CAS 530-62-1

1,1'-Carbonyldiimidazol

Descripción:

1,1'-Carbonyldiimidazol (CDI) es un compuesto químico versátil ampliamente utilizado como agente de acoplamiento en la síntesis orgánica, particularmente en la formación de péptidos y ésteres. Presenta una estructura simétrica con dos anillos de imidazol conectados por un grupo carbonilo, lo que contribuye a su reactividad. El CDI es típicamente un sólido blanco a blanco sucio a temperatura ambiente y es soluble en disolventes orgánicos como el diclorometano y el dimetilformamida. Su reactividad proviene del grupo carbonilo, que puede activar nucleófilos, haciéndolo efectivo para reacciones de acilación. Se conoce que el CDI es estable en condiciones ambientales, pero debe manejarse con cuidado debido a su potencial para liberar imidazol al hidrolizarse, lo que puede llevar a reacciones secundarias no deseadas en entornos sensibles. Además, es importante señalar que el CDI puede ser peligroso, y se deben tomar las medidas de seguridad adecuadas al manejar este compuesto, incluyendo el uso de equipo de protección personal y trabajar en un área bien ventilada. En general, el CDI es un reactivo valioso en la química orgánica sintética, facilitando la formación de varios enlaces químicos.

Fórmula: C₇H₆N₄O

InChI: InChI=1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H

Clave InChI: InChIKey=PFKFTWBEEFSNDU-UHFFFAOYSA-N

SMILES: C(=O)(N1C=CN=C1)N2C=CN=C2

Sinónimos:

• 1,1'-Carbonylbis-1H-imidazol
• 1,1'-Carbonylbis-1H-imidazole
• 1,1'-Carbonylbisimidazole
• 1,1'-Carbonyldiimidazole
• 1,1'-carbonilbis-1H-imidazol
• 1-(1H-Imidazol-1-ylcarbonyl)-1H-imidazole
• 1-(1H-Imidazole-1-carbonyl)-1H-imidazole
• Bis(1H-imidazol-1-yl)methanone
• Bis(imidazol-1-yl) ketone
• Bis(imidazol-1-yl)methanone
• Di-1H-imidazol-1-ylmethanone
• Diimidazol-1-yl ketone
• Imidazole, 1,1'-carbonyldi-
• Methanone, di-1H-imidazol-1-yl-
• N,N'-Carbonylbis(imidazole)
• N,N'-Carbonyldiimidazole
• Nsc 67203

1,1'-Carbonyldiimidazole [Coupling Agent for Peptides Synthesis]

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: >97.0%(T)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 162.15

Ref: 3B-C0119

1,1'-Carbonyldiimidazole, 97%

CAS: 530-62-1

Peptide coupling reagent1,1'-Carbonyldiimidazole acts as a coupling reagent and utilized for coupling of amino acids in order to prepare peptide in organic synthesis. It is also used in the preparation of beta-keto sulfones, sulfoxides and beta-enamino acid derivatives. It is used to convert alcohol

Fórmula: C₇H₆N₄O

Pureza: 97%

Forma y color: Crystals or powder or crystalline powder, White to cream

Peso molecular: 162.15

Ref: 02-A14688

1,1‘-Carbonyldiimidazole

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: 98%

Forma y color: Solid

Peso molecular: 162.1487

Ref: IN-DA0032JR

N,N'-Carbonyldiimidazole

CAS: 530-62-1

N,N'-Carbonyldiimidazole is a biological cross-linking agent that has great application in mass spectrometry to detect the purity of compounds.

Fórmula: C₇H₆N₄O

Pureza: 98%

Forma y color: White Solid Crystalline

Peso molecular: 162.15

Ref: TM-T19945

N,N''-Carbonyldiimidazole

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: (Titration) ≥ 97.0%

Forma y color: White, off-white or pale yellow powder or crystals

Peso molecular: 162.15

Ref: 7W-GE9348

1,1'-Carbonyldiimidazole

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Forma y color: White To Off-White Solid

Peso molecular: 162.15

Ref: 4Z-I-078006

1,1'-Carbonyldi(1H-imidazole)

CAS: 530-62-1

1,1'-Carbonyldi(1H-imidazole)

Fórmula: C₇H₆N₄O

Pureza: 98%

Forma y color: white powder

Peso molecular: 162.14874g/mol

Ref: 54-OR18334

1,1'-Carbonyldiimidazole-d6(N,N'-Carbonyldiimidazole)

CAS: 2363787-46-4, 530-62-1

Pureza: 98 atom % D

Peso molecular: 168.2

Ref: 3U-D8187

N,N’-Carbonyldiimidazole

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: 98.0%

Forma y color: Solid

Peso molecular: 162.152

Ref: 10-F003800

Rivaroxaban Impurity 1

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Peso molecular: 162.2

Ref: ST-EA-CP-R17075

N,N'-Carbonyldiimidazole

CAS: 530-62-1

CDI is a coupling agent used mainly for amide and ester formation, but also thioesters, ureas and carbamates. CDI is used in a one-pot procedure, where an acyl imidazolide is formed first upon activation of the carboxylic acid with CDI. The amine or alcohol is then added, and it readily reacts with the active intermediate and the product is generated. CDI does not require the presence of base. The addition to the CDI reaction mixture of carbon dioxide or weakly acid compounds such as imidazole hydrochloride, was reported to increase the reaction rates. CDI can be used in large-scale synthesis thanks to its affordable cost, its availability, and the ease of removal of the by-products during the workup, which are carbon dioxide and imidazole. CDI can be employed as a replacement of the poisonous phosgene, as an imidazolium transfer reagent and in the synthesis of lead sequestering agents.

Fórmula: C₇H₆N₄O

Forma y color: Off-White Powder

Peso molecular: 162.15 g/mol

Ref: 3D-FC02706

1,1'-Carbonyldiimidazole (>90%)

CAS: 530-62-1

Stability Hygroscopic, Moisture Sensitive
Applications Used in the synthesis of peptides. Contains up to 10% imidazole.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pierschbacher, M., et al.: Nature, 309, 30 (1984),

Fórmula: C₇H₆N₄O

Pureza: >90%

Forma y color: White To Off-White

Peso molecular: 162.15

Ref: TR-C177005

N,N-Carbonyldiimidazole (CDI) extrapure AR, 98%

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: min. 98%

Forma y color: Off- white, Crystalline powder, Clear

Peso molecular: 162.15

Ref: SR-67852