CAS 52214-84-3

Ciprofibrato

Descripción:

Ciprofibrato es un compuesto sintético clasificado como un fibrato, utilizado principalmente en el manejo de la dislipidemia, particularmente para reducir los niveles de triglicéridos y aumentar el colesterol de lipoproteínas de alta densidad (HDL). Su estructura química presenta un grupo fenoxi y un moiety de ácido carboxílico, que contribuyen a sus propiedades moduladoras de lípidos. La sustancia es conocida por su capacidad para activar los receptores activados por proliferadores de peroxisomas (PPARs), que juegan un papel crucial en el metabolismo de lípidos. Ciprofibrato se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal. Exhibe una vida media moderada, lo que permite una dosificación una o dos veces al día. El compuesto generalmente es bien tolerado, aunque los efectos secundarios potenciales pueden incluir trastornos gastrointestinales y problemas relacionados con los músculos. Al igual que otros fibratos, es importante monitorear la función hepática y los niveles de enzimas musculares durante el tratamiento. Ciprofibrato se utiliza a menudo en conjunto con modificaciones en el estilo de vida y otros agentes reductores de lípidos para lograr resultados terapéuticos óptimos en pacientes con niveles elevados de lípidos.

Fórmula: C₁₃H₁₄Cl₂O₃

InChI: InChI=1/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)

Clave InChI: InChIKey=KPSRODZRAIWAKH-UHFFFAOYSA-N

SMILES: ClC1(Cl)C(C1)C2=CC=C(OC(C(O)=O)(C)C)C=C2

Sinónimos:

• 2-(4-(2,2-Dichlorocyclopropyl)phenoxy)2-methylpropanoic acid
• 2-(p-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropionic acid
• 2-[4-(2,2-Dichloro-cyclopropyl)-phenoxy]-2-methyl-propionic acid
• Brn 1984981
• Ccris 173
• Ciprofibrato
• Ciprofibrato [INN-Spanish]
• Ciprofibratum
• Ciprofibratum [INN-Latin]
• Ciprol
• Lipanor
• Modalim
• Propanoic acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-
• Unii-F8252Jgo9S
• Win 35833
• Ciprofibrate
• 2-(p-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropionicacid
• Cipml
• 2-[4-(2，2-Dichlom-cyclopropyl)phenoxy]-2-methy|propanoic acid
• 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-propionicaci
• Ciprofibric acid
• 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-propanoicaci
• 2-[P-(2,2-DICHLOROCYCLOPROPYL)-PHENOXY]-2-METHYLPROPANOIC ACID

Ciprofibrate

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: >98.0%(GC)(T)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 289.15

Ref: 3B-C2667

Ciprofibrate

CAS: 52214-84-3

Forma y color: Neat

Ref: 61-FOR1141.00

Ciprofibrate

CAS: 52214-84-3

Ciprofibrate

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 99.9%

Forma y color: White

Peso molecular: 288.032

Ref: 47-1278

Ciprofibrate impurity standard

CAS: 52214-84-3

Ciprofibrate impurity standard

Forma y color: White

Ref: 47-1312

CIPROFIBRATE CRS

CAS: 52214-84-3

CIPROFIBRATE CRS

Fórmula: C₁₃H₁₄Cl₂O₃

Forma y color: Crystalline Powder. White. Whitish. Powder.

Peso molecular: 289.1545

Ref: 41-Y0000362

Propanoic acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 289.1545

Ref: IN-DA00I9CC

Ciprofibrate

CAS: 52214-84-3

Ciprofibrate

Pureza: ≥98%

Peso molecular: 289.15g/mol

Ref: 54-BUP16708

Ciprofibrate

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Forma y color: Off-White Solid

Peso molecular: 289.15

Ref: 4Z-C-681

2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic Acid

CAS: 52214-84-3

2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic Acid

Pureza: 98%

Peso molecular: 289.15g/mol

Ref: 54-OR1009741

Ciprofibrate

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: ≥ 98.0%

Forma y color: White to light-yellow powder or crystals

Peso molecular: 289.15

Ref: 7W-GP0375

Ciprofibrate

Producto controlado

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Forma y color: Neat

Peso molecular: 289.15

Ref: 86-MM1141.00

Ciprofibrate

CAS: 52214-84-3

Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 99.63% - >99.99%

Forma y color: White Or Almost White Crystalline Powder

Peso molecular: 289.15

Ref: TM-T1264

Ciprofibrate

Producto controlado

CAS: 52214-84-3

Applications Ciprofibrate is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.
References Davison, C., et al.: Drug. Metab. Dispos., 3, 520 (1975), Arnold, A., et al.: J. Pharm. Sci., et al.: 68, 1557 (1979), Tuchman-Duplessis, H., et al.: Toxicology, 12, 1 (1979),

Fórmula: C₁₃H₁₄Cl₂O₃

Forma y color: White

Peso molecular: 289.15

Ref: TR-C482475

2-(4-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 95.0%

Forma y color: Solid, White to slightly pale yellow powder

Peso molecular: 289.15

Ref: 10-F212903

CIPROFIBRATE FOR SYSTEM SUITABILITY A CRS

CAS: 52214-84-3

CIPROFIBRATE FOR SYSTEM SUITABILITY A CRS

Ref: 41-Y0002327

2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid

CAS: 52214-84-3

2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid (CGP) is a drug that blocks the nuclear receptor PPARγ. It has been shown to reduce cholesterol levels by inhibiting the synthesis of cholesterol, as well as reducing liver lesions in vivo. CGP also inhibits the growth of cancer cells through its ability to bind to DNA and regulate transcriptional activity. The response element for this compound is found in the promoter region of the gene encoding the growth factor-β1 (GF-β1), which is an important regulator of cell proliferation, differentiation, and apoptosis. CGP also inhibits peroxisome proliferator activator receptor α (PPARα) and γ (PPARγ). This inhibition leads to decreased expression of genes involved in lipid metabolism, such as acyl CoA synthase and fatty acid synthetase. CGP has also been shown to be carcinogenic in vivo

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 289.15 g/mol

Ref: 3D-FD11320

Ciprofibrate - Bio-X ™

CAS: 52214-84-3

Ciprofibrate is a fibrate drug that is used as a lipid-lowering agent. This drug reduces both LDL and VLDL cholesterol levels in the blood. Ciprofibrate works by reducing the production of triglycerides in the liver and increasing the removal of triglycerides from the blood. This drug is an agonist of peroxisome proliferator-activated receptor alpha.

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 289.15 g/mol

Ref: 3D-BD164311