CAS 5579-84-0

Diclorhidrato de betahistina

Descripción:

Diclorhidrato de betahistina es un análogo de la histamina que se utiliza principalmente en el tratamiento de la enfermedad de Ménière y otros trastornos vestibulares. Actúa como un agonista selectivo de los receptores H1 de histamina y un antagonista de los receptores H3, lo que ayuda a mejorar el flujo sanguíneo en el oído interno y a reducir síntomas como el vértigo y el tinnitus. La sustancia se administra típicamente en forma oral y es conocida por su relativamente buena biodisponibilidad. Químicamente, se caracteriza por su forma de sal dihidrocloruro, que mejora su solubilidad en agua. Diclorhidrato de betahistina generalmente es bien tolerado, con efectos secundarios comunes que incluyen trastornos gastrointestinales y dolores de cabeza. Su mecanismo de acción implica la modulación de la liberación de neurotransmisores y la mejora de la microcirculación en el oído interno, contribuyendo a sus efectos terapéuticos. El compuesto se clasifica en la categoría de antihistamínicos, aunque no presenta las propiedades sedantes comúnmente asociadas con muchos otros medicamentos en esta clase. En general, Diclorhidrato de betahistina es un medicamento valioso para el manejo de trastornos del equilibrio relacionados con la disfunción del oído interno.

Fórmula: C₈H₁₄Cl₂N₂

InChI: InChI=1/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H

Clave InChI: InChIKey=XVDFMHARQUBJRE-UHFFFAOYSA-N

SMILES: C(CNC)C1=CC=CC=N1.Cl

Sinónimos:

• 2-Pyridineethanamine, N-methyl-, dihydrochloride
• 2-Pyridineethanamine, N-methyl-, hydrochloride (1:2)
• Betahistine dihydrochloride
• Betahistine hydrochloride
• Betaserc
• N-methyl-2-(pyridin-2-yl)ethanamine dihydrochloride
• Pyridine, 2-[2-(methylamino)ethyl]-, dihydrochloride
• Sinmenier
• Vasomotal
• PT 9
• 2-(2-(METHYLAMINO)ETHYL)PYRIDINE DIHYDROCHLORIDE 99%
• n-methyl-2-pyridineethanamindihydrochloride
• 2-(BETA-METHYLAMINOETHYL)PYRIDINE DIHYDROCHLORIDE
• METHYL[2-(2-PYRIDYL)ETHYL]AMINE DIHYDROCHLORIDE
• Betahistine Hydrochloride CP2000
• BetahistineHCl
• BETAHISTINE DIHYDROCHLORIDE:METHYL(2-[2-PYRIDYL]ETHYL)AMINE
• 2-(2-(METHYLAMINO)ETHYL)PYRIDINE DIHYDROCHLORIDE
• BETAHISTINE DIHYDROCHLORIDE (2-(2-(METHYLAMINO)ETHYL)PYRIDINE DIHYDROCHLORIDE)
• Betahistine 2 hcl
• Serc
• BETA-HISTINE DIHDROCHLORIDE
• N-Methyl-2-pyridin-2-ylethanamine dihydrochloride
• Microser

Betahistine dihydrochloride

CAS: 5579-84-0

Betahistine dihydrochloride

Fórmula: C₈H₁₂N₂HCl

Pureza: 99.5%

Forma y color: White. To. Off-White

Peso molecular: 172.07673

Ref: 47-824

BETAHISTINE DIHYDROCHLORIDE CRS

CAS: 5579-84-0

BETAHISTINE DIHYDROCHLORIDE CRS

Fórmula: C₈H₁₄Cl₂N₂

Forma y color: White. Whitish. Powder.

Peso molecular: 209.1162

Ref: 41-Y0000391

Betahistine Hydrochloride

CAS: 5579-84-0

Compounds containing an unfused pyridine ring in the structure, nesoi

Fórmula: C₈H₁₂N₂·2HCI

Forma y color: White Light Yellow Crystalline Powder

Peso molecular: 415.92464

Ref: 45-1065618

2-Pyridineethanamine, N-methyl-, dihydrochloride

CAS: 5579-84-0

Fórmula: C₈H₁₄Cl₂N₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 209.1162

Ref: IN-DA00I9YC

Betahistine-13C-d3 DiHCl

CAS: 5579-84-0, 5638-76-6

Fórmula: C₇₁₃CH₉D₃N₂·2HCl

Forma y color: Pale Orange Solid

Peso molecular: 140.21 2*36.46

Ref: 4Z-B-364

Betahistine Dihydrochloride

CAS: 5579-84-0

Betahistine Dihydrochloride

Pureza: 98%

Peso molecular: 209.12g/mol

Ref: 54-OR1012385

Betahistine dihydrochloride

CAS: 5579-84-0

Betahistine dihydrochloride

Pureza: ≥98%

Peso molecular: 209.12g/mol

Ref: 54-BUP18938

Betahistine DiHCl

CAS: 5579-84-0

Fórmula: C₈H₁₂N₂·2HCl

Forma y color: Pale Orange Solid

Peso molecular: 136.20 2*36.46

Ref: 4Z-B-368

Betahistine Dihydrochloride

CAS: 5579-84-0

Forma y color: Neat

Ref: 86-MM0587.00

Betahistine dihydrochloride

CAS: 5579-84-0

Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator.

Fórmula: C₈H₁₄Cl₂N₂

Pureza: 99.22% - 99.88%

Forma y color: White To Light Yellow Crystalline Powder

Peso molecular: 209.12

Ref: TM-T0246

Betahistine Dihydrochloride

CAS: 5579-84-0

Fórmula: C₈H₁₂N₂(HCl)

Peso molecular: 136.2 : 2(36.46)

Ref: ST-EA-CP-B11007

Betahistine Dihydrochloride

CAS: 5579-84-0

Applications Betahistine is most commonly used to treat the symptoms of Ménière's disease and vertigo. Vasodilator.
References Gilligan, P., et al.: J. Med. Chem., 43, 1641 (2000), Keller, P., et al.: Bioorg. Med. Chem., 8, 1213 (2000), Hauger, R., et al.: Pharmacol. Rev., 55, 21 (2003), Han, X., et al.: Bioorg. Med. Chem. Lett., 15, 3870 (2005),

Fórmula: C₈H₁₂N₂·2ClH

Forma y color: Neat

Peso molecular: 209.12

Ref: TR-B324001

Betahistine dihydrochloride

CAS: 5579-84-0

Betahistine dihydrochloride is a medication used to treat Ménière's disease, vertigo, and dizziness. It is an antihistamine that acts on histamine H1 receptors in the vestibular system. Betahistine also has vasodilatory effects, which are mediated by its ability to activate the α-adrenergic receptors in the vascular endothelium. This drug is approved for use as a treatment for Ménière's disease and vertigo, but is not approved for treating dizziness. Betahistine dihydrochloride can be administered either intravascularly or orally. The drug undergoes a phase transition from liquid to solid at low temperatures, so it should be stored at room temperature in sealed ampoules and vials to prevent crystallization. Treatment trials have shown that low-dose betahistine (less than 40 mg) may be as effective as higher doses of betahistine (40-120 mg) in the

Fórmula: C₈H₁₂N₂·2HCl

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 209.12 g/mol

Ref: 3D-FB138972

N-methyl-N-(2-pyridin-2-ylethyl)amine dihydrochloride

CAS: 5579-84-0

Fórmula: C₈H₁₄Cl₂N₂

Pureza: 95+%

Forma y color: Solid

Peso molecular: 209.11

Ref: 10-F351346