CAS 5536-17-4

Vidarabina

Descripción:

Vidarabina, también conocido como arabinosido de adenina, es un análogo de nucleósido antiviral utilizado principalmente en el tratamiento de infecciones virales, particularmente el virus del herpes simple y el virus varicela-zóster. Se caracteriza por su estructura, que incluye un grupo de azúcar arabinosa unido a una base de adenina, lo que lo distingue de los nucleósidos naturales. Vidarabina exhibe su actividad antiviral al inhibir la síntesis de ADN viral, evitando así la replicación del virus. El compuesto se administra típicamente por vía intravenosa debido a su mala biodisponibilidad oral. Tiene una vida media relativamente corta, lo que requiere un dosificación y monitoreo cuidadosos durante el tratamiento. Vidarabina puede causar efectos secundarios, incluyendo neurotoxicidad y problemas hematológicos, que requieren consideración en entornos clínicos. Su uso ha disminuido con la llegada de agentes antivirales más efectivos, pero sigue siendo un compuesto significativo en el estudio de terapias antivirales. Como entidad química, Vidarabina se clasifica bajo la categoría de nucleósidos de purina y tiene un número CAS específico, 5536-17-4, que se utiliza para su identificación en bases de datos químicas.

Fórmula: C₁₀H₁₃N₅O₄

InChI: InChI=1/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(16)1-19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7+,10-/m1/s1

Clave InChI: InChIKey=OIRDTQYFTABQOQ-UHTZMRCNSA-N

SMILES: O[C@@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CO)[C@H]1O

Sinónimos:

• 6-Amino-9-beta-D-arabinofuranosylpurine
• 6-Amino-9-β-<span class="text-smallcaps">D</span>-arabinofuranosylpurine
• 6-Amino-9-β-D-arabinofuranosylpurine
• 9-(beta-D-Arabinofuranosyl)-9H-purin-6-amine
• 9-(beta-D-glycero-Pentofuranosyl)-9H-purin-6-amine
• 9-Arabinosyladenine
• 9-beta-D-Arabinofuranosyladenine
• 9-β-<span class="text-smallcaps">D</span>-Arabinoadenosine
• 9-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-9H-purin-6-amine
• 9-β-<span class="text-smallcaps">D</span>-Arabinofuranosyladenine
• 9-β-<span class="text-smallcaps">D</span>-Arabinosyladenine
• 9-β-D-Arabinoadenosine
• 9-β-D-Arabinofuranosyl-9H-purin-6-amine
• 9-β-D-Arabinofuranosyl-adenine
• 9-β-D-Arabinofuranosyladenine
• 9-β-D-Arabinosyladenine
• 9-β-D-arabinopyranosyl-9H-purin-6-amine
• 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-
• 9H-Purin-6-amine, 9-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
• 9H-Purin-6-amine, 9-β-D-arabinofuranosyl-
• 9H-purin-6-amine, 9-beta-D-glycero-pentofuranosyl-
• Adenine 9-β-<span class="text-smallcaps">D</span>-arabinofuranoside
• Adenine 9-β-D-arabinofuranoside
• Adenine arabinoside
• Adenine β-<span class="text-smallcaps">D</span>-arabinofuranoside
• Adenine β-D-arabinofuranoside
• Adenine, 9-beta-D-arabinofuranosyl-
• Adenine, 9-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
• Adenine, 9-β-D-arabinofuranosyl-
• Ara-A
• Araadenosine
• Arabinosyladenine
• Arasena-A
• Ci-673
• Nqz-071
• Nsc 247519
• Nsc 404241
• Spongoadenosine
• Vidarabin
• Vidarabina
• Vidarabine anhydrous
• Vira-A
• β-<span class="text-smallcaps">D</span>-Arabinofuranosyladenine
• β-<span class="text-smallcaps">D</span>-Arabinosyladenine
• β-Ara-A
• β-D-Arabinofuranosyladenine
• β-D-Arabinosyladenine
• beta-d-arabinosyladenine
• ADENINE-BETA-D-ARABINOFURANOSIDE
• 9-beta-d-arabinofuranosyl-adenin
• 9-beta-d-arabinofuranosyl-9h-purin-6-amin
• VIDARABINE
• adeninearabinoside
• beta-ara-a
• ci673
• ADENINE-9-BETA-D-ARABINOFURANOSIDE
• ARABINOSYL-ADENINE
• 2'-ARAADENOSINE

