CAS 55481-88-4

Mollugin

Descripción:

Mollugin es un compuesto que se encuentra de forma natural, derivado principalmente de la especie vegetal *Mollugo nudicaulis*, perteneciente a la familia Molluginaceae. Se caracteriza por su compleja estructura química, que incluye múltiples grupos funcionales que contribuyen a su actividad biológica. Mollugin ha despertado interés en el campo de la química medicinal debido a sus potenciales propiedades farmacológicas, que incluyen actividades antiinflamatorias, antioxidantes y anticancerígenas. El compuesto exhibe una variedad de efectos biológicos, que pueden atribuirse a su capacidad para modular diversas vías celulares. Además, la solubilidad y estabilidad de Mollugin en diferentes disolventes pueden variar, influyendo en su biodisponibilidad y eficacia en aplicaciones terapéuticas. La investigación sobre Mollugin está en curso, con estudios centrados en sus mecanismos de acción, posibles usos terapéuticos y la síntesis de análogos para mejorar sus propiedades. Al igual que con muchos productos naturales, la exploración de las características de Mollugin continúa revelando su importancia tanto en la medicina tradicional como en la farmacología moderna.

Fórmula: C₁₇H₁₆O₄

InChI: InChI=1/C17H16O4/c1-17(2)9-8-12-13(16(19)20-3)14(18)10-6-4-5-7-11(10)15(12)21-17/h4-9,18H,1-3H3

Clave InChI: InChIKey=VLGATXOTCNBWIT-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C2C(=C3C(=C1O)C=CC=C3)OC(C)(C)C=C2

Sinónimos:

• 2H-naphtho[1,2-b]pyran-5-carboxylic acid, 6-hydroxy-2,2-dimethyl-, methyl ester
• Methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
• Rubimaillin
• Smb 00431
• Mollugin
• 2H-Naphtho[1,2-b]pyran-5-carboxylic acid
• Mollugin/rubiMaillin
• 6-Hydroxy-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester
• Mollugin, 98%, from Rubia cordifolia L.
• 6-hydroxy-2, 2-dimethyl-, methylester
• RUBIMAILLIN; MOLLUGIN
• 2-DiMethyl-6-hydroxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid Methyl ester
• 6-Hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylic Acid Methyl Ester
• 2,2-Dimethyl-6-hydroxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester
• MOLLUGIN(SH)

Mollugin

CAS: 55481-88-4

Fórmula: C₁₇H₁₆O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 284.3065

Ref: IN-DA00DE0G

Mollugin

CAS: 55481-88-4

Mollugin

Pureza: ≥95%

Peso molecular: 284.31g/mol

Ref: 54-BUP10672

Mollugin

CAS: 55481-88-4

Fórmula: C₁₇H₁₆O₄

Peso molecular: 284.31

Ref: 7W-GY1430

Methyl 6-Hydroxy-2,2-Dimethyl-2H-Benzo[H]Chromene-5-Carboxylate

CAS: 55481-88-4

Methyl 6-Hydroxy-2,2-Dimethyl-2H-Benzo[H]Chromene-5-Carboxylate

Pureza: 99%

Peso molecular: 284.31g/mol

Ref: 54-OR1013849

Mollugin

CAS: 55481-88-4

Mollugin is a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Mollugin has anticancer efficacy, can modulate the HER2, HO-1, Nrf2 , and NF- κB pathways.

Fórmula: C₁₇H₁₆O₄

Pureza: 95%~99%

Peso molecular: 284.311

Ref: BP-BP1228

Mollugin

CAS: 55481-88-4

Fórmula: C₁₇H₁₆O₄

Pureza: >98.0%(HPLC)

Forma y color: White to Yellow to Orange powder to crystal

Peso molecular: 284.31

Ref: 3B-M3091

Mollugin

CAS: 55481-88-4

Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.

Fórmula: C₁₇H₁₆O₄

Pureza: 99.87% - ≥95%

Forma y color: Solid

Peso molecular: 284.31

Ref: TM-T3673

Mollugin

CAS: 55481-88-4

Oxygen-heterocyclic compound

Fórmula: C₁₇H₁₆O₄

Pureza: ≥ 95.0 % (HPLC)

Peso molecular: 284.31

Ref: 5G-80499

Mollugin

Producto controlado

CAS: 55481-88-4

Applications Mollugin is an anti-tumor agent inducing apoptosis and autophagy in various cancer models.
References Zhang, L. et al.: Biochem. Biophys. Res. Comm., 450, 247 (2014); Idhayadhulla, A. et al.: Bioorg. Chem., 52, 77 (2014);

Fórmula: C₁₇H₁₆O₄

Forma y color: Neat

Peso molecular: 284.31

Ref: TR-M487600

Mollugin

CAS: 55481-88-4

Mollugin is a bioactive compound, which is derived from the plant Rubia cordifolia. As a phytochemical, it is part of the anthraquinone family, isolated through extraction processes from the root of its source plant. Its mode of action involves modulating various biochemical pathways, notably exhibiting anti-inflammatory, anticancer, and antioxidant activities. These effects are primarily mediated through the inhibition of specific enzymes and signaling pathways, including the NF-κB and MAPK pathways, which are central to inflammatory and cancer processes.

Pureza: Min. 95%

Ref: 3D-FM145252