CAS 55-03-8

Levotiroxina sódica

Descripción:

Levotiroxina sódica, con el número CAS 55-03-8, es una forma sintética de la hormona tiroidea tiroxina (T4) utilizada principalmente en el tratamiento del hipotiroidismo. Es un polvo cristalino blanco a blanco amarillento que es soluble en agua y tiene una fórmula molecular de C15H11I4NNaO4. La sustancia actúa aumentando la tasa metabólica de los tejidos, influyendo en la síntesis de proteínas y regulando el metabolismo de carbohidratos y grasas. Levotiroxina sódica se administra típicamente por vía oral y se caracteriza por su alta biodisponibilidad y larga vida media, lo que permite una dosificación una vez al día en la mayoría de los casos. Es esencial para mantener un crecimiento y desarrollo normales, particularmente en niños, y juega un papel crítico en el metabolismo energético. La potencia del medicamento puede verse afectada por varios factores, incluyendo la presencia de alimentos, otros medicamentos y características individuales del paciente. Al igual que con cualquier medicamento, el monitoreo de los niveles de hormonas tiroideas es crucial para asegurar la efectividad terapéutica y evitar posibles efectos secundarios asociados con el tratamiento excesivo o insuficiente.

Fórmula: C₁₅H₁₁I₄NO₄·Na

InChI: InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/t12-;/m0./s1

Clave InChI: InChIKey=BRLSOHUOWVCKNI-YDALLXLXSA-N

SMILES: O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(C[C@@H](C(O)=O)N)C=C2I.[Na]

Sinónimos:

• <span class="text-smallcaps">L</span>-Thyroxin Henning
• <span class="text-smallcaps">L</span>-Thyroxine monosodium salt
• <span class="text-smallcaps">L</span>-Thyroxine sodium
• <span class="text-smallcaps">L</span>-Thyroxine sodium salt
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)
• Berlthyrox
• Dathroid
• Droxine
• Eferox
• Elthyrone
• Elthyroxine
• Eltroxin
• Euthyrox
• Eutirox
• L-Thyroxine sodium
• L-Thyroxine sodium salt
• Laevoxin
• Letrox
• Letter
• Levaxin
• Leventa
• Levo-T
• Levolet
• Levoroxine
• Levothroid
• Levothyrox
• Levotirox
• Levotiroxina
• Levoxyl
• Monosodium thyroxine
• NSC 259940
• Novothyrox
• Oroxine
• Puran T 4
• Sodium 2-Amino-3-[4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodophenyl]Propanoate
• Sodium 4-O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosine
• Sodium <span class="text-smallcaps">L</span>-thyroxine
• Sodium levothyroxine
• Sodium thyroxin
• Sodium thyroxinate
• Sodium thyroxine
• Synthroid
• Synthroid sodium
• Synthrox
• T 4Kp
• T4 Montpellier 100
• Thevier
• Throxinique
• Thyradin
• Thyradin S
• Thyrax Duotab
• Thyrex
• Thyro 4
• Thyrosit
• Thyroxevan
• Thyroxine sodium
• Thyroxine sodium salt
• Thyroxine, monosodium salt, <span class="text-smallcaps">L</span>-
• Tiroidine
• Tirosint
• Unithroid
• tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)
• L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
• L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)

L-Thyroxine Sodium Salt Pentahydrate

CAS: 51-48-9, 55-03-8, 6106-07-6

Fórmula: C₁₅H₁₀I₄NNaO₄·5H₂O

Pureza: >98.0%(T)

Forma y color: White to Yellow to Orange powder to crystal

Peso molecular: 888.94

Ref: 3B-T0245

Levothyroxine sodium impurity standard

CAS: 55-03-8

Levothyroxine sodium impurity standard

Forma y color: White To Off-White

Ref: 47-1284

L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodiumsalt

CAS: 55-03-8

Fórmula: C₁₅H₁₀I₄NNaO₄

Pureza: 99%

Forma y color: Solid

Peso molecular: 798.8518

Ref: IN-DA00I9TF

L-Thyroxine sodium

CAS: 55-03-8

L-Thyroxine sodium

Pureza: ≥98%

Peso molecular: 798.85g/mol

Ref: 54-BUP18449

L-Thyroxine sodium

CAS: 55-03-8

L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.

Fórmula: C₁₅H₁₀I₄NO₄·Na

Pureza: 98.74%

Forma y color: Yellowish To Buff-Colored Amorphous Powder Solid

Peso molecular: 798.85

Ref: TM-T22355

Thyroxine Sodium Salt

Producto controlado

CAS: 55-03-8

Stability Hygroscopic
Applications One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),

Fórmula: C₁₅H₁₀I₄NO₄·Na

Forma y color: Neat

Peso molecular: 798.85

Ref: TR-T425601

Levothyroxine sodium

CAS: 55-03-8

Levothyroxine sodium is a thyroid hormone that is used to treat hypothyroidism. It is also used to treat goiter and other thyroid problems. Levothyroxine sodium comes in three different forms: tablets, oral solution, and levothyroxine sodium for injection. The tablet form of levothyroxine sodium is taken by mouth once daily with or without food. Oral solution is taken by mouth twice daily (morning and evening) with or without food. Injection should be given as directed by a physician or healthcare provider. Levothyroxine sodium can interact with many drugs, especially ones that affect the heart or blood sugar levels, such as potassium supplements, diuretics, beta blockers, calcium channel blockers, erythromycin, clarithromycin and ketoconazole. Levothyroxine sodium can also interact with certain foods such as soybean flour and grapefruit juice. Levothyroxine sodium has been shown to have a linear calibration curve in vivo

Fórmula: C₁₅H₁₀I₄NNaO₄

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 798.85 g/mol

Ref: 3D-FL32108