CAS 529-35-1

5,6,7,8-Tetrahidro-1-naftol

Descripción:

5,6,7,8-Tetrahidro-1-naftol, con el número CAS 529-35-1, es un compuesto orgánico caracterizado por su estructura bicíclica, que consiste en un sistema de anillos de naftaleno que ha sufrido una hidrogenación parcial. Esto resulta en un compuesto saturado con un grupo hidroxilo (-OH) unido a uno de los átomos de carbono en el marco de naftaleno. El compuesto es típicamente un líquido o sólido incoloro a amarillo pálido, dependiendo de su pureza y temperatura. Es conocido por sus propiedades aromáticas y es soluble en disolventes orgánicos, mientras que es menos soluble en agua debido a su naturaleza hidrofóbica. 5,6,7,8-Tetrahidro-1-naftol se utiliza en diversas aplicaciones, incluyendo como un intermedio en la síntesis orgánica y en la producción de productos farmacéuticos y fragancias. Su reactividad química está influenciada por la presencia del grupo hidroxilo, que puede participar en enlaces de hidrógeno y otras reacciones químicas. Los datos de seguridad indican que debe manejarse con cuidado, ya que puede representar riesgos para la salud si se ingiere o inhala.

Fórmula: C₁₀H₁₂O

InChI: InChI=1S/C10H12O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h3,5,7,11H,1-2,4,6H2

Clave InChI: InChIKey=SCWNNOCLLOHZIG-UHFFFAOYSA-N

SMILES: OC1=C2C(=CC=C1)CCCC2

Sinónimos:

• 1,2,3,4-Tetrahydro-5-hydroxynaphthalene
• 1,2,3,4-Tetrahydro-5-naphthol
• 1,2,3,4-Tetrahydronaphthalen-5-ol
• 1-Hydroxy-5,6,7,8-tetrahydronaphthalene
• 1-Naphthalenol, 5,6,7,8-tetrahydro-
• 1-Naphthol, 5,6,7,8-tetrahydro-
• 5,6,7,8-Tetrahydro-1-hydroxynaphthalene
• 5,6,7,8-Tetrahydro-1-naphthalenol
• 5,6,7,8-Tetrahydro-alpha-naphthol
• 5,6,7,8-Tetrahydro-α-naphthol
• 5,6,7,8-Tetrahydronaphthalen-1-Ol
• 5,6,7,8-Tetrahydronaphthol
• 5-Hydroxytetralin
• Nsc 28822
• Tetrahydro-alpha-naphthol
• Tetrahydro-α-naphthol
• Tetralin-5-ol

5,6,7,8-Tetrahydro-1-naphthol

CAS: 529-35-1

Fórmula: C₁₀H₁₂O

Pureza: >98.0%(GC)

Forma y color: White to Light yellow to Light orange powder to crystal

Peso molecular: 148.21

Ref: 3B-T2816

5,6,7,8-Tetrahydro-1-naphthol, 99%

CAS: 529-35-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₀H₁₂O

Pureza: 99%

Forma y color: White to cream to dark brown to pale cream to gray, Crystals or powder or crystalline powder or fused solid

Peso molecular: 148.21

Ref: 02-L02416

5,6,7,8-Tetrahydro-1-naphthol

CAS: 529-35-1

Fórmula: C₁₀H₁₂O

Pureza: 98%

Forma y color: Solid

Peso molecular: 148.2017

Ref: IN-DA003M96

5,6,7,8-Tetrahydro-1-naphthol

CAS: 529-35-1

Fórmula: C₁₀H₁₂O

Peso molecular: 148.21

Ref: 7W-GL8471

5,6,7,8-Tetrahydronaphthalen-1-ol

CAS: 529-35-1

5,6,7,8-Tetrahydronaphthalen-1-ol

Pureza: 98%

Peso molecular: 148.20g/mol

Ref: 54-OR914367

5,6,7,8-Tetrahydronaphthalen-1-ol

CAS: 529-35-1

Fórmula: C₁₀H₁₂O

Pureza: 95%

Forma y color: Solid

Peso molecular: 148.205

Ref: 10-F242836

5,6,7,8-Tetrahydro-1-naphthol

CAS: 529-35-1

5,6,7,8-Tetrahydro-1-naphthol is a natural compound that belongs to the group of diazonium compounds. It reacts with an alkanoic acid and a hydrochloric acid in the presence of a diazo compound to form an alkylating product. This product can be used as a precursor for the synthesis of other organic compounds. The reaction mechanism has been studied using rat liver microsomes. 5,6,7,8-Tetrahydro-1-naphthol can react with dopamine in human liver samples to form 1-hydroxyindole and phenylhydroxyl radicals (a reactive oxygen species). 5,6,7,8-Tetrahydro-1-naphthol also reacts with soybean lipoxygenase to produce an alkyl radical intermediate that can react with molecular oxygen to form peroxides.

Fórmula: C₁₀H₁₂O

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 148.2 g/mol

Ref: 3D-FT00059

5,6,7,8-Tetrahydro-1-naphthalenol

Producto controlado

CAS: 529-35-1

Applications 5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.
References Pertusati, F., et al.: Eur. J. Med. Chem., 78, 259 (2014); Dong, Y., et al.: Bioorg. Med. Chem. Lett., 19, 6289 (2009);

Fórmula: C₁₀H₁₂O

Forma y color: Neat

Peso molecular: 148.2

Ref: TR-T294265