CAS 53179-09-2

sulfato de sisomicina

Descripción:

sulfato de sisomicina es un antibiótico aminoglucósido que se utiliza principalmente para tratar infecciones causadas por bacterias Gram-negativas. Se deriva de la fermentación de Micromonospora purpurea y exhibe un amplio espectro de actividad antibacteriana. La sisomicina funciona inhibiendo la síntesis de proteínas bacterianas, dirigiéndose específicamente a la subunidad ribosomal 30S, lo que interrumpe el proceso de traducción y finalmente conduce a la muerte celular. El compuesto se administra típicamente por vía parenteral debido a su mala biodisponibilidad oral. Su solubilidad en agua se mejora en forma de sulfato, lo que lo hace adecuado para uso intravenoso. La sisomicina es conocida por su potencial nefrotóxico y ototóxico, lo que requiere un monitoreo cuidadoso de la función renal y la audición en los pacientes que reciben tratamiento. Además, puede exhibir efectos sinérgicos cuando se usa en combinación con otros antibióticos, mejorando su eficacia contra cepas bacterianas resistentes. Al igual que con otros aminoglucósidos, pueden ser necesarios ajustes de dosis en pacientes con deterioro renal para minimizar el riesgo de efectos adversos.

Fórmula: C₁₉H₃₉N₅O₁₁S

InChI: InChI=1/2C19H37N5O7.5H2O4S/c2*1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;5*1-5(2,3)4/h2*3,9-18,24-27H,4-7,20-23H2,1-2H3;5*(H2,1,2,3,4)/t2*9?,10-,11+,12-,13+,14+,15-,16+,17?,18+,19-;;;;;/m00...../s1

Clave InChI: InChIKey=JVTNJDPXUPRGIE-XMKQNZKISA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3.S(=O)(=O)(O)O

Sinónimos:

• (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside sulfate (2:5)
• 4,6-diamino-3-{[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)pentopyranoside sulfate (2:5) (salt)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</smallcap>-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-<smallcap>D</span>-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-, sulfate (2:5)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</smallcap>-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-<smallcap>D</span>-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-, sulfate (2:5) (salt)
• Antibiotic 66-40 sulfate
• Baymicin
• Extramycin
• Mensiso
• Sisobiotic
• Sisolline
• Sisomicin Sulphate
• Sisomin
• Sisomycin sulfate
• Sissomicin sulfate
• D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-, sulfate (2:5) (salt)
• Sisomicin sulfate
• D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-, sulfate (2:5)
• 6)-o-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-d-glycero-hex-4-enopyranosyl-(1-4))
• Sisomicin sulfate, >=580 μg/mg
• Sisomicin Sulfate (500 mg)
• Sisomicin sulfate, >98%
• antibiotic66-40sulfate
• D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(16)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(14)]-2-deoxy-, sulfate (2:5) (salt) (9CI)
• SISOMYCIN SULPHATE
• O-3-Deoxy-4-C-methyl-3-methylamino-ss-L-arabinopyranosyl-(1->6)-O-[2, 6-diamino-4, 5-dehydro-2,3,4,6-tetradeoxy-a-D-glycero-hexopyranosyl-(1->4)]-2-deoxy-D-streptamine hemiheptasulfate
• Disisomicinpentakis(sulfat)
• SisoMicin Sulfate Salt, USP
• pathomycin
• O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4)]-2-deoxy-D-streptamine sulfate
• O-3-DEOXY-4-C-METHYL-3-METHYLAMINO-BETA-L-ARABINOPYRANOSYL-(1->6)-O-[2, 6-DIAMINO-4,5-DEHYDRO-2,3,4,6-TETRADEOXY-A-D-GLYCERO-HEXOPYRANOSYL-(1->4)]-2-DEOXY-D-STREPTAMINE HEMIHEPTASULFATE
• Sisomicin sulfate, 580 IU/mg
• Sulfuric acid west shuttle m star
• Sisomycin Sulfate USP/EP/BP
• Sisomicin sulfate CRS
• SISOMICIN SULFATE SALT
• disisomicin pentakis(sulphate)

Sisomicin sulfate, 90%

CAS: 53179-09-2

Sisomicin sulfate, 90%

Fórmula: C₁₉H₃₉N₅O₁₁S

Pureza: 90%

Forma y color: White to off-white, Powder

Peso molecular: 545.61

Ref: 02-J66063

SISOMICIN SULFATE CRS

CAS: 53179-09-2

SISOMICIN SULFATE CRS

Fórmula: C₃₈H₈₄N₁₀O₃₄S₅

Forma y color: Powder. White.

