CAS 532-40-1

Monofosfato de tiamina

Descripción:

Monofosfato de tiamina, también conocido como fosfato de tiamina, es un derivado fosforilado de la tiamina (vitamina B1). Se caracteriza por su papel como coenzima en varias reacciones bioquímicas, particularmente en el metabolismo de carbohidratos. La sustancia es típicamente un polvo cristalino blanco a blanco amarillento que es soluble en agua, lo que facilita su actividad biológica. Monofosfato de tiamina es esencial para el correcto funcionamiento de las enzimas involucradas en la descarboxilación de ácidos alfa-ceto y el shunt de monofosfato de hexosa. Su presencia es crucial para la producción de energía y la síntesis de neurotransmisores. En términos de estabilidad, Monofosfato de tiamina es sensible al calor y a condiciones alcalinas, lo que puede llevar a su degradación. Se utiliza comúnmente en suplementos dietéticos y en la fortificación de productos alimenticios para prevenir la deficiencia de tiamina, que puede llevar a condiciones como el beriberi y el síndrome de Wernicke-Korsakoff. En general, Monofosfato de tiamina desempeña un papel vital en el mantenimiento de la salud metabólica y el apoyo a la función neurológica.

Fórmula: C₁₂H₁₈ClN₄O₄PS

InChI: InChI=1/C12H17N4O4PS.ClH/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19);1H

Clave InChI: InChIKey=GUGWNSHJDUEHNJ-UHFFFAOYSA-N

SMILES: C([N+]=1C(C)=C(CCOP(=O)(O)O)SC1)C=2C(N)=NC(C)=NC2.[Cl-]

Sinónimos:

• 2-(3-((6-Imino-2-methyl-1,6-dihydropyrimidin-5-yl)methyl)-4-methylthiazol-3-ium-5-yl)ethyl hydrogen phosphate hydrochloride
• 3-[(4-Amino-2-Methylpyrimidin-5-Yl)Methyl]-4-Methyl-5-[2-(Phosphonooxy)Ethyl]-1,3-Thiazol-3-Ium
• 3-[(4-Amino-2-Methylpyrimidin-5-Yl)Methyl]-4-Methyl-5-[2-(Phosphonooxy)Ethyl]-1,3-Thiazol-3-Ium Chloride
• Extraneurina
• Fosbione
• Monophosphothiamine
• Neurifosforil
• Novaneurina
• Novobeta
• Phosbitamin
• Phosphoric acid, thiamine ester
• Phosphothiamin
• Phosphothiamine
• Sineurina
• Superneurina
• TMP (thiamin ester)
• Thiamin monophosphate
• Thiamine monophosphate
• Thiamine monophosphate chloride
• Thiamine phosphate
• Thiamine phosphoric acid ester chloride
• Thiamine, dihydrogen phosphate (ester)
• Thiamine-P
• Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-, chloride
• Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-, chloride (1:1)
• Vitamin B1 monophosphate chloride
• Vitamin B₁ monophosphate
• Vitamin B₁ phosphate
• LABOTEST-BB LT00847627
• Phosphothiaminum
• Thiamin-p
• Thiamin monophosphate chloride
• 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]thiazolium
• 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(2-phosphonooxyethyl)thiazol-3-ium
• 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-thiazolium chloride
• 3-((4-aMino-2-MethylpyriMidin-5-yl)Methyl)-4-Methyl-5-(2-(phosphonooxy)ethyl)thiazol-3-iuM chloride
• Phosphoric acid 2-[[3-[(2-methyl-4-amino-5-pyrimidinyl)methyl]-4-methylthiazolium]5-yl]ethyl ester
• 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]thiazol-3-ium
• thiaminemonophosphate
• Thiamine-pi

Thiamine Phosphate Chloride

CAS: 532-40-1

Fórmula: C₁₂H₁₈N₄O₄PS·Cl

Forma y color: White To Off-White Solid

Peso molecular: 345.34 35.45

Ref: 4Z-T-8419

Thiamine monophosphate chloride

CAS: 532-40-1

Fórmula: C₁₂H₁₈N₄O₄PS·Cl

Forma y color: White

Peso molecular: 380.79

Ref: 04-C17455600

Vitamin B1 Monophosphate Chloride

CAS: 532-40-1

Applications Vitamin B1 Monophosphate Chloride is a precursor of thiamine pyrophosphate (T344070), a thiamine (T344185) derivative produced by enzyme thiamine pyrophosphatase. Thiamine pyrophosphate is a cofactor used to catalyze various biochemical reactions.
References Stuetz, W., et al.: PLoS One., 7, 36280 (2012); Liu, S.Q., et al.: J. Pharma. Exper. Therap., 341, 775 (2012);

Fórmula: C₁₂H₁₈N₄O₄PS·Cl

Forma y color: White

Peso molecular: 380.79

Ref: TR-V676015

Vitamin B1 monophosphate chloride

CAS: 532-40-1

Vitamin B1 monophosphate chloride is a metabolite of thiamine and is involved in the synthesis of nucleic acids, proteins, and lipids. It also plays an important role in energy metabolism. Vitamin B1 monophosphate chloride has been shown to have a matrix effect on axonal growth, which may be due to its ability to protect against oxidative stress by scavenging reactive oxygen species. It also has been shown to have a toxicological study that showed it was not mutagenic or carcinogenic (neither induced abnormal cell growth nor caused cancer) when administered orally to rats for 2 years at doses up to 1000 mg/kg body weight. The biological properties of Vitamin B1 monophosphate chloride are related to its ability to act as a cofactor for the enzyme pyruvate kinase, which is involved in glycolysis and gluconeogenesis, as well as being part of the pyridoxal phosphate-dependent transferase system that

Fórmula: C₁₂H₁₈ClN₄O₄PS

Pureza: Min. 95%

Peso molecular: 380.79 g/mol

Ref: 3D-AAA53240