
CAS 55824-11-8
:Cannabigerivarin
CAS:Producto controladoCannabingerovarin is a phytocannabinoid that acts as an agonist at TRPV3 (EC50= 2.4 uM)1,2. It is reported to efficiently desensitise the TRPV3 ion channel, proving it to be a potential target to develop TRPV3 desensitisers2. TRPV3 activity has been implicated in a variety of diseases, including bone and metabolic disease and cancer3. In vitro studies on human kidney cells expressing a murine recombinant receptor showed intracellular Ca2+ elevation and ion channel desensitization. In vivo studies on mice gastrointestinal tract models have shown their exploitation in both physiological and pathological conditions.1,2 It is also reported to act as a l-α-lysophosphatidylinositol signaling inhibitor, which may affect pain and tumorigenesis through binding to downstream ligand GRP553.
Fórmula:C19H28O2Pureza:Min. 95%Peso molecular:288.42 g/molCannabigerovarin
CAS:Cannabigerovarin (CBGV) is a compound categorized as a phytocannabinoid.Fórmula:C19H28O2Peso molecular:288.42

