CAS 52509-14-5

(1,3-Dioxolan-2-ilmetil)trifenilfosfonio bromuro

Descripción:

(1,3-Dioxolan-2-ilmetil)trifenilfosfonio bromuro es una sal de amonio cuaternario caracterizada por su catión triphenylphosphonium y un moiety de dioxolano. Este compuesto típicamente aparece como un sólido blanco a blanco sucio y es soluble en disolventes orgánicos polares, lo que facilita su uso en varias reacciones químicas. La presencia del anillo de dioxolano contribuye a su estabilidad y reactividad, lo que lo convierte en un intermediario útil en la síntesis orgánica, particularmente en la formación de enlaces carbono-carbono. El grupo triphenylphosphonium mejora la lipofilia, permitiendo una mejor permeabilidad de membrana en sistemas biológicos. Además, el anión bromuro actúa como un contraión, que puede influir en la reactividad y solubilidad del compuesto. Esta sustancia se utiliza a menudo en química orgánica sintética, incluyendo aplicaciones en la síntesis de ylidos de fosfonio y otros derivados. Se deben observar precauciones de seguridad al manipular este compuesto, al igual que con muchos compuestos organofosforados, debido a la posible toxicidad y reactividad.

Fórmula: C₂₂H₂₂BrO₂P

InChI: InChI=1/C22H22O2P.BrH/c1-4-10-19(11-5-1)25(18-22-23-16-17-24-22,20-12-6-2-7-13-20)21-14-8-3-9-15-21;/h1-15,22H,16-18H2;1H/q+1;/p-1

Clave InChI: InChIKey=FRHRVQQUICVJDG-UHFFFAOYSA-M

SMILES: [P+](CC1OCCO1)(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]

Sinónimos:

• (1,3-Dioxolane-2-Yl Methyl) Triphenyl Phosphonium Bromide
• 1,3-Dioxylany-2-yl)triphenylphosphonium bromide
• 2-[(1,3)-Dioxolane-2-Yl]-Methyltriphenylphosphonium Bromide
• Labotest-Bb Lt00233112
• Phosphonium, (1,3-Dioxolan-2-Ylmethyl)Triphenyl-, Bromide
• Phosphonium, (1,3-dioxolan-2-ylmethyl)triphenyl-, bromide (1:1)
• Triphenyl-1,3-Dioxolan-2-Ylmethyl-Phosphonium Bromide
• [(1,3-Dioxolan-2-yl)methyl]triphenylphosphanium bromide
• (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide
• (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide, 98 %
• 1,3-Dioxolan-2-ylmethyl-triphenylphosphanium bromide
• (1,3-DIOXOLAN-2-YLMETHYL)TRIPHENYLPHOSPHONIUM BROMIDE 98%

(1,3-Dioxolan-2-yl)methyltriphenylphosphonium Bromide

CAS: 52509-14-5

Fórmula: C₂₂H₂₂BrO₂P

Pureza: >97.0%(T)

Forma y color: White to Light yellow to Light orange powder to crystal

Peso molecular: 429.29

Ref: 3B-D2164

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide, 98%

CAS: 52509-14-5

It finds its applications as a reagent for Wittig olefinations with introduction of a 1,3-dioxolane moiety. It is applied as a reactant for the preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione, for microwave-assisted synthesis of KN-

Fórmula: C₂₂H₂₂BrO₂P

Pureza: 98%

Forma y color: White to cream, Crystals or powder or crystalline powder

Peso molecular: 429.29

Ref: 02-A18882

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

CAS: 52509-14-5

Fórmula: C₂₂H₂₂BrO₂P

Pureza: 97%

Forma y color: Solid

Peso molecular: 429.2866

Ref: IN-DA0032B6

(1,3-Dioxolan-2-ylmethyl)(triphenyl)phosphonium bromide

CAS: 52509-14-5

(1,3-Dioxolan-2-ylmethyl)(triphenyl)phosphonium bromide

Fórmula: C₂₂H₂₂O₂P·Br

Pureza: 98%

Forma y color: off-white solid

Peso molecular: 429.29g/mol

Ref: 54-OR24913

(1,3-Dioxolan-2-yl)methyltriphenylphosphonium Bromide

CAS: 52509-14-5

(1,3-Dioxolan-2-yl)methyltriphenylphosphonium Bromide is a synthetic reagent that is used in the Wittig reaction. It is prepared by reacting p-toluenesulfonic acid with methylene chloride and methoxybenzene. This reagent can be used to synthesize β-unsaturated aldehydes from alkenes and hydroxylamine. The preparation of this reagent involves recrystallizing it from ethanol or ethyl acetate and then hydrogenating it to give (1,3-dioxolan-2-yl)methyl triphenylphosphonium bromide.

Fórmula: C₂₂H₂₂BrO₂P

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 429.29 g/mol

Ref: 3D-FD59861

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

CAS: 52509-14-5

Fórmula: C₂₂H₂₂BrO₂P

Pureza: 97%

Forma y color: Solid, Powder

Peso molecular: 429.294

Ref: 10-F067257

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium Bromide

Producto controlado

CAS: 52509-14-5

Applications (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium Bromide is used as a reactant in the synthesis of ketolides methyloxoerythromycins with antibacterial activity as highly potent against macrolide-resistant and susceptible respiratory pathogens.
References Agouridas, C., et al.: J. Med. Chem., 41, 4080 (1998);

Fórmula: C₂₂H₂₂O₂P·Br

Forma y color: Neat

Peso molecular: 349.38+(79.90)

Ref: TR-D487065