CAS 52619-18-8

Pregna-1,4-dieno-3,20-diona, 9-cloro-11,21-dihidroxi-16-metil-17-[(1-oxopentil)oxi]-, (11β,16β)-

Descripción:

Pregna-1,4-dieno-3,20-diona, 9-cloro-11,21-dihidroxi-16-metil-17-[(1-oxopentil)oxi]-, (11β,16β)-, identificado por el número CAS 52619-18-8, es un compuesto esteroide sintético que exhibe características típicas de los glucocorticoides y progestágenos. Este compuesto presenta una estructura esteroide con múltiples grupos funcionales, incluidos grupos hidroxilo (-OH), un sustituyente cloro y un enlace éter, que contribuyen a su actividad biológica. La presencia de la estructura de 1,4-dieno indica una posible reactividad y estabilidad bajo ciertas condiciones. Su estereoequilibrio específico, denotado por la configuración (11β,16β), es crucial para su interacción con receptores biológicos, influyendo en sus efectos farmacológicos. Este compuesto puede ser investigado por sus posibles aplicaciones terapéuticas, particularmente en los campos de la endocrinología y la salud reproductiva, debido a sus similitudes estructurales con hormonas que ocurren de forma natural. Sin embargo, estudios detallados sobre su farmacodinámica, farmacocinética y perfil de seguridad son esenciales para comprender su potencial completo e implicaciones en el uso médico.

Fórmula: C₂₇H₃₇ClO₆

InChI: InChI=1S/C27H37ClO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1

Clave InChI: InChIKey=CYBACPSHBXABHX-SUYDQAKGSA-N

SMILES: C[C@@]12[C@@](OC(CCCC)=O)(C(CO)=O)[C@@H](C)C[C@]1([C@]3([C@](Cl)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]

Sinónimos:

• (11Beta,16Beta)-9-Chloro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Pentanoate
• 258-050-6
• Pregna-1,4-diene-3,20-dione, 9-chloro-11,21-dihydroxy-16-methyl-17-[(1-oxopentyl)oxy]-, (11β,16β)-

BETAMETHASONE VALERATE IMPURITY MIXTURE CRS

CAS: 2802-10-0, 33755-46-3, 52619-18-8

BETAMETHASONE VALERATE IMPURITY MIXTURE CRS

Ref: 41-Y0001065

(8S,9R,10S,11S,13S,14S,16S,17R)-9-Chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate (Betamethasone Valerate Impurity)

CAS: 52619-18-8

(8S,9R,10S,11S,13S,14S,16S,17R)-9-Chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate (Betamethasone Valerate Impurity)

Pureza: 98%

Ref: 54-OR1039897

Betamethasone Valerate EP Impurity H

CAS: 52619-18-8

Fórmula: C₂₇H₃₇ClO₆

Forma y color: White To Off-White Solid

Peso molecular: 493.04

Ref: 4Z-B-065011

Beclomethasone 17-Valerate

CAS: 52619-18-8

Impurity Betamethasone Valerate EP Impurity H
Applications Beclomethasone 17-Valerate (Betamethasone Valerate EP Impurity H) is a derivative of Beclomethasone (B131000), an glucocorticord used in chronic asthma and allergic rhinitis.
References Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),

Fórmula: C₂₇H₃₇ClO₆

Forma y color: Neat

Peso molecular: 493.03

Ref: TR-B131065

9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-valerate

Producto controlado

CAS: 52619-18-8

Prednisolone is a synthetic corticosteroid that is used in the treatment of a number of lung diseases, including asthma. Prednisolone is used to decrease the inflammation and swelling around the airways and lungs. Prednisolone is used to treat certain skin conditions, such as eczema and dermatitis. This drug also decreases the activity of the immune system by inhibiting production of substances that cause inflammation. The onset of action for prednisolone is typically one day with a duration of up to two weeks. It has been shown to be more effective when taken orally than when applied topically. It may be taken with or without food and can be given as an oral or an intravenous dose. Prednisolone tablets must be dissolved in water before they are placed under the tongue (sublingual). The tablets will dissolve quickly under the tongue, releasing prednisolone into your bloodstream. Enteric-coated tablets should not be crushed or chewed

Fórmula: C₂₇H₃₇ClO₆

Pureza: Min. 95%

Peso molecular: 493.03 g/mol

Ref: 3D-FC156893

Betamethasone Valerate EP Impurity H

CAS: 52619-18-8

Fórmula: C₂₇H₃₇ClO₆

Peso molecular: 493.04

Ref: ST-EA-CP-B5008