Peso molecular: 1385.445

Ref: 41-S0660000

FIRST INTERNATIONAL STANDARD FOR SISOMICIN

CAS: 53179-09-2

FIRST INTERNATIONAL STANDARD FOR SISOMICIN

Fórmula: C₃₈H₈₄N₁₀O₃₄S₅

Peso molecular: 1385.445

Ref: 41-ISA_80_543

Sisomicin Sulfate

CAS: 53179-09-2

Aminoglycoside antibiotics

Fórmula: (C₁₉H₃₇N₅O₇)₂·5H₂SO₄

Forma y color: Light Yellow Powder

Peso molecular: 894.5386

Ref: 45-1612801

Sisomicin Sulfate

CAS: 53179-09-2

Sisomicin sulfate (Pathomycin), a broad-spectrum antibiotic from Micromonospora inyoensis, is strongest against gram-positive bacteria.

Fórmula: C₁₉H₃₇N₅O₇·5H₂SO₄

Pureza: 580IU - 99.83%

Forma y color: Solid

Peso molecular: 1385.43

Ref: TM-T1219

Sisomicin Sulfate Salt

CAS: 53179-09-2

Fórmula: C₃₈H₈₄N₁₀O₃₄S₅

Pureza: 98%

Forma y color: Solid

Peso molecular: 1385.4452

Ref: IN-DA00DEIP

Sisomicin sulfate salt

CAS: 53179-09-2

Fórmula: C₁₉H₃₇N₅O₇·5H₂SO₄

Pureza: ≥ 580μg/mg (C19H37N5O7, dried basis)

Forma y color: White crystalline powder

Peso molecular: 692.72

Ref: 7W-GA7855

Sisomicin Sulfate

Producto controlado

CAS: 53179-09-2

Fórmula: C₁₉H₃₇N₅O₇H₂O₄S

Forma y color: Neat

Peso molecular: 1385.45

Ref: 86-MM3385.00

Sisomycin sulfate

Producto controlado

CAS: 53179-09-2

Fórmula: C₁₉H₃₇N₅O₇H₂O₄S

Forma y color: Neat

Peso molecular: 1385.45

Ref: 04-C16970805

Sisomicin Sulfate

CAS: 53179-09-2

Fórmula: C₁₉H₃₇N₅O₇·5H₂O₄S

Peso molecular: 2 447.54 5 98.08

Ref: 4Z-S-080001

Sisomicin Sulfate Salt

Producto controlado

CAS: 53179-09-2

Applications Sisomicin Sulfate Salt is an aminoglycoside antibiotic displaying a broad spectrum antibiotic activity.
References Cai, Y. et al.: J. Chrom. A., 1085, 124 (2005); Krezel, A. et al.: Bioorg. Med. Chem., 12, 4075 (2004);

Fórmula: C₁₉H₃₇N₅O₇·5H₂O₄S

Forma y color: White

Peso molecular: 1385.45

Ref: TR-S488505

Sisomicin sulfate

CAS: 53179-09-2

Sisomicin sulfate is a sulfate salt form of sisomicin with similar action and applications as sisomicin.

Fórmula: C₁₉H₃₇N₅O₇·5H₂SO₄

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 1,385.45 g/mol

Ref: 3D-AS33969

Sisomicin Sulfate

CAS: 32385-11-8, 53179-09-2

Fórmula: C₁₉H₃₇N₅O₇H₂SO₄

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 692.71

Ref: 3B-I1049