CAS 52152-93-9

Cefsulodina sódica

Descripción:

Cefsulodina sódica es un antibiótico semisintético que pertenece a la clase de las cefalosporinas, diseñado específicamente para combatir una variedad de infecciones bacterianas. Es particularmente efectivo contra Pseudomonas aeruginosa y otras bacterias Gram-negativas. El compuesto se caracteriza por su actividad antibacteriana de amplio espectro, que se atribuye a su capacidad para inhibir la síntesis de la pared celular bacteriana. Cefsulodina sódica se administra típicamente por inyección y se utiliza a menudo en entornos clínicos para tratar infecciones en pacientes inmunocomprometidos o aquellos con cepas bacterianas específicas resistentes a otros antibióticos. La sustancia es soluble en agua, lo que facilita su uso en formulaciones intravenosas. Su estructura química incluye un anillo beta-lactámico, una característica de las cefalosporinas, que contribuye a su mecanismo de acción. Al igual que con muchos antibióticos, el uso de Cefsulodina sódica debe guiarse por pruebas de susceptibilidad para minimizar el riesgo de desarrollo de resistencia. Los efectos secundarios potenciales pueden incluir reacciones alérgicas, trastornos gastrointestinales y alteraciones en los recuentos de células sanguíneas, lo que requiere un monitoreo cuidadoso durante el tratamiento.

Fórmula: C₂₂H₁₉N₄O₈S₂·Na

InChI: InChI=1/C22H20N4O8S2.Na/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12;/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34);/q;+1/p-1

Clave InChI: InChIKey=GTZPOHRNWUTXNB-DWBVFMGKSA-N

SMILES: C([O-])(=O)C=1N2[C@@]([C@H](NC([C@H](S(=O)(=O)O)C3=CC=CC=C3)=O)C2=O)(SCC1C[N+]=4C=CC(C(N)=O)=CC4)[H].[Na]

Sinónimos:

• (6R,7R)-3-[(4-carbamoylpyridinium-1-yl)methyl]-8-oxo-7-{[phenyl(sulfo)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 7-(<span class="text-smallcaps">D</span>-α-Sulfophenylacetamido)ceph-3-em-3-(4′-carbamoylpyridinium)methyl-4-carboxylate sodium salt
• <span class="text-smallcaps">D</span>-(-)-SCE-129
• Abbot 46811
• Cefomonil
• Cefsulodin
• Cefsulodin Sodium
• Cefsulodine sodium
• Cgp 7174E
• Monaspor
• Monosodium cefsulodin
• Pseudocef
• Pseudomonil
• Pyocefal
• Pyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, sodium salt (1:1)
• Pyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-phenylsulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, monosodium salt
• Pyridinium, 4-(aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(phenylsulfoacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, hydroxide, inner salt, monosodium salt, [6R-[6α,7β(R*)]]-
• Pyridinium, 4-(aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(phenylsulfoacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, monosodium salt, [6R-[6α,7β(R*)]]-
• Sce 129
• Sodium (6R,7R)-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[[(2R)-2-phenyl-2-sulfonatoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Sodium 3-[(4-Carbamoylpyridinium-1-Yl)Methyl]-8-Oxo-7-{[Phenyl(Sulfonato)Acetyl]Amino}-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
• Sodium cefsulodin
• Sulcephalosporin
• Takesulin
• Tilmapor
• Ulfar
• [6R-(6a,7b)]-4-(Aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(phenylsulfoacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium inner salt monosodium salt
• sodium (6R,7R)-3-[(4-carbamoylpyridinium-1-yl)methyl]-8-oxo-7-{[(2R)-2-phenyl-2-sulfonatoacetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• sodium (6R,7R)-3-[(4-carbamoylpyridinium-1-yl)methyl]-8-oxo-7-{[phenyl(sulfonato)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 7-(D-α-Sulfophenylacetamido)ceph-3-em-3-(4′-carbamoylpyridinium)methyl-4-carboxylate sodium salt
• abbott-46811
• CEFSULODIN SODIUM SALT HYDRATE
• 4-(aminocarbonyl)-1-((2-carboxy-8-oxo-7-((phenylsulfoacetyl)amino)-pyridiniu
• pyridinium,4-(aminocarbonyl)-1-[[(6r,7r)-2-carboxy-8-oxo-7-[[(2r)-phenylsulfoa
• ulfaret
• 5-thio-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-,hydroxide,innersalt,monos
• cetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,innersalt,mono
• CEFSULONDIN SODIUM
• D-(-)-SCE-129
• cgp7174e
• (6r-(6-alpha,7-beta(r*)))-odiumsal
• 4-(AMinocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]aMino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]pyridiniuM
• (6R,7R)-3-[(4-Carbamoylpyridinio)methyl]-8-oxo-7-[(R)-2-phenyl-2-sulfoacetylamino]-5-thia-1-azabicyclo[4.2.0]octan-2-ene-2-carboxylate
• Cefsulodin SodiuM Hydrate
• (6R,7R)-3-[(4-Carbamoylpyridinio)methyl]-8-oxo-7-[(R)-2-phenyl-2-(sodiosulfo)acetylamino]-5-thia-1-azabicyclo[4.2.0]octan-2-ene-2-carboxylate
• hydrogen [6R-[6alpha,7beta(R*)]]-4-carbamoyl-1-[[2-carboxylato-8-oxo-7-(phenylsulphonatoacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium, monosodium salt
• Cefsulodin hydrate sodium salt
• sce129
• CEFSULODIN SODIUM SALT

