CAS 55466-04-1

Jujubósido A

Descripción:

Jujubósido A es un compuesto natural derivado principalmente del fruto del jujube (Ziziphus jujuba), conocido por sus propiedades medicinales tradicionales. Pertenece a la clase de saponinas y se caracteriza por su estructura glucosídica, que contribuye a su bioactividad. Jujubósido A exhibe varios efectos farmacológicos, incluyendo propiedades ansiolíticas, sedantes y neuroprotectoras, lo que lo hace de interés en la medicina herbal y la farmacología. Se ha estudiado el compuesto por su potencial para modular los sistemas de neurotransmisores, particularmente en relación con el alivio del estrés y la ansiedad. Además, puede poseer efectos antioxidantes y antiinflamatorios, contribuyendo a su potencial terapéutico. Jujubósido A se encuentra típicamente en forma de un polvo blanco a blanco sucio y es soluble en agua y disolventes orgánicos, lo que facilita su extracción y uso en diversas formulaciones. Su perfil de seguridad y eficacia son temas de investigación en curso, particularmente en el contexto de remedios herbales tradicionales y aplicaciones terapéuticas modernas.

Fórmula: C₅₈H₉₄O₂₆

InChI: InChI=1S/C58H94O26/c1-23(2)15-25-16-56(8,72)47-26-9-10-32-54(6)13-12-33(53(4,5)31(54)11-14-55(32,7)57(26)21-58(47,84-25)76-22-57)80-51-46(83-50-43(71)38(66)34(62)24(3)77-50)44(28(61)19-74-51)81-52-45(82-49-41(69)35(63)27(60)18-73-49)40(68)37(65)30(79-52)20-75-48-42(70)39(67)36(64)29(17-59)78-48/h15,24-52,59-72H,9-14,16-22H2,1-8H3/t24-,25-,26+,27+,28-,29+,30+,31-,32+,33-,34-,35-,36+,37+,38+,39-,40-,41+,42+,43+,44-,45+,46+,47-,48+,49-,50-,51-,52-,54-,55+,56-,57-,58-/m0/s1

Clave InChI: InChIKey=KVKRFLVYJLIZFD-OQVAHBRNSA-N

SMILES: C[C@]12[C@@]34[C@@]([C@@]5([C@@](C3)(OC4)O[C@@H](C=C(C)C)C[C@]5(C)O)[H])(CC[C@@]1([C@]6(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]7[C@H](O[C@H]8[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)[C@@H](O[C@H]9[C@H](O[C@H]%10[C@H](O)[C@@H](O)[C@H](O)CO%10)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)O9)[C@@H](O)CO7)CC6)[H])[H])[H]

Sinónimos:

• (3beta,14xi,16beta,23R)-20-hydroxy-16,23:16,30-diepoxydammar-24-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->6)-[beta-D-xylopyranosyl-(1->2)]-beta-D-glucopyranosyl-(1->3)]-L-arabinopyranoside
• (3β,16β,23R)-16,23:16,30-Diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→2)-O-[O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[β-<smallcap>D</smallcap>-xylopyranosyl-(1→2)]-β-<smallcap>D</smallcap>-glucopyranosyl-(1→3)]-α-<smallcap>L</span>-arabinopyranoside
• α-<span class="text-smallcaps">L</smallcap>-Arabinopyranoside, (3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[β-<smallcap>D</smallcap>-xylopyranosyl-(1→2)]-β-<smallcap>D</span>-glucopyranosyl-(1→3)]-
• α-L-Arabinopyranoside, (3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-
• Jujuboside A
• (3β,16β,23R)-16,23:16,30-Diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-α-L-arabinopyranoside

Jujuboside A

CAS: 55466-04-1

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Fórmula: C₅₈H₉₄O₂₆

Forma y color: White Powder

Peso molecular: 1206.60333

Ref: 45-1354717

α-​L-​Arabinopyranoside, (3β,​16β,​23R)​-​16,​23:16,​30-​diepoxy-​20-​hydroxydammar-​24-​en-​3-​yl O-​6-​deoxy-​α-​L-​mannopyranosyl-​(1→2)​-​O-​[O-​β-​D-​glucopyranosyl-​(1→6)​-​O-​[β-​D-​xylopyranosyl-​(1→2)​]​-​β-​D-​glucopyranosyl-​(1→3)​]​-

CAS: 55466-04-1

Fórmula: C₅₈H₉₄O₂₆

Pureza: 98%

Forma y color: Solid

Peso molecular: 1207.3514

Ref: IN-DA00I9WH

Jujuboside A

CAS: 55466-04-1

Fórmula: C₅₈H₉₄O₂₆

Peso molecular: 1207.36

Ref: 7W-GY1525

Jujuboside A

CAS: 55466-04-1

Jujuboside A

Pureza: ≥98%

Peso molecular: 1207.35g/mol

Ref: 54-BUP11056

Jujuboside A

CAS: 55466-04-1

Jujuboside A, a neuroprotective agent, can ameliorates behavioral disorders of the dementia mouse model induced by Aβ1-42. It possesses sedative , anticonvulsant , antianxiety, anti-proliferation, antioxidant, and anti-inflammatory effects, it can notably reduce the damage cause by ISO via promoting the phosphorylation of PI3K, Akt, and mTOR and inhibiting LC3 conversion, which may be a potential choice for the treatment of heart diseases. Jujuboside A can inhibit gamma aminobutyric acid type A receptor, and the hyperactivity of hippocampal CAl area induced by penicillin sodium.

Fórmula: C₅₈H₉₄O₂₆

Pureza: 95%~99%

Peso molecular: 1207.36

Ref: BP-BP0813

Jujuboside A

CAS: 55466-04-1

Jujuboside A: glycoside from Semen Ziziphi Spinosae, may treat Alzheimer's, has neuro-inhibitory effects.

Fórmula: C₅₈H₉₄O₂₆

Pureza: 98% - >99.99%

Forma y color: Solid

Peso molecular: 1207.35

Ref: TM-T3782

Jujuboside a

CAS: 55466-04-1

Natural glycoside

Fórmula: C₅₈H₉₄O₂₆

Pureza: ≥ 95.0 % (HPLC)

Forma y color: Powder

Peso molecular: 1207.37

Ref: 5G-89719

Jujuboside A

CAS: 55466-04-1

Jujuboside A is a saponin compound, which is derived from the seeds of Ziziphus jujuba, commonly known as the jujube or Chinese date. It exhibits a range of biological activities, primarily through its modulation of neurotransmitter systems in the brain. Jujuboside A has been shown to interact with the gamma-aminobutyric acid (GABA)ergic system, enhancing the inhibitory neurotransmission that may lead to its calming and anxiolytic effects.

Fórmula: C₅₈H₉₄O₂₆

Pureza: Min. 95%

Forma y color: Yellow Powder

Peso molecular: 1,207.37 g/mol

Ref: 3D-OJ09904