CAS 55750-63-5

N-(6-Maleimidocaproyloxi)succinimida

Descripción:

N-(6-Maleimidocaproyloxi)succinimida, con el número CAS 55750-63-5, es un compuesto químico comúnmente utilizado en aplicaciones de bioconjugación y etiquetado de proteínas. Presenta un grupo funcional maleimida, conocido por su capacidad para reaccionar selectivamente con grupos tiol en proteínas y péptidos, facilitando la formación de enlaces tioéter estables. Este compuesto se caracteriza por su moiety de succinimida, que mejora su solubilidad y reactividad en entornos acuosos. Típicamente, aparece como un sólido blanco a blanco sucio y es soluble en disolventes orgánicos como el dimetilsulfóxido (DMSO) y el dimetilformamida (DMF). La presencia del grupo maleimida permite la conjugación específica en el sitio, lo que lo hace valioso en el desarrollo de sistemas de entrega de fármacos dirigidos, biosensores y herramientas de diagnóstico. Además, su estabilidad en condiciones fisiológicas lo hace adecuado para diversas aplicaciones bioquímicas. Las condiciones adecuadas de manejo y almacenamiento son esenciales para mantener su reactividad y prevenir la degradación.

Fórmula: C₁₄H₁₆N₂O₆

InChI: InChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2

Clave InChI: InChIKey=VLARLSIGSPVYHX-UHFFFAOYSA-N

SMILES: O(C(CCCCCN1C(=O)C=CC1=O)=O)N2C(=O)CCC2=O

Sinónimos:

• 1-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
• 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
• 1H-Pyrrole-2,5-dione, 1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-
• 2,5-Dioxopyrrolidin-1-yl 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate
• 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
• 6-Maleimidohexanoic acid N-succinimidyl ester
• N-(6-Maleimide caproyloxy) succinimide
• N-(6-Maleimideocaproyloxy)succinimide
• N-(6-Maleimidocaproyloxy)succinimide
• N-(epsilon-Maleimidocaproyloxy)succinimide
• N-(ε-Maleimidocaproyloxy)succinimide
• N-Succinimidyl 6-maleimidohexanoate

6-Maleimidocaproic acid N-succinimidyl ester, 95%

CAS: 55750-63-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₄H₁₆N₂O₆

Pureza: 95%

Peso molecular: 308.29

Ref: 02-H65996

N-Succinimidyl 6-maleimidohexanoate

CAS: 55750-63-5

Fórmula: C₁₄H₁₆N₂O₆

Pureza: 98%

Forma y color: Solid

Peso molecular: 308.2866

Ref: IN-DA003TCH

EMCS

CAS: 55750-63-5

EMCS

Pureza: ≥98%

Peso molecular: 308.29g/mol

Ref: 54-BUP15806

N-(E-Maleimidocaproyloxy)succinimide

CAS: 55750-63-5

N-(E-Maleimidocaproyloxy)succinimide

Fórmula: C₁₄H₁₆N₂O₆

Pureza: By hplc: 99.2% (Typical Value in Batch COA)

Forma y color: white to off-white solid

Peso molecular: 308.29g/mol

Ref: 54-BICL222

N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]

CAS: 55750-63-5

Fórmula: C₁₄H₁₆N₂O₆

Pureza: >98.0%(N)

Forma y color: White to Light yellow powder to crystaline

Peso molecular: 308.29

Ref: 3B-S0428

N-(6-Maleimidocaproyloxy)succinimide

CAS: 55750-63-5

Fórmula: C₁₄H₁₆N₂O₆

Peso molecular: 308.29

Ref: 4Z-A-4619

EMCS

CAS: 55750-63-5

EMCS is a heterobifunctional crosslinker for hapten, enzyme conjugates, and ADC protective groups.

Fórmula: C₁₄H₁₆N₂O₆

Pureza: 99.37% - 99.88%

Forma y color: White To Cream Colored Crystals

Peso molecular: 308.29

Ref: TM-T14061

N-Succinimidyl 6-maleimidohexanoate

CAS: 55750-63-5

Fórmula: C₁₄H₁₆N₂O₆

Pureza: 98%

Forma y color: Solid, Crystalline Powder

Peso molecular: 308.29

Ref: 10-F079601

N-(ε-Maleimidocaproyloxy) Succinimide extrapure, 98%

CAS: 55750-63-5

Fórmula: C₁₄H₁₆N₂O₆

Peso molecular: 308.29

Ref: SR-50062

N-Succinimidyl 6-Maleimidohexanoate

Producto controlado

CAS: 55750-63-5

Applications N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE (cas# 55750-63-5) is a useful research chemical.

Fórmula: C₁₄H₁₆N₂O₆

Forma y color: Neat

Peso molecular: 308.28

Ref: TR-S688065

N-Succinimidyl 6-Maleimidohexanoate

CAS: 55750-63-5

Fórmula: C₁₄H₁₆N₂O₆

Peso molecular: 308.29

Ref: ST-EA-CP-A18014

6-Maleimidocaproic acid N-hydroxysuccinimide ester

CAS: 55750-63-5

6-Maleimidocaproic acid N-hydroxysuccinimide ester (6MCA-NHS) is a fluorescent probe that reacts with the hydroxyl group of fatty acids in human serum and other biological samples. 6MCA-NHS binds to the carboxylic acid group at the end of a fatty acid molecule, forming a covalent bond. This process generates light emission that can be detected by a fluorescence probe to measure changes in pH or other chemical properties within the solution. 6MCA-NHS has been used as a tumor treatment, where laser ablation is used to break up tumor cells and release 6MCA-NHS into the cytoplasm. The drug can then bind to DNA molecules and inhibit protein synthesis, which results in cell death.

Fórmula: C₁₄H₁₆N₂O₆

Pureza: Min. 95%

Forma y color: White Off-White Powder

Peso molecular: 308.29 g/mol

Ref: 3D-FM48296