CEFSULODIN SODIUM SALT, HYDRATE

CAS: 52152-93-9

Fórmula: C₂₂H₁₉N₄NaO₈S₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 554.5280

Ref: IN-DA003OQF

Cefsulodin sodium salt hydrate

CAS: 52152-93-9

Fórmula: C₂₂H₁₉N₄NaO₈S₂·xH₂O

Pureza: ≥ 86.0%

Forma y color: White to light yellow powder

Peso molecular: 554.53 (anhydrous)

Ref: 7W-GA1461

Cefsulodin sodium salt

CAS: 52152-93-9

Cefsulodin sodium salt

Fórmula: C₂₂H₂₀N₄O₈S₂·Na

Pureza: By hplc: 96.5% by area (Typical Value in Batch COA)

Forma y color: off white to faint yellow powder

Peso molecular: 555.54g/mol

Ref: 54-BIC0112

Cefsulodin sodium

CAS: 52152-93-9

Cefsulodin sodium

Pureza: ≥98%

Peso molecular: 554.52g/mol

Ref: 54-BUP15106

Cefsulodin sodium

CAS: 52152-93-9

Cefsulodin sodium (Sulcephalosporin) hydrate is a β lactam antibiotic.

Fórmula: C₂₂H₁₉N₄NaO₈S₂

Pureza: 98.48% - 99.3%

Forma y color: White To Pale Yellow Crystalline Powder

Peso molecular: 554.52

Ref: TM-T0827

Cefsulodin Sodium Salt

Producto controlado

CAS: 52152-93-9

Applications Cefsulodin is a third generation cephalosporin (C258750) antibiotic designed specifically for Pseudomonas Aeruginosa.
References Newall, C.E., et al.: Comprehen. Med. Chem., 2, 609 (1990); Zhao, W.H., et al.: J. Med. MIcrobiol., 57, 974 (2008); Goto, H., et al.: Jap. J. Antibio., 61, 209 (2008);

Fórmula: C₂₂H₁₉N₄O₈S₂·Na

Forma y color: Off White

Peso molecular: 554.53

Ref: TR-C248090

Cefsulodin sodium salt (SCE-129), Antibiotic for Culture Media Use Only

CAS: 52152-93-9

Cefsulodin sodium salt is a beta lactam antibiotic in the third-generation cephalosporin family that inhibits penicillin-binding proteins (PBPs) to disrupt bacterial cell wall synthesis.

Fórmula: C₂₂H₁₉N₄NaO₈S₂

Pureza: Min. 97.0 Area-%

Peso molecular: 554.53 g/mol

Ref: 3D-C-2490

Cefsulodin Sodium Salt Hydrate

CAS: 1426397-23-0, 52152-93-9, 62587-73-9

Fórmula: C₂₂H₁₉N₄NaO₈S₂·xH₂O

Pureza: >95.0%(HPLC)(N)

Forma y color: White to Yellow powder to crystal

Peso molecular: 554.52 (as Anhydrous)

Ref: 3B-C2598

Cefsulodin Sodium Salt (CFS) extrapure, 97%

CAS: 52152-93-9

Fórmula: C₂₂H₁₉N₄NaO₈S₂

Pureza: min. 97%

Forma y color: Off-white to pale yellow, Crystalline powder

Peso molecular: 554.53 (anhy)

Ref: SR-80223

Cefsulodin sodium salt (SCE-129), Antibiotic for Culture Media Use Only

CAS: 52152-93-9

Cefsulodin sodium salt is a beta lactam antibiotic in the third-generation cephalosporin family that inhibits penicillin-binding proteins (PBPs) to disrupt bacterial cell wall synthesis.

Fórmula: C₂₂H₁₉N₄NaO₈S₂

Pureza: Min. 97.0 Area-%

Peso molecular: 554.53 g/mol

Ref: 3D-C-2492