Vidarabine

CAS: 5536-17-4

Fórmula: C₁₀H₁₃N₅O₄

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 267.25

Ref: 3B-V0175

Vidarabine Monohydrate

CAS: 24356-66-9, 5536-17-4

Fórmula: C₁₀H₁₃N₅O₄·H₂O

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 285.27

Ref: 3B-V0098

9-β-D-Arabinofuranosyladenine, 99%

CAS: 5536-17-4

Vidarabine is a neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes. Vidarabine is an inhibitor of A cyclase and DNA Polymerase. Used to study the roles of AMP-activated protein kinase (AMPK) in cell signaling. Cell-permeable adenylate cyclase inhibitor;

Fórmula: C₁₀H₁₃N₅O₄

Pureza: 99%

Peso molecular: 267.24

Ref: 02-J65076

Vidarabine

CAS: 5536-17-4

Vidarabine is a nucleoside antibiotic from Streptomyces with antiviral properties, effective against herpes and other DNA viruses.

Fórmula: C₁₀H₁₃N₅O₄

Pureza: 99.85%

Forma y color: White To Off-White Crystalline Powder

Peso molecular: 267.24

Ref: TM-T1506

Adenine 9-β-D-arabinofuranoside

CAS: 5536-17-4

Fórmula: C₁₀H₁₃N₅O₄

Pureza: 95%

Forma y color: Solid

Peso molecular: 267.2413

Ref: IN-DA0034FO

Adenine 9-β-D-arabinofuranoside

CAS: 5536-17-4

Adenine 9-β-D-arabinofuranoside

Pureza: 99%

Peso molecular: 267.24g/mol

Ref: 54-OR1012219

Vidarabine

CAS: 5536-17-4

Vidarabine

Pureza: ≥98%

Peso molecular: 267.24g/mol

Ref: 54-BUP14712

Adenine 9-β-D-arabinofuranoside

CAS: 5536-17-4

Fórmula: C₁₀H₁₃N₅O₄

Pureza: ≥ 99.0%

Forma y color: White to off-white powder

Peso molecular: 267.24

Ref: 7W-GA0167

9-(b-D-Arabinofuranosyl)adenine

CAS: 5536-17-4

9-(b-D-Arabinofuranosyl)adenine is a nucleoside that is used as an antiviral agent. It binds to viral RNA and inhibits viral replication. 9-(b-D-Arabinofuranosyl)adenine has been shown to have potent side-effect profiles, including myocardial infarct, neuronal death, and immunological reactions. These effects are due to its ability to inhibit the synthesis of guanine nucleotides in the heart and brain cells, which are essential for energy production and neurotransmitter release respectively. 9-(b-D-Arabinofuranosyl)adenine also binds to toll-like receptors (TLRs), which are proteins found on the surface of cells that recognize invading microbes or foreign substances. This binding leads to activation of immune response pathways.

Fórmula: C₁₀H₁₃N₅O₄

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 267.24 g/mol

Ref: 3D-NA06007

(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

CAS: 5536-17-4

Fórmula: C₁₀H₁₃N₅O₄

Pureza: 95%

Forma y color: Crystalline Powder,Powder

Peso molecular: 267.245

Ref: 10-F091487

Vidarabine

Producto controlado

CAS: 5536-17-4

Applications Vidarabine, is an antiviral drug which is active against herpes simplex and varicella zoster viruses.
References Sneader, W., et al.: Drug Discovery, 258 (2005); Lee, W. W., et al.: J. Am. Chem. Soc., 82, 2648 (1960);

Fórmula: C₁₀H₁₃N₅O₄

Forma y color: Neat

Peso molecular: 267.24

Ref: TR-V305030