyprogesterone
• Nsc 27408
• Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6α)-
• Pregn-4-ene-3,20-dione, 17-hydroxy-6α-methyl-
• Progesterone, 17-hydroxy-6α-methyl-

Medroxyprogesterone Acetate Related Compound B (17-Hydroxy-6α-methylpregn-4-ene-3,20-dione)

CAS: 520-85-4

Estrogens and progestins

Fórmula: C₂₂H₃₂O₃

Forma y color: White Powder

Peso molecular: 344.23514

Ref: 45-1378023

Medroxyprogesterone

CAS: 520-85-4

Medroxyprogesterone

Pureza: ≥98%

Peso molecular: 344.49g/mol

Ref: 54-BUP14912

Medroxyprogesterone

CAS: 520-85-4

Fórmula: C₂₂H₃₂O₃

Peso molecular: 344.49

Ref: 7W-GP3864

Medroxyprogesterone Acetate EP Impurity B (Medroxyprogesterone Acetate USP Related Compound B, Medroxyprogesterone)

CAS: 520-85-4

Fórmula: C₂₂H₃₂O₃

Forma y color: White To Off-White Solid

Peso molecular: 344.50

Ref: 4Z-M-455

Medroxyprogesterone

CAS: 520-85-4

Medroxyprogesterone

Pureza: 98%

Peso molecular: 344.5g/mol

Ref: 54-OR1024407

4-Pregnen-6a-methyl-17-ol-3,20-dione-2,2,4,6ß,21,21,21-d7

CAS: 520-85-4

Pureza: 98 atom % D

Forma y color: White Solid

Peso molecular: 351.54

Ref: 3U-D7071

MEDROXYPROGESTERONE

CAS: 520-85-4

Pureza: 98%

Peso molecular: 344.494995117188

Ref: 10-F799493

Medroxyprogesterone

Producto controlado

CAS: 520-85-4

Fórmula: C₂₂H₃₂O₃

Forma y color: Neat

Peso molecular: 344.49

Ref: 86-MM0635.00

Medroxyprogesterone

Producto controlado

CAS: 520-85-4

Fórmula: C₂₂H₃₂O₃

Forma y color: Neat

Peso molecular: 344.49

Ref: 04-C14852000

Medroxyprogesterone

CAS: 520-85-4

Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.

Fórmula: C₂₂H₃₂O₃

Pureza: 99.18% - 99.51%

Forma y color: Crystals From Chloroform Solid

Peso molecular: 344.49

Ref: TM-T5040

Medroxy Progesterone

Producto controlado

CAS: 520-85-4

Impurity Medroxyprogesterone Acetate USP Related Compound B
Applications An orally active progestogen used in hormone replacement therepy (HRT), in the past has been used as a component of oral contraceptives.SMedroxyprogesterone Acetate USP Related Compound B.
References Pan, Q., et al.: Mol. Hum. Reprod., 13, 797 (2007), Matsson, P., et al.: J. Pharmacol. Exp. Ther., 323, 19 (2007), Jukosky, J.A., et al.: Bull. Environ. Contam. Toxicol., 81, 230 (2008), Cherkasov, A., et al.: J. Med. Chem., 51, 2047 (2008),

Fórmula: C₂₂H₃₂O₃

Forma y color: Neat

Peso molecular: 344.49

Ref: TR-M203550

Medroxyprogesterone

Producto controlado

CAS: 520-85-4

Medroxyprogesterone is a progestin that has been used in the treatment of endometriosis, premenstrual syndrome, and other medical conditions. It is also used as a contraceptive or to treat abnormal uterine bleeding. Medroxyprogesterone acetate has been shown to inhibit nitrite ion formation in the rat bowel disease model and to have a direct effect on the ovaries. This drug has also been found to increase enzyme activities related to cellular transformation. Medroxyprogesterone acetate is available in combination with nomegestrol acetate (NOMAC) for use as an oral contraceptive medication. The oral bioavailability of medroxyprogesterone acetate is increased by NOMAC, which acts as an inhibitor of first-pass metabolism in the liver.

Fórmula: C₂₂H₃₂O₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 344.49 g/mol

Ref: 3D-FM32162

Medroxyprogesterone

CAS: 520-85-4

Fórmula: C₂₂H₃₂O₃

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 344.50

Ref: 3B-M3113

4-Pregnen-6α-methyl-17-ol-3,20-dione-2,2,4,6,21,21,21-d7

Producto controlado

CAS: 520-85-4

Fórmula: C₂₂D₇H₂₅O₃

Forma y color: Neat

Peso molecular: 351.54

Ref: TR-M203553

Medroxyprogesterone

CAS: 520-85-4

Fórmula: C₂₂H₃₂O₃

Peso molecular: 344.49

Ref: ST-EA-CP-P133015

Medroxyprogesterone Acetate EP Impurity B

CAS: 520-85-4

Fórmula: C₂₂H₃₂O₃

Peso molecular: 344.49

Ref: ST-EA-CP-M96011