CAS 55869-99-3

Anisodamina

Descripción:

Anisodamina, con el número CAS 55869-99-3, es un compuesto químico que pertenece a la clase de los alcaloides tropánicos. Se deriva principalmente de la planta Anisodus tanguticus y exhibe propiedades anticolinérgicas, lo que significa que puede inhibir la acción de la acetilcolina en los receptores muscarínicos. Esta característica hace que Anisodamina sea útil en diversas aplicaciones médicas, particularmente en el tratamiento de condiciones como la bradicardia y ciertos tipos de shock. El compuesto es conocido por su capacidad para inducir vasodilatación y mejorar la circulación sanguínea, lo que puede ser beneficioso en el manejo de problemas cardiovasculares. Anisodamina también tiene efectos neuroprotectores potenciales y puede ser explorado por su papel en el tratamiento de trastornos neurológicos. Su estructura química presenta un anillo tropánico, que es típico de muchos alcaloides, contribuyendo a su actividad biológica. Al igual que con muchos agentes farmacológicos, el perfil de seguridad, la dosis y los posibles efectos secundarios de Anisodamina deben ser considerados cuidadosamente en entornos clínicos.

Fórmula: C₁₇H₂₃NO₄

InChI: InChI=1S/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3/t12-,13-,14+,15+,16-/m0/s1

Clave InChI: InChIKey=WTQYWNWRJNXDEG-RBZJEDDUSA-N

SMILES: CN1[C@]2([C@@H](O)C[C@@]1(C[C@H](OC([C@H](CO)C3=CC=CC=C3)=O)C2)[H])[H]

Sinónimos:

• (-)-(3S,6S,2′S)-6β-Hydroxyhyoscyamine
• (-)-6β-Hydroxyhyoscyamine
• 6-Hydroxyhyoscyamine
• Anisodamine
• Benzeneacetic acid, α-(hydroxymethyl)-, (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [1R-[1α,3β(S*),5α,6α]]-
• Bicyclo[3.2.1]Oct-3-Yl 3-Hydroxy-2-Phenylpropanoate
• Bicyclo[3.2.1]oct-3-yl tropate
• Hyoscyamine, 6-hydroxy-
• (αS)-α-(Hydroxymethyl)benzeneacetic acid (1R,5R)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3α-yl ester
• 6-hydroxy-hyoscyamin
• Hyoscyamine, 6-hydroxy-(6ci, 7ci)
• aceanisodaMine
• alpha-(hydroxymethyl)-benzeneaceticaci6-hydroxy-8-methyl-8-azabicyclo(3.2
• (1r-(1-alpha,3-beta(s*),5-alpha,6-alpha))-.1)oct-3-yleste
• alpha-(Hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
• (αS)-α-(Hydroxymethyl)benzeneacetic acid (1R,5R)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]octa-3α-yl ester
• Benzeneacetic acid, alpha-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (1R-(1-alpha,3-beta(S*),5-alpha,6-alpha))-
• (αS)-α-Hydroxymethylbenzeneacetic acid (1β,5β)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-3α-yl ester
• Atropine iMpurity E (7-hydroxyhyoscyaMine)
• Benzeneacetic acid, alpha-(hydroxymethyl)-, (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (alphas)-
• [S,(-)]-α-(Hydroxymethyl)benzeneacetic acid (1R,5R)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-3α-yl ester

[(1S,3S,5S,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate

CAS: 55869-99-3

Fórmula: C₁₇H₂₃NO₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 305.3688

Ref: IN-DA01DNA6

Atropine EP Impurity D and E (Mixture of 6-β-Hydroxyhyoscyamine and 7-β-Hydroxyhyoscyamine)

CAS: 126371-43-5, 55869-99-3

Fórmula: C₁₇H₂₃NO₄

Forma y color: White To Off-White Solid

Peso molecular: 305.37

Ref: 4Z-A-151007

Anisodamine

CAS: 55869-99-3

Anisodamine

Pureza: ≥98%

Peso molecular: 305.37g/mol

Ref: 54-BUP12119

6-Hydroxyhyoscyamine (Mixture of Diastereomers)

CAS: 126371-43-5, 55869-99-3

Stability Hygroscopic
Applications Mixture of 6R-Hydroxyhyoscyamine (H942815) and 6S-Hydroxyhyoscyamine (H942820). A derivative of Hyoscyamine (H674300).

Fórmula: C₁₇H₂₃NO₄

Forma y color: Neat

Peso molecular: 305.37

Ref: TR-H942900

6-Hydroxyhyoscyamine

CAS: 55869-99-3

6-Hydroxyhyoscyamine is a natural molecule that can bind to DNA. It has been shown to have high affinity for the 5'-GCAT-3' sequence and high specificity for the G-quadruplex structure. 6-Hydoxyhyoscyamine also has a phase transition temperature of 146°C, which may be due to the hydrogen bonds it forms with water molecules. It has been shown that 6-hydroxyhyoscyamine inhibits tumor cell growth by binding to a specific region of the promoter region of the gene encoding for growth factor β1 (GFβ1) and preventing transcription. This agent also has an inhibitory effect on tumor angiogenesis and vascular permeability, which may be related to its ability to inhibit nitric oxide production in endothelial cells. The compound is also known as anisodamine and can be used as an injection solution for patients who have had a myocardial infarct.

Fórmula: C₁₇H₂₃NO₄

Pureza: Min. 97 Area-%

Forma y color: Powder

Peso molecular: 305.37 g/mol

Ref: 3D-FH44857

Anisodamine

CAS: 55869-99-3

Anisodamine is similar to scopolamine & atropine, blocks muscarinic/nicotinic receptors, aids shock-related microcirculation & organophosphate studies.

Fórmula: C₁₇H₂₃NO₄

Pureza: 98% - 98.16%

Forma y color: Solid

Peso molecular: 305.37

Ref: TM-T21532

Atropine EP Impurity D

CAS: 55869-99-3

Fórmula: C₁₇H₂₃NO₄

Peso molecular: 305.37

Ref: ST-EA-CP-A206004