CAS 530-62-1

1,1'-Carbonyldiimidazole

Descripción:

1,1'-Carbonyldiimidazole (CDI) est un composé chimique polyvalent largement utilisé comme agent de couplage dans la synthèse organique, en particulier dans la formation de peptides et d'esters. Il présente une structure symétrique avec deux cycles d'imidazole reliés par un groupe carbonyle, ce qui contribue à sa réactivité. Le CDI est généralement un solide blanc à blanc cassé à température ambiante et est soluble dans des solvants organiques tels que le dichlorométhane et le diméthylformamide. Sa réactivité provient du groupe carbonyle, qui peut activer des nucléophiles, le rendant efficace pour les réactions d'acylation. Le CDI est connu pour sa stabilité dans des conditions ambiantes, mais doit être manipulé avec précaution en raison de son potentiel à libérer de l'imidazole lors de l'hydrolyse, ce qui peut entraîner des réactions secondaires indésirables dans des environnements sensibles. De plus, il est important de noter que le CDI peut être dangereux, et des mesures de sécurité appropriées doivent être prises lors de la manipulation de ce composé, y compris l'utilisation d'équipements de protection individuelle et le travail dans un espace bien ventilé. Dans l'ensemble, le CDI est un réactif précieux en chimie organique synthétique, facilitant la formation de divers liaisons chimiques.

Fórmula: C₇H₆N₄O

InChI: InChI=1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H

Clave InChI: InChIKey=PFKFTWBEEFSNDU-UHFFFAOYSA-N

SMILES: C(=O)(N1C=CN=C1)N2C=CN=C2

Sinónimos:

• 1,1'-Carbonylbis-1H-imidazol
• 1,1'-Carbonylbis-1H-imidazole
• 1,1'-Carbonylbisimidazole
• 1,1'-Carbonyldiimidazole
• 1,1'-carbonilbis-1H-imidazol
• 1-(1H-Imidazol-1-ylcarbonyl)-1H-imidazole
• 1-(1H-Imidazole-1-carbonyl)-1H-imidazole
• Bis(1H-imidazol-1-yl)methanone
• Bis(imidazol-1-yl) ketone
• Bis(imidazol-1-yl)methanone
• Di-1H-imidazol-1-ylmethanone
• Diimidazol-1-yl ketone
• Imidazole, 1,1'-carbonyldi-
• Methanone, di-1H-imidazol-1-yl-
• N,N'-Carbonylbis(imidazole)
• N,N'-Carbonyldiimidazole
• Nsc 67203

1,1'-Carbonyldiimidazole [Coupling Agent for Peptides Synthesis]

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: >97.0%(T)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 162.15

Ref: 3B-C0119

1,1'-Carbonyldiimidazole, 97%

CAS: 530-62-1

Peptide coupling reagent1,1'-Carbonyldiimidazole acts as a coupling reagent and utilized for coupling of amino acids in order to prepare peptide in organic synthesis. It is also used in the preparation of beta-keto sulfones, sulfoxides and beta-enamino acid derivatives. It is used to convert alcohol

Fórmula: C₇H₆N₄O

Pureza: 97%

Forma y color: Crystals or powder or crystalline powder, White to cream

Peso molecular: 162.15

Ref: 02-A14688

1,1‘-Carbonyldiimidazole

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: 98%

Forma y color: Solid

Peso molecular: 162.1487

Ref: IN-DA0032JR

N,N'-Carbonyldiimidazole

CAS: 530-62-1

N,N'-Carbonyldiimidazole is a biological cross-linking agent that has great application in mass spectrometry to detect the purity of compounds.

Fórmula: C₇H₆N₄O

Pureza: 98%

Forma y color: White Solid Crystalline

Peso molecular: 162.15

Ref: TM-T19945

N,N''-Carbonyldiimidazole

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: (Titration) ≥ 97.0%

Forma y color: White, off-white or pale yellow powder or crystals

Peso molecular: 162.15

Ref: 7W-GE9348

1,1'-Carbonyldiimidazole

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Forma y color: White To Off-White Solid

Peso molecular: 162.15

Ref: 4Z-I-078006

1,1'-Carbonyldi(1H-imidazole)

CAS: 530-62-1

1,1'-Carbonyldi(1H-imidazole)

Fórmula: C₇H₆N₄O

Pureza: 98%

Forma y color: white powder

Peso molecular: 162.14874g/mol

Ref: 54-OR18334

1,1'-Carbonyldiimidazole-d6(N,N'-Carbonyldiimidazole)

CAS: 2363787-46-4, 530-62-1

Pureza: 98 atom % D

Peso molecular: 168.2

Ref: 3U-D8187

N,N’-Carbonyldiimidazole

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: 98.0%

Forma y color: Solid

Peso molecular: 162.152

Ref: 10-F003800

Rivaroxaban Impurity 1

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Peso molecular: 162.2

Ref: ST-EA-CP-R17075

N,N'-Carbonyldiimidazole

CAS: 530-62-1

CDI is a coupling agent used mainly for amide and ester formation, but also thioesters, ureas and carbamates. CDI is used in a one-pot procedure, where an acyl imidazolide is formed first upon activation of the carboxylic acid with CDI. The amine or alcohol is then added, and it readily reacts with the active intermediate and the product is generated. CDI does not require the presence of base. The addition to the CDI reaction mixture of carbon dioxide or weakly acid compounds such as imidazole hydrochloride, was reported to increase the reaction rates. CDI can be used in large-scale synthesis thanks to its affordable cost, its availability, and the ease of removal of the by-products during the workup, which are carbon dioxide and imidazole. CDI can be employed as a replacement of the poisonous phosgene, as an imidazolium transfer reagent and in the synthesis of lead sequestering agents.

Fórmula: C₇H₆N₄O

Forma y color: Off-White Powder

Peso molecular: 162.15 g/mol

Ref: 3D-FC02706

1,1'-Carbonyldiimidazole (>90%)

CAS: 530-62-1

Stability Hygroscopic, Moisture Sensitive
Applications Used in the synthesis of peptides. Contains up to 10% imidazole.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pierschbacher, M., et al.: Nature, 309, 30 (1984),

Fórmula: C₇H₆N₄O

Pureza: >90%

Forma y color: White To Off-White

Peso molecular: 162.15

Ref: TR-C177005

N,N-Carbonyldiimidazole (CDI) extrapure AR, 98%

CAS: 530-62-1

Fórmula: C₇H₆N₄O

Pureza: min. 98%

Forma y color: Off- white, Crystalline powder, Clear

Peso molecular: 162.15

Ref: SR-67852